Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Amber Glanfield"'
Autor:
Amber Glanfield, Donald P McManus, Danielle J Smyth, Erica M Lovas, Alex Loukas, Geoffrey N Gobert, Malcolm K Jones
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 4, Iss 11, p e884 (2010)
BACKGROUND: Iron has an integral role in numerous cellular reactions and is required by virtually all organisms. In physiological conditions, iron is abundant in a largely insoluble ferric state. Ferric reductases are an essential component of iron u
Externí odkaz:
https://doaj.org/article/d7b2ea59f98d4c45af8f16a9ab7e5e4d
Autor:
Amber Glanfield
Iron is a trace element required for a range of metabolic reactions in virtually all living organisms. Studies of prokaryotes, plants, yeast, and vertebrates have established detailed information on iron uptake and the role iron plays in metabolic pr
Externí odkaz:
http://espace.library.uq.edu.au/view/UQ:205499
Autor:
D. Hoang-Le, Nathan Subramaniam, Grant A. Ramm, M. Fernandez-Rojo, Amber Glanfield, A. G. Burgess
Publikováno v:
Journal of Gastroenterology and Hepatology. 29:124-139
Hepatic stellate cells (HSCs) are responsible for collagen deposition leading to fibrosis following liver injury/inflammation. Serum levels of the acute phase protein ferritin are elevated in inflammation and act as an indicator of disease severity i
Publikováno v:
Critical Reviews in Oncogenesis. 18:391-407
Iron is an essential co-factor for life; however, a physiologically optimal balance is critical. Too much or too little iron can have detrimental effects on human health. In this article, we explore the relationships between iron and hepatocellular c
Autor:
Geoffrey N. Gobert, Sujeevi Nawaratna, Amber Glanfield, Leigh Schulte, Donald P. McManus, Malcolm K. Jones
Publikováno v:
Experimental Parasitology. 127:768-776
Members of the zinc-regulated transporter/iron-regulated transporter-like protein (ZIP) family of proteins transport metal ions across cell membranes. Genes encoding ZIPs are present in the genomes of schistosomes. Here, we describe molecular charact
Autor:
Yuesheng Li, Malcolm K. Jones, Danielle I. Stanisic, Paul B. Bartley, Amber Glanfield, Mary Duke, Donald P. McManus
Publikováno v:
The American Journal of Tropical Medicine and Hygiene. 78:929-935
Artemether (ART) is a well-described antimalarial with efficacy against juvenile schistosomes, with 7-day-old schistosomula being particularly susceptible. Both ART-affected worms and parasites developing from irradiated cercariae die at similar time
Publikováno v:
Trends in Parasitology
ResearcherID
ResearcherID
Parasites, as with the vast majority of organisms, are dependent on iron. Pathogens must compete directly with the host for this essential trace metal, which is sequestered within host proteins and inorganic chelates. Not surprisingly, pathogenic pro
Autor:
Malcolm K. Jones, Geoffrey N. Gobert, Donald P. McManus, Danielle J. Smyth, Amber Glanfield, Alex Loukas, Erica Lovas
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 4, Iss 11, p e884 (2010)
PLoS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases
Background Iron has an integral role in numerous cellular reactions and is required by virtually all organisms. In physiological conditions, iron is abundant in a largely insoluble ferric state. Ferric reductases are an essential component of iron up
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4056c609ba19605cdb1b7bdc1b7784c
https://eprints.gla.ac.uk/158650/1/158650.pdf
https://eprints.gla.ac.uk/158650/1/158650.pdf
Publikováno v:
Parasites & Vectors, Vol 3, Iss 1, p 108 (2010)
Parasites & Vectors
Parasites & Vectors
Hemoparasites, like malaria and schistosomes, are constantly faced with the challenges of storing and detoxifying large quantities of heme, released from their catabolism of host erythrocytes. Heme is an essential prosthetic group that forms the reac
Autor:
Luke Moertel, Donald P. McManus, Malcolm K. Jones, Sabina I. Belli, Amber Glanfield, Geoffrey N. Gobert, Padma Sivadorai
Publikováno v:
The International Journal of Biochemistry & Cell Biology
Iron (Fe) is an important trace element found in nearly all organisms, and is used as a cofactor in many biological reactions. One role for Fe in some invertebrates is in stabilization of extracellular matrices. The human blood fluke, Schistosoma jap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc9de041f605c309eba7bc24237c5f54
https://hdl.handle.net/10453/3753
https://hdl.handle.net/10453/3753