Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Amber Vu"'
Autor:
Elizabeth B Draganova, Hui Wang, Melanie Wu, Shiqing Liao, Amber Vu, Gonzalo L Gonzalez-Del Pino, Z Hong Zhou, Richard J Roller, Ekaterina E Heldwein
Publikováno v:
PLoS Pathogens, Vol 20, Iss 1, p e1011936 (2024)
Nuclear egress is an essential process in herpesvirus replication whereby nascent capsids translocate from the nucleus to the cytoplasm. This initial step of nuclear egress-budding at the inner nuclear membrane-is coordinated by the nuclear egress co
Externí odkaz:
https://doaj.org/article/4ec664c6fbd343e48c9bf997df69f327
Autor:
Amber Vu, Paul B. McCray
Publikováno v:
Hum Gene Ther
The lung has long been a target for gene therapy, yet efficient delivery and phenotypic disease correction has remained challenging. Although there have been significant advancements in gene therapies of other organs, including the development of sev
Publikováno v:
J Virol
Nuclear envelope budding in herpesvirus nuclear egress may be negatively regulated, since the pUL31/pUL34 nuclear egress complex heterodimer can induce membrane budding without capsids when expressed ectopically or on artificial membranes in vitro, b
Autor:
Amber Vu, Douglas E. Smith, Alexis Catala, Jean Sippy, Mariam Ordyan, Carlos Enrique Catalano, Choon-Seok Oh, Michael Feiss, David Ortiz, Joshua Pajak, Gaurav Arya, Damian delToro
Publikováno v:
J Mol Biol
Many viruses employ ATP-powered motors for genome packaging. We combined genetic, biochemical, and single-molecule techniques to confirm the predicted Walker-B ATP-binding motif in the phage λ motor and to investigate the roles of the conserved resi
Autor:
David Ortiz, Damian delToro, Jean Sippy, Choon-Seok Oh, Michael Feiss, Gaurav Arya, Joshua Pajak, Amber Vu, Alexis Catala, Mariam Ordyan, Carlos Enrique Catalano, Douglas E. Smith
Publikováno v:
Nucleic Acids Research
ASCE ATPases include ring-translocases such as cellular helicases and viral DNA packaging motors (terminases). These motors have conserved Walker A and B motifs that bind Mg2+-ATP and a catalytic carboxylate that activates water for hydrolysis. Here
Publikováno v:
Journal of virology. 90(23)
Nuclear egress of herpesviruses is accompanied by changes in the architecture of the nuclear membrane and nuclear lamina that are thought to facilitate capsid access to the inner nuclear membrane (INM) and curvature of patches of the INM around the c