Výsledky vyhledávání - "Amber E. Boyatzis"

Oxidation of cysteine 34 of plasma albumin as a biomarker of oxidative stress

Autor: Marisa N. Duong, Peter G. Arthur, Zi Xiang Lim, Alice Vrielink, Emily Golden, Amber E. Boyatzis, Paul A. Fournier

Publikováno v: Free Radical Research. 54:91-103

Introduction: In order to better understand the physiological and pathophysiological roles of reactive oxygen species (ROS), multiple blood and urine biomarkers of oxidative stress have been develo...

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1879afb774726f0dddabc77461776cf1
https://doi.org/10.1080/10715762.2019.1708347

Zobrazit plný text záznamu

Plný text ve formátu HTML

Isotope-Coded Maleimide Affinity Tags for Proteomics Applications

Autor: Matthew J. Piggott, Mark C. Walkey, Marisa N. Duong, Peter G. Arthur, Adam P. Wdowiak, Rohan D. Joyce, Gareth L. Nealon, Amber E. Boyatzis

Publikováno v: Bioconjugate chemistry. 32(8)

Isotope-coded affinity tags (ICATs) are valuable tools for mass spectrometry-based quantitative proteomics, in particular, for comparison of protein (cysteine-residue) thiol oxidation state in normal, stressed, and diseased tissue. However, the iodoa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67e02459eb49d83fd08d4ff35d2d5d33
https://pubmed.ncbi.nlm.nih.gov/34160215

Zobrazit plný text záznamu

Limiting the Hydrolysis and Oxidation of Maleimide–Peptide Adducts Improves Detection of Protein Thiol Oxidation

Autor: Scott Bringans, Amber E. Boyatzis, Peter G. Arthur, Marisa N. Duong, Matthew J. Piggott, Richard J. Lipscombe

Publikováno v: Journal of Proteome Research. 16:2004-2015

Oxidative stress, caused by reactive oxygen and nitrogen species (RONS), is important in the pathophysiology of many diseases. A key target of RONS is the thiol group of protein cysteine residues. Because thiol oxidation can affect protein function,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f3571a176e3097467a73d7cd8975d07
https://doi.org/10.1021/acs.jproteome.6b01060

Zobrazit plný text záznamu

Levels of inflammation and oxidative stress, and a role for taurine in dystropathology of the Golden Retriever Muscular Dystrophy dog model for Duchenne Muscular Dystrophy

Autor: Peter G. Arthur, Miranda D. Grounds, Amber E. Boyatzis, Jessica R. Terrill, Marisa N. Duong, Rufus Turner, Anthony J. Kettle, Caroline Le Guiner

Publikováno v: Redox Biology, Vol 9, Iss C, Pp 276-286 (2016)
Redox Biology

Duchenne Muscular Dystrophy (DMD) is a fatal skeletal muscle wasting disease presenting with excessive myofibre necrosis and increased inflammation and oxidative stress. In the mdx mouse model of DMD, homeostasis of the amino acid taurine is altered,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23acd2e8549bc1dba64a7f52e4413240

Zobrazit plný text záznamu

Treatment with the cysteine precursor l-2-oxothiazolidine-4-carboxylate (OTC) implicates taurine deficiency in severity of dystropathology in mdx mice

Autor: Amber E. Boyatzis, Peter G. Arthur, Jessica R. Terrill, Miranda D. Grounds

Publikováno v: The international journal of biochemistrycell biology. 45(9)

Oxidative stress has been implicated in the pathology of the lethal skeletal muscle disease Duchenne muscular dystrophy (DMD), and various antioxidants have been investigated as a potential therapy. Recently, treatment of the mdx mouse model for DMD

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a5fd5649109de2b90c7297e782ece97
https://pubmed.ncbi.nlm.nih.gov/23892094

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání