The Delayed Neuropathological Consequences of Traumatic Brain Injury in a Community-Based Sample

Autor: Nadia Postupna, Shannon E. Rose, Laura E. Gibbons, Natalie M. Coleman, Leanne L. Hellstern, Kayla Ritchie, Angela M. Wilson, Eiron Cudaback, Xianwu Li, Erica J. Melief, Allison E. Beller, Jeremy A. Miller, Amber L. Nolan, Desiree A. Marshall, Rod Walker, Thomas J. Montine, Eric B. Larson, Paul K. Crane, Richard G. Ellenbogen, Edward S. Lein, Kristen Dams-O'Connor, C. Dirk Keene

Publikováno v: Frontiers in Neurology, Vol 12 (2021)

The late neuropathological effects of traumatic brain injury have yet to be fully elucidated, particularly with respect to community-based cohorts. To contribute to this critical gap in knowledge, we designed a multimodal neuropathological study, int

Externí odkaz: https://doaj.org/article/9d4ce0378ae94ea494bf39044a1146f3

Integrated multimodal cell atlas of Alzheimer’s disease

Autor: Mariano I. Gabitto, Kyle J. Travaglini, Victoria M. Rachleff, Eitan S. Kaplan, Brian Long, Jeanelle Ariza, Yi Ding, Joseph T. Mahoney, Nick Dee, Jeff Goldy, Erica J. Melief, Krissy Brouner, Jazmin Campos, John Campos, Ambrose J. Carr, Tamara Casper, Rushil Chakrabarty, Michael Clark, Jonah Cool, Nasmil J. Valera Cuevas, Rachel Dalley, Martin Darvas, Song-Lin Ding, Tim Dolbeare, Christine L. Mac Donald, Tom Egdorf, Luke Esposito, Rebecca Ferrer, Rohan Gala, Amanda Gary, Jessica Gloe, Nathan Guilford, Junitta Guzman, Daniel Hirschstein, Windy Ho, Tim Jarksy, Nelson Johansen, Brian E. Kalmbach, Lisa M. Keene, Sarah Khawand, Mitch Kilgore, Amanda Kirkland, Michael Kunst, Brian R. Lee, Jocelin Malone, Zoe Maltzer, Naomi Martin, Rachel McCue, Delissa McMillen, Emma Meyerdierks, Kelly P. Meyers, Tyler Mollenkopf, Mark Montine, Amber L. Nolan, Julie Nyhus, Paul A. Olsen, Maiya Pacleb, Nicholas Peña, Thanh Pham, Christina Alice Pom, Nadia Postupna, Augustin Ruiz, Aimee M. Schantz, Nadiya V. Shapovalova, Staci A. Sorensen, Brian Staats, Matt Sullivan, Susan M. Sunkin, Carol Thompson, Michael Tieu, Jonathan Ting, Amy Torkelson, Tracy Tran, Ming-Qiang Wang, Jack Waters, Angela M. Wilson, David Haynor, Nicole Gatto, Suman Jayadev, Shoaib Mufti, Lydia Ng, Shubhabrata Mukherjee, Paul K. Crane, Caitlin S. Latimer, Boaz P. Levi, Kimberly Smith, Jennie L. Close, Jeremy A. Miller, Rebecca D. Hodge, Eric B. Larson, Thomas J. Grabowski, Michael Hawrylycz, C. Dirk Keene, Ed S. Lein

Alzheimer’s disease (AD) is the most common cause of dementia in older adults. Neuropathological and imaging studies have demonstrated a progressive and stereotyped accumulation of protein aggregates, but the underlying molecular and cellular mecha

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3819862faf9d0f4384328a779b869e30
https://doi.org/10.1101/2023.05.08.539485

Protocol for the Systematic Fixation, Circuit-Based Sampling, and Qualitative and Quantitative Neuropathological Analysis of Human Brain Tissue

Autor: Caitlin S, Latimer, Erica J, Melief, Jeanelle, Ariza-Torres, Kim, Howard, Amanda R, Keen, Lisa M, Keene, Aimee M, Schantz, Trevor M, Sytsma, Angela M, Wilson, Thomas J, Grabowski, Martin, Darvas, Kristen Dams, O'Connor, Amber L, Nolan, Brian L, Edlow, Christine L, Mac Donald, C Dirk, Keene

Publikováno v: Methods in molecular biology (Clifton, N.J.). 2561

Human brain tissue has long been a critical resource for neuroanatomy and neuropathology, but with the advent of advanced imaging and molecular sequencing techniques, it has become possible to use human brain tissue to study, in great detail, the str

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::1109f3b350971f9791af3c46290150d2
https://pubmed.ncbi.nlm.nih.gov/36399262

Tractography-Pathology Correlations in Traumatic Brain Injury: A TRACK-TBI Study

Autor: Amber L. Nolan, Ramon Diaz-Arrastia, Amy J. Markowitz, Allison Stevens, Bram R. Diamond, Geoffrey T. Manley, Cathrine Petersen, Brian L. Edlow, Bruce Fischl, Pratik Mukherjee, Sonia Jain, Andre van der Kouwe, Ruopeng Wang, Daniel P. Perl, C. Dirk Keene, Diego Iacono, Christine L. Mac Donald

Publikováno v: Journal of neurotrauma, vol 38, iss 12
J Neurotrauma

Diffusion tractography MRI can infer changes in network connectivity in patients with traumatic brain injury (TBI), but pathological substrates of disconnected tracts have not been well-defined due to a lack of high-resolution imaging with histopatho

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c814433911f079e675144f7ed0f527c6
https://escholarship.org/uc/item/68d9g4vk