Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Amber L. Lacrosse"'
Publikováno v:
Pharmaceuticals, Vol 6, Iss 2, Pp 251-268 (2013)
Glutamate plays a pivotal role in drug addiction, and the N-methyl-D-aspartate (NMDA) glutamate receptor subtype serves as a molecular target for several drugs of abuse. In this review, we will provide an overview of NMDA receptor structure and funct
Externí odkaz:
https://doaj.org/article/19fe5b267ae64db28020b467e2c4b45d
Publikováno v:
Neural Plasticity, Vol 2012 (2012)
Adult-generated neurons in the dentate gyrus (DG) of the hippocampus play a role in various forms of learning and memory. However, adult born neurons in the DG, while still at an immature stage, exhibit unique electrophysiological properties and are
Externí odkaz:
https://doaj.org/article/2d398fa3184a4fc2bbe81c41325ddfbb
Publikováno v:
Neuropharmacology. 135:297-307
Cocaine use disorder is a chronically relapsing disease without FDA-approved treatments. Using a rodent model of cocaine relapse, we and others have previously demonstrated that the beta-lactam antibiotic ceftriaxone attenuates cue- and cocaine-prime
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ada37bbd09c49f457cdedcd62f3e80cb
https://doi.org/10.1016/j.neuropharm.2018.03.022
https://doi.org/10.1016/j.neuropharm.2018.03.022
Background Cocaine use disorder is characterized by compulsive drug-seeking that persists long into abstinence. Work using rodent models of cocaine addiction has found evidence for reversal learning deficits 21 days after non-contingent cocaine admin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4c6e5074070c859e79f8016051324a3
https://europepmc.org/articles/PMC6200584/
https://europepmc.org/articles/PMC6200584/
Autor:
Lori A. Knackstedt, Marian T. Sepulveda-Orengo, Amber L. LaCrosse, Robert E. McCullumsmith, Marek Schwendt, Kathryn J. Reissner, Sinead M. O’Donovan
Long-term treatment with ceftriaxone attenuates the reinstatement of cocaine seeking while increasing the function of the glutamate transporter 1 (GLT-1) and system xC- (Sxc) in the nucleus accumbens core (NAc). Sxc contributes the majority of nonsyn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b12547ff52c415adbd7a4cc7203c699c
Autor:
Brian T. Burrows, Nordia Mathews, Scott A. Wegner, Rachel M. Angulo, Sarah M. Himes, Amber L. LaCrosse, M. Foster Olive, Sara B. Taylor, Phoebe R. Conrad
Publikováno v:
Psychopharmacology. 232:251-258
Positive allosteric modulators (PAMs) of type 5 metabotropic glutamate receptors (mGluR5) exert pro-cognitive effects in animal models of various neuropsychiatric diseases. However, few studies to date have examined ability of mGluR5 PAMs to reverse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aeb91347e55c1515456503561194314c
https://doi.org/10.1007/s00213-014-3653-8
https://doi.org/10.1007/s00213-014-3653-8
Autor:
Amber L. LaCrosse, Michael Olive
Publikováno v:
CNS & Neurological Disorders - Drug Targets. 12:619-632
Schizophrenia affects approximately 1% of the world population, and the majority of pharmacologically based treatments for this disorder are ligands that interact with monoaminergic transmission. However, there is a wealth of evidence that various ne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cc463d014a46f8bfa2c99aee23539c4
https://doi.org/10.2174/1871527311312050010
https://doi.org/10.2174/1871527311312050010
Publikováno v:
Pharmaceuticals
Pharmaceuticals, Vol 6, Iss 2, Pp 251-268 (2013)
Pharmaceuticals, Vol 6, Iss 2, Pp 251-268 (2013)
Glutamate plays a pivotal role in drug addiction, and the N-methyl-D-aspartate (NMDA) glutamate receptor subtype serves as a molecular target for several drugs of abuse. In this review, we will provide an overview of NMDA receptor structure and funct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b858623f108bcd649963fcc89c946ea
https://doi.org/10.3390/ph6020251
https://doi.org/10.3390/ph6020251
Using the extinction-reinstatement model of cocaine relapse, we and others have demonstrated that the antibiotic ceftriaxone attenuates cue- and cocaine-primed reinstatement of cocaine-seeking. Reinstatement is contingent on the release of glutamate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cd6d48ed5b1872def8be24d8f9e0723
https://europepmc.org/articles/PMC4762719/
https://europepmc.org/articles/PMC4762719/
Autor:
Amber L. LaCrosse, Amin B. Kassam
Publikováno v:
Neuro-Oncology. 18:vi208-vi209
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0c02f99d10b526b6451bc7039969dd02
https://doi.org/10.1093/neuonc/now212.880
https://doi.org/10.1093/neuonc/now212.880