Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Amber J. Castellanos"'
Autor:
Amy R. Williams, Sabina Bashir, Davina A. Lewis, Robert R Hoopes, Michael G. Kemp, Michael P. Markey, Jonathan Weyerbacher, Mathew M. Loesch, Kenneth Y. Tsai, David H. Southern, Dan F. Spandau, Matthew Kuhar, Jeffrey J. Wargo, Christina Knisely, Elizabeth Cates, Sunil S. Tholpady, Jeffrey B. Travers, Amber J. Castellanos, Angela Zhang, Craig A Rohan, Ryan D. Gabbard, Roy Chen
Publikováno v:
J Clin Invest
BACKGROUND: The loss of insulin-like growth factor 1 (IGF-1) expression in senescent dermal fibroblasts during aging is associated with an increased risk of nonmelanoma skin cancer (NMSC). We tested how IGF-1 signaling can influence photocarcinogenes
Autor:
Mae Alexandra Carpenter, Rebekah J. Hutcherson, Amber J. Castellanos, Abdulrahman M.M. Alkawar, Michael G. Kemp, Mariyyah A.O. Madkhali, Ron Michael Johnson, Michael Bottomley
Publikováno v:
Photochem Photobiol
The tumor suppressor protein p53 limits mutagenesis in response to ultraviolet-B (UVB) light exposure by activating the transcription of genes that mitigate the damaging effects of UVB radiation on DNA. Because most nonmelanoma skin cancers (NMSCs) o