Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Amber I. Haugeto"'
Autor:
Yuriy A. Abramov, John C. Murray, Leonard Buckbinder, Ellen R. Laird, Matthew R. Reese, Kleinman Edward F, Yves A. Chantigny, Matthew David Wessel, E. D. Salter, Sue A. Yocum, Morgan Bradley P, Ralph P. Robinson, Jean Schaefer, Amber I. Haugeto, Jon Bordner, Patricia A. McNiff, Michele L. Millham
Publikováno v:
Journal of Medicinal Chemistry. 52:1731-1743
As exemplified by the lead compound 2, octahydrophenanthrene-2,7-diol analogues exhibit the profile of a pathway-selective or "dissociated" agonist of the glucocorticoid receptor (GR), retaining the potent activity that glucocorticoids have for trans
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b7be2568bff2da7c37818c84b398c67
https://doi.org/10.1021/jm801512v
https://doi.org/10.1021/jm801512v
Autor:
Christopher S. Jones, Jennifer L. Liras, Sue A. Yocum, Joel R. Hardink, Shang-Poa P. Chang, Julian Blagg, Lilli Ann Wolf-Gouveia, Ralph P. Robinson, Mark C. Noe, Peter G. Mitchell, Nancy C. Elliott, Amber I. Haugeto, Jayvardhan Pandit, R. J. Griffiths, Ellen R. Laird, Lawrence A. Reiter, James D. Eskra, Marcie L. Vaughn-Bowser, Chakrapani Subramanyam, James T. Downs, Lori L. Lopresti-Morrow, Dennis E. Danley
Publikováno v:
Bioorganicmedicinal chemistry letters. 15(7)
Through the use of computational modeling, a series of pyrimidinetrione-based inhibitors of MMP-13 was designed based on a lead inhibitor identified through file screening. Incorporation of a biaryl ether moiety at the C-5 position of the pyrimidinet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c1b93251818383c7c6286b45657c782
https://pubmed.ncbi.nlm.nih.gov/15780611
https://pubmed.ncbi.nlm.nih.gov/15780611
Autor:
Ralph P. Robinson, Leonard Buckbinder, Amber I. Haugeto, Patricia A. McNiff, Michele L. Millham, Matthew R. Reese, Jean F. Schaefer, Yuriy A. Abramov, Jon Bordner, Yves A. Chantigny, Edward F. Kleinman, Ellen R. Laird, Bradley P. Morgan, John C. Murray, Eben D. Salter, Matthew D. Wessel, Sue A. Yocum
Publikováno v:
Journal of Medicinal Chemistry; Mar2009, Vol. 52 Issue 6, p1731-1743, 13p