Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Amber T. Kaplan"'
Autor:
Ching Wen Tseng, Dianhua Jiang, Amber T. Kaplan, George Y. Liu, Pierre Kyme, Ramachandran Murali, Antoine Soliman, Moshe Arditi, Jiurong Liang, Stacey L. Kolar, David M. Underhill, Victor Nizet
Publikováno v:
Cell Host & Microbe. 18:694-704
In response to tissue injury, hyaluronan (HA) polymers are cleaved by host hyaluronidases, generating small fragments that ligate Toll-like receptors (TLRs) to elicit inflammatory responses. Pathogenic bacteria such as group B Streptococcus (GBS) exp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef6ac0f32a5176133c0f2e8c92d97b78
https://doi.org/10.1016/j.chom.2015.11.001
https://doi.org/10.1016/j.chom.2015.11.001
Autor:
Yuxin B. Ouyang, Yi Ouyang, Nancy Q. Liu, Amber T. Kaplan, Ozlem Equils, Charles F. Simmons, Martin Hewison, Venu Lagishetty
Publikováno v:
The Journal of Immunology. 186:5968-5974
The vitamin D-activating enzyme 1α-hydroxylase (CYP27B1) and vitamin D receptor (VDR) support anti-inflammatory responses to vitamin D in many tissues. Given the high basal expression of CYP27B1 and VDR in trophoblastic cells from the placenta, we h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4469a42a89c9da17de9cbf8663dc71c7
https://doi.org/10.4049/jimmunol.1003332
https://doi.org/10.4049/jimmunol.1003332
Publikováno v:
Journal of Parasitology. 95:477-480
In aquatic ecosystems, dense populations of snails can shed millions of digenean trematode cercariae every day. These short-lived, free-living larvae are rich in energy and present a potential resource for consumers. We investigated whether estuarine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddb13a952e5bfb3f35a6a5a54001768f
https://doi.org/10.1645/ge-1737.1
https://doi.org/10.1645/ge-1737.1
Autor:
Feng Qian, Tian Wang, Ruth R. Montgomery, Fengwei Bai, Richard A. Flavell, Amber T. Kaplan, Erol Fikrig, John F. Anderson, Terrence Town
Publikováno v:
Immunity. 30(2):242-253
West Nile virus (WNV), a mosquito-transmitted single-stranded RNA (ssRNA) flavivirus, causes human disease of variable severity. We investigated Toll-like receptor 7-deficient (Tlr7(-/-)) and myeloid differentiation factor 88-deficient (Myd88(-/-)) m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63f03d7f016d9eaf94c5b6ea80f92760
Autor:
Pierre Kyme, Jun Ma, Ching Wen Tseng, Andrea J. Wolf, Amber T. Kaplan, David M. Underhill, Courtney A. Becker, George Y. Liu
The importance of type I IFNs in the host response to viral infection is well established; however, their role in bacterial infection is not fully understood. Several bacteria (both Gram-positive and -negative) have been shown to induce IFN-β produc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb8e282895b06c3c04358ccac8a31909
https://europepmc.org/articles/PMC3478442/
https://europepmc.org/articles/PMC3478442/
Autor:
Andrea Arruda, Moshe Arditi, David M. Underhill, Takahiro Shimada, George Y. Liu, Amber T. Kaplan, Kenichi Shimada, Andrea J. Wolf, Christopher N. Reyes
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 187(11)
Signaling by innate immune receptors initiates and orchestrates the overall immune responses to infection. Macrophage receptors recognizing pathogens can be broadly grouped into surface receptors and receptors restricted to intracellular compartments
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::997bf945f5719e504c69030db3ba5299
https://pubmed.ncbi.nlm.nih.gov/22031762
https://pubmed.ncbi.nlm.nih.gov/22031762
Autor:
Amber T. Kaplan, J. Low, Nancy Q. Liu, Ozlem Equils, Lisa Nguyen, Martin Hewison, George Y. Liu
The active form of vitamin D, 1,25-dihydroxyvitamin D (1,25(OH)(2)D), is a potent inducer of the antimicrobial protein cathelicidin, CAMP (LL37). In macrophages this response is dependent on intracrine synthesis of 1,25(OH)(2)D from precursor 25-hydr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ca30c0db49457205b71b3bef458ad65
https://europepmc.org/articles/PMC2704027/
https://europepmc.org/articles/PMC2704027/
Autor:
Cristina Bertolotto, George Y. Liu, Kelly S. Doran, Ozlem Equils, Andy Uh, Kathy Chung, Calvin J. Hobel, Hande Kocak, Amber T. Kaplan, Charles F. Simmons
Publikováno v:
Microbial pathogenesis. 45(3)
Group B streptococcus (GBS) is one of the leading causes of neonatal infection; however the molecular mechanisms involved are not clearly known. Here we used high and low hemolytic GBS isolates and mutant GBS that lacks beta-hemolysin expression and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::479fb118d0941edc795913d53f3a4078
https://pubmed.ncbi.nlm.nih.gov/18599257
https://pubmed.ncbi.nlm.nih.gov/18599257