Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Amber W, Wang"'
Autor:
Alessandra Castiglioni, Yagai Yang, Katherine Williams, Alvin Gogineni, Ryan S. Lane, Amber W. Wang, Justin A. Shyer, Zhe Zhang, Stephanie Mittman, Alan Gutierrez, Jillian L. Astarita, Minh Thai, Jeffrey Hung, Yeqing Angela Yang, Tony Pourmohamad, Patricia Himmels, Marco De Simone, Justin Elstrott, Aude-Hélène Capietto, Rafael Cubas, Zora Modrusan, Wendy Sandoval, James Ziai, Stephen E. Gould, Wenxian Fu, Yulei Wang, James T. Koerber, Shomyseh Sanjabi, Ira Mellman, Shannon J. Turley, Sören Müller
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023)
Abstract TGFβ signaling is associated with non-response to immune checkpoint blockade in patients with advanced cancers, particularly in the immune-excluded phenotype. While previous work demonstrates that converting tumors from excluded to inflamed
Externí odkaz:
https://doaj.org/article/fa5b40b8c1aa4ad3abed292446b9c3af
Autor:
Amber W. Wang, Yue J. Wang, Adam M. Zahm, Ashleigh R. Morgan, Kirk J. Wangensteen, Klaus H. Kaestner
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 9, Iss 1, Pp 121-143 (2020)
Background & Aims: The adult liver is the main detoxification organ and routinely is exposed to environmental insults but retains the ability to restore its mass and function upon tissue damage. However, extensive injury can lead to liver failure, an
Externí odkaz:
https://doaj.org/article/14e9131189f24fd4b460426315103daa
Autor:
Akshay T. Krishnamurty, Justin A. Shyer, Minh Thai, Vineela Gandham, Matthew B. Buechler, Yeqing Angela Yang, Rachana N. Pradhan, Amber W. Wang, Patricia L. Sanchez, Yan Qu, Beatrice Breart, Cécile Chalouni, Debra Dunlap, James Ziai, Justin Elstrott, Neelie Zacharias, Weiguang Mao, Rebecca K. Rowntree, Jack Sadowsky, Gail D. Lewis, Thomas H. Pillow, Barzin Y. Nabet, Romain Banchereau, Lucinda Tam, Roger Caothien, Natasha Bacarro, Merone Roose-Girma, Zora Modrusan, Sanjeev Mariathasan, Sören Müller, Shannon J. Turley
Publikováno v:
Nature. 611:148-154
Recent single-cell studies of cancer in both mice and humans have identified the emergence of a myofibroblast population specifically marked by the highly restricted leucine-rich-repeat-containing protein 15 (LRRC15)1–3. However, the molecular sign
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1180240064ddca96a7dbfb51299c508a
https://doi.org/10.1038/s41586-022-05272-1
https://doi.org/10.1038/s41586-022-05272-1
Autor:
Yeqing Angela Yang, Christian Cox, Matthew B. Buechler, Zora Modrusan, Merone Roose-Girma, Rachana N. Pradhan, Roger Caothien, Richard Bourgon, Sören Müller, Amber W. Wang, Akshay T. Krishnamurty, Shannon J. Turley, Aslihan Karabacak Calviello, Joseph R. Arron, Lucinda Tam
Publikováno v:
Nature. 593:575-579
Fibroblasts are non-haematopoietic structural cells that define the architecture of organs, support the homeostasis of tissue-resident cells and have key roles in fibrosis, cancer, autoimmunity and wound healing1. Recent studies have described fibrob
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43cd94afe9f708264d32b72292b58008
https://doi.org/10.1038/s41586-021-03549-5
https://doi.org/10.1038/s41586-021-03549-5
Autor:
Alessandra Castiglioni, Markus Brown, Jillian L. Astarita, Mark Z. Chen, Lucinda Tam, Richard Bourgon, Claudia X. Dominguez, Shilpa Keerthivasan, Cecile Chalouni, Wendy Sandoval, Viviana Cremasco, Xiumin Wu, Yeqing Angela Yang, Andrey S. Shaw, Frederic J. de Sauvage, Ira Mellman, Elaine E. Storm, Catherine B Carbone, Merone Roose-Girma, Zora Modrusan, Amber W. Wang, Akshay T. Krishnamurty, Yasin Senbabaoglu, Wyne P. Lee, Jonas Doerr, Maximilian Nitschké, Shannon J. Turley, Varun N. Kapoor, Ryan Lane, Sören Müller, Christine Moussion
Publikováno v:
Nature Immunology. 22:571-585
Fibroblastic reticular cells (FRCs) are specialized stromal cells that define tissue architecture and regulate lymphocyte compartmentalization, homeostasis, and innate and adaptive immunity in secondary lymphoid organs (SLOs). In the present study, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2383e3a737dd8c2478d0ddc2038bf224
https://doi.org/10.1038/s41590-021-00920-6
https://doi.org/10.1038/s41590-021-00920-6
Autor:
Amber W. Wang
Publikováno v:
Biometrics. 78:415-416
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2360be157c8eb22a15e7f94ab086eb1a
https://doi.org/10.1111/biom.13572
https://doi.org/10.1111/biom.13572
Autor:
Akshay T, Krishnamurty, Justin A, Shyer, Minh, Thai, Vineela, Gandham, Matthew B, Buechler, Yeqing Angela, Yang, Rachana N, Pradhan, Amber W, Wang, Patricia L, Sanchez, Yan, Qu, Beatrice, Breart, Cécile, Chalouni, Debra, Dunlap, James, Ziai, Justin, Elstrott, Neelie, Zacharias, Weiguang, Mao, Rebecca K, Rowntree, Jack, Sadowsky, Gail D, Lewis, Thomas H, Pillow, Barzin Y, Nabet, Romain, Banchereau, Lucinda, Tam, Roger, Caothien, Natasha, Bacarro, Merone, Roose-Girma, Zora, Modrusan, Sanjeev, Mariathasan, Sören, Müller, Shannon J, Turley
Publikováno v:
Nature. 611(7934)
Recent single-cell studies of cancer in both mice and humans have identified the emergence of a myofibroblast population specifically marked by the highly restricted leucine-rich-repeat-containing protein 15 (LRRC15)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::59eeda4a38c0af3f0f6cad81ea9ce623
https://pubmed.ncbi.nlm.nih.gov/36171287
https://pubmed.ncbi.nlm.nih.gov/36171287
Autor:
Kivanc Kose, Pratik Chandrani, Allan C. Halpern, Teguru Tembo, Anthony Santella, Madison Li, William Phillips, Cristian Navarrete-Dechent, Christi Alessi Fox, Melissa Pulitzer, Nicholas Kurtansky, Paras Mehta, Milind Rajadhyaksha, Chih-Shan Jason Chen, Kimeil King, Ning Yang, Salvador González, Liang Deng, Shuaitong Li, Aditi Sahu, Anabel Alfonso, Stephen W. Dusza, Haaris Jilani, Piyush Kumar, Melissa Gill, Gary Peterson, Anthony M. Rossi, Ashfaq A. Marghoob, Miguel Cordova, Amber W. Wang, Shen Yin
Immunotherapies have shown unprecedented clinical benefits in several malignancies1–3. However, clinical responses remain variable and unpredictable, indicating the need to develop predictive platforms that can improve patient stratification4. Phen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::278f899a4aded4e422eb46aa3b2c5d8b
https://doi.org/10.1101/2021.06.10.447835
https://doi.org/10.1101/2021.06.10.447835
Autor:
Melissa Pulitzer, Nicholas Kurtansky, Ning Yang, Kivanc Kose, Milind Rajadhyaksha, Shuaitong Liu, Chih-Shan Jason Chen, Kimeil King, Liang Deng, Aditi Sahu, Ashfaq A. Marghoob, Anthony M. Rossi, Madison Li, Melissa Gill, Pratik Chandrani, Christi Alessi Fox, Haaris Jilani, Amber W. Wang, William Phillips, Anabel Alfonso, Anthony Santella, Paras Mehta, Allan C. Halpern, Teguru Tembo, Stephen W. Dusza, Salvador González, Miguel Cordova
Publikováno v:
Biophotonics Congress 2021.
In vivo phenotyping of tumor-immune microenvironment (TiME) for predicting response to immunotherapy in patients using non-invasive reflectance confocal microscopy (RCM) demonstrates high molecular and treatment response correlation.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::38383f3c5464cb0df204472ac3e72210
https://doi.org/10.1364/boda.2021.dth2a.5
https://doi.org/10.1364/boda.2021.dth2a.5
Autor:
Amber W. Wang, Yemin Lan, Ashleigh Morgan, Eric L. Waite, Yitzhak Reizel, Klaus H. Kaestner, Long Gao, Elisabetta Manduchi, Andrew D. Wells
The FoxA transcription factors are critical for liver development through their pioneering activity, which initiates a highly complex regulatory network thought to become progressively resistant to the loss of any individual hepatic transcription fac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f02570c984faf0c25fdb7187ce9901c0