Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Amber Tariq"'
Publikováno v:
Journal Riphah College of Rehabilitation Sciences, Vol 10, Iss 01 (2022)
Background: Pressure ulcers are the most common condition in bedridden patients. Almost every country is dealing with this condition instead primarily or secondary. Proper positioning and care are needed and preferred in this situation by physiothera
Externí odkaz:
https://doaj.org/article/91b54dde4f0547a692fc745544856962
Autor:
Amber Tariq, JiaBei Lin, Meredith E. Jackrel, Christina D. Hesketh, Peter J. Carman, Korrie L. Mack, Rachel Weitzman, Craig Gambogi, Oscar A. Hernandez Murillo, Elizabeth A. Sweeny, Esin Gurpinar, Adam L. Yokom, Stephanie N. Gates, Keolamau Yee, Saurabh Sudesh, Jacob Stillman, Alexandra N. Rizo, Daniel R. Southworth, James Shorter
Publikováno v:
Cell Reports, Vol 28, Iss 8, Pp 2080-2095.e6 (2019)
Summary: Hsp104 is an AAA+ protein disaggregase, which can be potentiated via diverse mutations in its autoregulatory middle domain (MD) to mitigate toxic misfolding of TDP-43, FUS, and α-synuclein implicated in fatal neurodegenerative disorders. Pr
Externí odkaz:
https://doaj.org/article/bf589229a4c8478bb067db7496f89daf
Publikováno v:
The FASEB Journal. 36
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::57216d148c7d9bd27c77535a70ff5ff8
https://doi.org/10.1096/fasebj.2022.36.s1.r3428
https://doi.org/10.1096/fasebj.2022.36.s1.r3428
Autor:
Edward Chuang, Ryan R. Cupo, Meredith E. Jackrel, Amber Tariq, Korrie L. Mack, Kim A. Caldwell, Laura M. Castellano, Jamie E. DeNizio, Hanna Kim, James Shorter, JiaBei Lin, Xiaohui Yan, Guy A. Caldwell
SummaryHsp104 is an AAA+ protein disaggregase that solubilizes and reactivates proteins trapped in aggregated states. We have engineered potentiated Hsp104 variants to mitigate toxic misfolding of α-synuclein, TDP-43, and FUS implicated in fatal neu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2841ba1d281e017ba4cd2fea677a6bf
Autor:
Matthew A. Sochor, Michelle S. Go, James Shorter, Amber Tariq, Leland Mayne, Esin Gurpinar, S. Walter Englander, Elizabeth A. Sweeny, Zhong-yuan Kan
Publikováno v:
J Biol Chem
Hsp104 is a hexameric AAA(+) ring translocase, which drives protein disaggregation in nonmetazoan eukaryotes. Cryo-EM structures of Hsp104 have suggested potential mechanisms of substrate translocation, but precisely how Hsp104 hexamers disaggregate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61c428561ea54fa6940cf78eae8f3e10
https://pubmed.ncbi.nlm.nih.gov/31882541
https://pubmed.ncbi.nlm.nih.gov/31882541
Publikováno v:
Journal of visualized experiments : JoVE. (93)
Many protein-misfolding disorders can be modeled in the budding yeast Saccharomyces cerevisiae. Proteins such as TDP-43 and FUS, implicated in amyotrophic lateral sclerosis, and α-synuclein, implicated in Parkinson’s disease, are toxic and form cy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61070bf475a7dc3b03d3bfbec54838ff
https://pubmed.ncbi.nlm.nih.gov/25407485
https://pubmed.ncbi.nlm.nih.gov/25407485
Publikováno v:
Asian Social Science. 10
Stress is a universal and inevitable component of life. The article reports findings of a study aimed to determine the sources of stress among medical practitioners in private hospitals. The context of the study is medical practitioners in private ho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4de4dbd06d21327b56b648fd1df35ea0
https://doi.org/10.5539/ass.v10n22p111
https://doi.org/10.5539/ass.v10n22p111
Publikováno v:
Mediterranean Journal of Social Sciences, Vol 3, Iss 1 (2012)
Trust has been recognized as a multi-dimensional concept with its various components. However, the missing link of trust and collaboration is still being observed in human resource management literature. This study deliberates upon exploring the link
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doajarticles::ac9a28755a6d763077aa691137659097
http://www.richtmann.org/journal/index.php/mjss/article/view/10989
http://www.richtmann.org/journal/index.php/mjss/article/view/10989
Publikováno v:
Mediterranean Journal of Social Sciences, Vol 3, Iss 1 (2012)
Organizations focus upon increased revenue generated by its employees, competitive workforce and employee dedication for achieving its strategic goals in order to meet the challenges of 21st century. However, in this era of hyper competition work lif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doajarticles::967608e7344040c9315f9b49d1565064
http://www.richtmann.org/journal/index.php/mjss/article/view/10991
http://www.richtmann.org/journal/index.php/mjss/article/view/10991
Publikováno v:
FASEB Journal; May2022 Supplement, Vol. 36, pN.PAG-N.PAG, 1p