Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Amber Eliason"'
Autor:
Ran Wang, Sean Campbell, Mohammed Amir, Sarah A. Mosure, Molly A. Bassette, Amber Eliason, Mark S. Sundrud, Theodore M. Kamenecka, Laura A. Solt
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
Unlike RORα, which has been thought to be somewhat redundant, RORγt has been well characterized in its function and contribution to the development of Th17 cells. Here the authors show that RORα is important in Th17 differentiation and that RORα
Externí odkaz:
https://doaj.org/article/73087ff786264483a5b440dbda18a0f9
Autor:
Xiangsheng Huang, HaJeung Park, Deborah Schady, Alexander Rodriguez-Palacios, Guohui Wang, Mei Lan Chen, Yujin Liu, Casey T. Weaver, Douglas J. Kojetin, Amber Eliason, David D. Moore, Jinsai Shang, Matthew E. Pipkin, Huitian Diao, Blake Frey, Laura A. Solt, Mark S. Sundrud, Courtney Hegner, Hongtao Wang, Sarah A. Mosure
Publikováno v:
Nature
Bile acids are lipid-emulsifying metabolites synthesized in hepatocytes and maintained in vivo through enterohepatic circulation between the liver and small intestine1. As detergents, bile acids can cause toxicity and inflammation in enterohepatic ti
Autor:
Amber Eliason, Laura A. Solt, Ran Wang, Sarah A. Mosure, Sean Campbell, Mohammed Amir, Theodore M. Kamenecka, Mark S. Sundrud, Molly A. Bassette
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
Full development of IL-17 producing CD4+ T helper cells (TH17 cells) requires the transcriptional activity of both orphan nuclear receptors RORα and RORγt. However, RORα is considered functionally redundant to RORγt; therefore, the function and t
Autor:
Rita Fuerst, Jun Yong Choi, Anna M. Knapinska, Michael D. Cameron, Claudia Ruiz, Amber Eliason, Mark S. Sundrud, Gregg B. Fields, William R. Roush
Publikováno v:
SSRN Electronic Journal.
Autor:
Rita Fuerst, Jun Yong Choi, Anna M. Knapinska, Michael D. Cameron, Claudia Ruiz, Amber Eliason, Mark S. Sundrud, Gregg B. Fields, William R. Roush
Publikováno v:
SSRN Electronic Journal.
Autor:
Alexander Rodriguez-Palacios, Mei Lan Chen, Yujin Liu, Douglas J. Kojetin, Courtney Hegner, Deborah Schady, Guohui Wang, Xiangsheng Huang, Casey T. Weaver, HaJeung Park, Sarah A. Mosure, Mark S. Sundrud, Blake Frey, Jinsai Shang, Amber Eliason, Matthew E. Pipkin, Laura A. Solt, Hongtao Wang, David D. Moore
Bile acids (BAs) are lipid emulsifying metabolites synthesized in hepatocytes and maintained in vivo through enterohepatic circulation between the liver and small intestine1. As detergents, BAs can cause toxicity and inflammation in enterohepatic tis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b953c84c393fbb526be152c12e9718e8
https://doi.org/10.1101/2020.07.30.229864
https://doi.org/10.1101/2020.07.30.229864
Autor:
Mei Lan Chen, Adam J. Getzler, Amy Sun, Matthew E. Pipkin, Kayla M. Mendez, Sang Yong Kim, Huitian Diao, Clever Mukori, Sergei B. Koralov, Nelson E Bruno, Wei Cao, Shanel Tsuda, Amber Eliason, Mark S. Sundrud
Publikováno v:
The Journal of Experimental Medicine
MDR1 is considered a dedicated drug efflux pump in tumor cells. Chen et al. show that endogenous MDR1 expression in CD8+ T cells is required for immunity to pathogens, revealing new concepts in cell-mediated immunity and informing use of MDR1 inhibit
Autor:
Ran, Wang, Sean, Campbell, Mohammed, Amir, Sarah A, Mosure, Molly A, Bassette, Amber, Eliason, Mark S, Sundrud, Theodore M, Kamenecka, Laura A, Solt
Publikováno v:
Nature Communications
Full development of IL-17 producing CD4+ T helper cells (TH17 cells) requires the transcriptional activity of both orphan nuclear receptors RORα and RORγt. However, RORα is considered functionally redundant to RORγt; therefore, the function and t
Autor:
Laura A Solt, Ran Wang, Mohammed Amir, Sweena Chaudhari, Sean Campbell, Molly B Bassette, Amber Eliason, Mark S Sundrud, Theodore Kamenecka
Publikováno v:
The Journal of Immunology. 202:68.11-68.11
While RORγt has been well characterized as the lineage defining transcription factor for TH17 cell development, TH17 cells are not absent in Rorc-deficient mice, suggesting other factors may be required. RORα, a close family member of RORγt, is al