Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Amber L. H. Gray"'
Publikováno v:
Journal of the American Society for Mass Spectrometry. 34:472-483
Autor:
Miranda N. Limbach, Aleksandra Antevska, Damilola S. Oluwatoba, Amber L. H. Gray, Xian B. Carroll, Christina M. Hoffmann, Xiaoping Wang, Markus W. Voehler, Carlos A. Steren, Thanh D. Do
Publikováno v:
Journal of the American Chemical Society. 144(28)
An atomic view of a main aqueous conformation of cyclosporine A (CycA), an important 11-amino-acid macrocyclic immunosuppressant, is reported. For decades, it has been a grand challenge to determine the conformation of free CycA in an aqueous-like so
Autor:
Michael D. Karlstad, J. Jason Collier, Bryan A. Bogin, Zachary A. Levine, Susan J. Burke, Thanh D. Do, Samuel D Dupuy, Aleksandra Antevska, Amber L. H. Gray, Benjamin A. Link
Publikováno v:
Chemical Science
Despite being relatively benign and not an indicative signature of toxicity, fibril formation and fibrillar structures continue to be key factors in assessing the structure–function relationship in protein aggregation diseases. The inability to cap
Autor:
Amber L. H. Gray, Michael R. Sawaya, Debalina Acharyya, Jinchao Lou, Emery M. Edington, Michael D. Best, Rebecca A. Prosser, David S. Eisenberg, Thanh D. Do
Publikováno v:
Protein science : a publication of the Protein Society, vol 31, iss 3
Protein Sci
Protein Sci
Atomic structures of amyloid oligomers that capture the neurodegenerative disease pathology are essential to understand disease‐state causes and finding cures. Here we investigate the G6W mutation of the cytotoxic, hexameric amyloid model KV11. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34ddee26200d062b892bd6b30e398221
https://escholarship.org/uc/item/2jx5j3d7
https://escholarship.org/uc/item/2jx5j3d7
Autor:
Kristi Lazar Cantrell, Thanh D. Do, Grace E. Schonfeld, Aleksandra Antevska, Damilola S. Oluwatoba, Amber L. H. Gray
Publikováno v:
Analytical Chemistry. 92:11802-11808
Our knowledge of amyloid formation and cytotoxicity originating from self-assembly of α-helical peptides is incomplete. PSMα3 is the only system where high-resolution X-ray crystallography and toxi...
Autor:
Charles M, Russell, Katherine G, Schaefer, Andrew, Dixson, Amber L H, Gray, Robert J, Pyron, Daiane S, Alves, Nicholas, Moore, Elizabeth A, Conley, Ryan J, Schuck, Tommi A, White, Thanh D, Do, Gavin M, King, Francisco N, Barrera
Publikováno v:
eLife. 11
The fungus
Autor:
Amber L H, Gray, Carlos A, Steren, Isaac W, Haynes, Guillermo A, Bermejo, Filippo, Favretto, Markus, Zweckstetter, Thanh D, Do
Publikováno v:
The journal of physical chemistry. B. 125(5)
Falling outside of Lipinski's rule of five, macrocyclic drugs have accessed unique binding sites of their target receptors unreachable by traditional small molecules. Cyclosporin(e) A (CycA), an extensively studied macrocyclic natural product, is an
Autor:
Filippo Favretto, Markus Zweckstetter, Isaac W. Haynes, Carlos A. Steren, Guillermo A. Bermejo, Thanh D. Do, Amber L. H. Gray
Publikováno v:
The journal of physical chemistry / B 125(5), 1378-1391 (2021). doi:10.1021/acs.jpcb.0c11152
Falling outside of Lipinski's rule of five, macrocyclic drugs have accessed unique binding sites of their target receptors unreachable by traditional small molecules. Cyclosporin(e) A (CycA), an extensively studied macrocyclic natural product, is an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::752de8a345657c0f46c282f3b36a2f75
Autor:
Amber L H, Gray, Aleksandra, Antevska, Damilola S, Oluwatoba, Grace E, Schonfeld, Kristi L, Lazar Cantrell, Thanh D, Do
Publikováno v:
Analytical chemistry. 92(17)
Our knowledge of amyloid formation and cytotoxicity originating from self-assembly of α-helical peptides is incomplete. PSMα3 is the only system where high-resolution X-ray crystallography and toxicity data are available. Oligomers of multiple α-h
Autor:
Gray, Amber L. H., Sawaya, Michael R., Acharyya, Debalina, Lou, Jinchao, Edington, Emery M., Best, Michael D., Prosser, Rebecca A., Eisenberg, David S., Do, Thanh D.
Publikováno v:
Protein Science: A Publication of the Protein Society; Mar2022, Vol. 31 Issue 3, p716-727, 12p