Výsledky vyhledávání - "Amber N, Juba"

Akademický článek

Folic Acid Improves Parkin-Null Drosophila Phenotypes and Transiently Reduces Vulnerable Dopaminergic Neuron Mitochondrial Hydrogen Peroxide Levels and Glutathione Redox Equilibrium

Autor: Katherine L. Houlihan, Petros P. Keoseyan, Amber N. Juba, Tigran Margaryan, Max E. Voss, Alexander M. Babaoghli, Justin M. Norris, Greg J. Adrian, Artak Tovmasyan, Lori M. Buhlman

Publikováno v: Antioxidants, Vol 11, Iss 10, p 2068 (2022)

Loss-of-function parkin mutations cause oxidative stress and degeneration of dopaminergic neurons in the substantia nigra. Several consequences of parkin mutations have been described; to what degree they contribute to selective neurodegeneration rem

Externí odkaz: https://doaj.org/article/0a4f97b900d54a4d906ec63392368cf1

Zobrazit plný text záznamu

Akademický článek

3D quantification of autophagy activation and autophagosome-to-mitochondria recruitment in a Drosophila model of Parkinson’s disease

Autor: Susana J. Gutierrez-Luke, Amber N. Juba, Giulia Bertolin, Lori M. Buhlman

Publikováno v: STAR Protocols, Vol 2, Iss 2, Pp 100408- (2021)

Summary: Here, we describe a protocol for comprehensive quantification of autophagosome recruitment to mitochondria as an early step in mitophagy. Data collected using this protocol can be useful in the study of neurodegenerative disease, cancer, and

Externí odkaz: https://doaj.org/article/64de818d4b9c474f92c21cd61a5c727f

Zobrazit plný text záznamu

Optimization of translation enhancing element use to increase protein expression in a vaccinia virus system

Autor: Stephanie Minder, Amber N. Juba, James K. Jancovich, Brian P. Wellensiek, Bertram L. Jacobs, Amandeep Sidhu, Harold B. Richard

Publikováno v: The Journal of General Virology

Since the successful use of vaccinia virus (VACV) in the immunization strategies to eliminate smallpox, research has been focused on the development of recombinant VACV strains expressing proteins from various pathogens. Attempts at decreasing the si

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ad8d7e5a2b8b2035e011541fa81d1f4
https://pubmed.ncbi.nlm.nih.gov/34382930

Zobrazit plný text záznamu

Measuring Mitochondrial Hydrogen Peroxide Levels and Glutathione Redox Equilibrium in Drosophila Neuron Subtypes Using Redox-Sensitive Fluorophores and 3D Imaging

Autor: Lori M, Buhlman, Petros P, Keoseyan, Katherine L, Houlihan, Amber N, Juba

Publikováno v: Methods in molecular biology (Clifton, N.J.). 2276

Disruptions in mitochondrial redox activity are implicated in maladies ranging from those in which cells degenerate to those in which cell division is unregulated. This is not surprising given the pivotal role of mitochondria as ATP producers, reacti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d8082d452ae653475ed87b26645e43cc
https://pubmed.ncbi.nlm.nih.gov/36138297

Zobrazit plný text záznamu

Measuring Mitochondrial Hydrogen Peroxide Levels and Glutathione Redox Equilibrium in Drosophila Neuron Subtypes Using Redox-Sensitive Fluorophores and 3D Imaging

Autor: Kathryn Houlihan, Petros P Keoseyan, Amber N. Juba, Lori M. Buhlman

Publikováno v: Methods in Molecular Biology ISBN: 9781071612651

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c15a21346cd6e5516a92132ae4aed373
https://doi.org/10.1007/978-1-0716-1266-8_8

Zobrazit plný text záznamu

Exploring the Role of AUG Triplets in Human Cap-Independent Translation Enhancing Elements

Autor: Amber N. Juba, John C. Chaput, Brian P. Wellensiek

Publikováno v: Biochemistry
Biochemistry, vol 57, iss 44
Juba, AN; Chaput, JC; & Wellensiek, BP. (2018). Exploring the Role of AUG Triplets in Human Cap-Independent Translation Enhancing Elements. BIOCHEMISTRY, 57(44), 6308-6318. doi: 10.1021/acs.biochem.8b00785. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/9t34p7m1

Cap-independent translation is believed to play an important role in eukaryotic protein synthesis, but the mechanisms of ribosomal recruitment and translation initiation remain largely unknown. Messenger RNA display was previously used to profile the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::700d88ec5895e45efcfa8fbdabf32292
http://europepmc.org/articles/PMC6222554

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání