Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Amber S. Zhou"'
Autor:
Amber S. Zhou, John B. Tucker, Christina M. Scribano, Andrew R. Lynch, Caleb L. Carlsen, Sophia T. Pop-Vicas, Srishrika M. Pattaswamy, Mark E. Burkard, Beth A. Weaver
Publikováno v:
PLoS Biology, Vol 21, Iss 10 (2023)
Externí odkaz:
https://doaj.org/article/77177300a1494d9cb91032c08bf0716d
Autor:
Khoa A. Tran, Stefan J. Pietrzak, Nur Zafirah Zaidan, Alireza Fotuhi Siahpirani, Sunnie Grace McCalla, Amber S. Zhou, Gopal Iyer, Sushmita Roy, Rupa Sridharan
Publikováno v:
Cell Reports, Vol 27, Iss 6, Pp 1726-1741.e5 (2019)
Summary: Elucidating the mechanism of reprogramming is confounded by heterogeneity due to the low efficiency and differential kinetics of obtaining induced pluripotent stem cells (iPSCs) from somatic cells. Therefore, we increased the efficiency with
Externí odkaz:
https://doaj.org/article/8e6a7b35caec4373ae0421253ff37534
Publikováno v:
eLife, Vol 11 (2022)
Chromosomal instability (CIN)—persistent chromosome gain or loss through abnormal mitotic segregation—is a hallmark of cancer that drives aneuploidy. Intrinsic chromosome mis-segregation rate, a measure of CIN, can inform prognosis and is a promi
Externí odkaz:
https://doaj.org/article/7f548a7a7f9c4dcaa81c622dfb9ba2ff
Autor:
Amber Lasek, Jun Wan, Kayla Correia-Staudt, Tim S. Bugni, Kari B. Wisinski, Amber S. Zhou, Stephanie M. McGregor, Amy M. Fowler, Mark E. Burkard, Jonathan Fitzgerald, John B. Tucker, Karla Esbona, Lauren M. Zasadil, Christina M. Scribano, Amye J. Tevaarwerk, Ryan Molini, Beth A. Weaver, Ruth O'Regan, Angela M. Lager, Jennifer Laffin, Rick Chappell
Publikováno v:
Sci Transl Med
Paclitaxel (Taxol) is a cornerstone of cancer treatment. However, its mechanism of cytotoxicity is incompletely understood and not all patients benefit from treatment. We show that patients with breast cancer did not accumulate sufficient intratumora
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c001273086d6d430d83a6c11b9ba2676
https://doi.org/10.1126/scitranslmed.abd4811
https://doi.org/10.1126/scitranslmed.abd4811
Autor:
Jeffrey D. Lifson, Christoph H. Fellinger, Michael Farzan, Hema R. Kondur, Kimberly L. Weisgrau, Nancy Schultz-Darken, Guangping Gao, Barnett Alfant, Amber S. Zhou, Wendy Newton, Neha R. Prasad, Meredith E. Davis-Gardner, Matthew R. Gardner, Lisa M. Kattenhorn, Eva G. Rakasz, Jesse A. Weber
A number of simian and simian human immunodeficiency viruses (SIV and SHIV, respectively) have been used to assess the efficacy of HIV-1 vaccine strategies. Among these, SIVmac239 is considered among the most stringent because, unlike SHIV models, it
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad3b092778486d063519fc4db3c02712
https://europepmc.org/articles/PMC6716512/
https://europepmc.org/articles/PMC6716512/
Autor:
Michael Farzan, Barnett Alfant, Christoph H. Fellinger, Amber S. Zhou, Matthew R. Gardner, Jesse A. Weber
Publikováno v:
Journal of virology. 93(14)
The engineered antibody-like entry inhibitor eCD4-Ig neutralizes every human immunodeficiency virus type 1 (HIV-1), HIV-2, and simian immunodeficiency virus isolate it has been tested against. The exceptional breadth of eCD4-Ig derives from its abili
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8879bbfb7fb38d7082d00bfb7a41abcd
https://pubmed.ncbi.nlm.nih.gov/31068428
https://pubmed.ncbi.nlm.nih.gov/31068428
Autor:
Ina Fetzer, Michael Farzan, Jesse A. Weber, Neha R. Prasad, Matthew R. Gardner, Meredith E. Davis-Gardner, Barnett Alfant, Amber S. Zhou
Broadly neutralizing antibodies (bNAbs) target five major epitopes on the HIV-1 envelope glycoprotein (Env). The most potent bNAbs have median half-maximal inhibitory concentration (IC(50)) values in the nanomolar range, and the broadest bNAbs neutra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::feadcd4a4f3a78c51fb92920d7447729
https://europepmc.org/articles/PMC6384058/
https://europepmc.org/articles/PMC6384058/
Autor:
Brian D. Quinlan, Michael Farzan, Vinita R. Joshi, Matthew R. Gardner, Christoph H. Fellinger, Neha R. Prasad, Amber S. Zhou, Hema R. Kondur
Publikováno v:
Journal of Virology. 90:7822-7832
The HIV-1 envelope glycoprotein (Env) is a trimer of gp120/gp41 heterodimers that mediates viral entry. Env binds cellular CD4, an association which stabilizes a conformation favorable to its subsequent association with a coreceptor, typically CCR5 o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ff953623c641d15c509b4b729146465
https://doi.org/10.1128/jvi.00803-16
https://doi.org/10.1128/jvi.00803-16
Autor:
Sushmita Roy, Sunnie Grace McCalla, Rupa Sridharan, Gopal Iyer, Khoa A Tran, Amber S. Zhou, Nur Zafirah Zaidan, Stefan J. Pietrzak, Alireza Fotuhi Siahpirani
Publikováno v:
Cell reports
Cell Reports, Vol 27, Iss 6, Pp 1726-1741.e5 (2019)
Cell Reports, Vol 27, Iss 6, Pp 1726-1741.e5 (2019)
SUMMARY Elucidating the mechanism of reprogramming is confounded by heterogeneity due to the low efficiency and differential kinetics of obtaining induced pluripotent stem cells (iPSCs) from somatic cells. Therefore, we increased the efficiency with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8277efacd5a3b35d25983b5acc930d23
http://europepmc.org/articles/PMC6555151
http://europepmc.org/articles/PMC6555151