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pro vyhledávání: '"Amber Afzal"'
Autor:
Amber Afzal, Zobia Afzal, Sophia Bizink, Amanda Davis, Sara Makahleh, Yara Mohamed, Salvatore J. Coniglio
Publikováno v:
Current Issues in Molecular Biology, Vol 46, Iss 8, Pp 7795-7811 (2024)
Glioblastoma multiforme (GBM) is one of the deadliest human cancers with very limited treatment options available. The malignant behavior of GBM is manifested in a tumor which is highly invasive, resistant to standard cytotoxic chemotherapy, and stro
Externí odkaz:
https://doaj.org/article/c0702ad7c25842f5b694557ce6ba3023
Autor:
Martin W. Schoen, Kenneth R. Carson, Suhong Luo, Brian F. Gage, Ang Li, Amber Afzal, Kristen M. Sanfilippo
Publikováno v:
Research and Practice in Thrombosis and Haemostasis, Vol 4, Iss 7, Pp 1203-1210 (2020)
Abstract Background In multiple myeloma, venous thromboembolism (VTE) is common, and treatments for myeloma, such as lenalidomide, increase the risk of thrombosis while improving survival. The association between VTE and survival is not well known. O
Externí odkaz:
https://doaj.org/article/35c5a7b44b4f44ac9a45101124ca3a28
Publikováno v:
Blood Advances.
Publikováno v:
Clinical Lymphoma Myeloma and Leukemia. 20:e937-e943
Background We studied the effect of statins on mortality in a nationally representative sample of patients with multiple myeloma, and explored the benefit of statins in a subgroup of patients treated with novel agents. Methods Patients diagnosed with
Autor:
Amber Afzal, Brian F. Gage, Luo Suhong, Martin W. Schoen, Kevin Korenblat, Kristen M. Sanfilippo
Publikováno v:
J Thromb Haemost
BACKGROUND: Patients with chronic liver disease (CLD) often present with an elevated International Normalized Ratio (INR). Although elevated INR reflects a higher risk of hemorrhage among warfarin users, its clinical significance in CLD patients is l
Publikováno v:
Transfusion. 60:351-357
Background Two extracorporeal photopheresis (ECP) instruments, the CELLEX and the UVARXTS are currently being used "off-label" in the US for treatment of graft versus host disease (GVHD). Our study compared the performance of the two instruments in t
Publikováno v:
Journal of Clinical Oncology. 40:e18762-e18762
e18762 Background: Prognostication of patients with myelodysplastic syndromes (MDS) using IPSS-R is not possible in administrative database analysis. In 2014, a claims-based prognostic scoring system, the SEER-Medicare MDS Risk Score (SMMRS) was deve
Publikováno v:
Journal of Clinical Oncology. 40:e19063-e19063
e19063 Background: Statins can inhibit cholesterol synthesis through inhibition of mevalonic acid synthesis, and reduce prenylation of proteins involved in tumor growth. Their anti-neoplastic potential has been explored for many malignancies (e.g., m
Autor:
Ang Li, Suhong Luo, Kenneth R. Carson, Amber Afzal, Martin W. Schoen, Brian F. Gage, Kristen M. Sanfilippo
Publikováno v:
Research and Practice in Thrombosis and Haemostasis
Research and Practice in Thrombosis and Haemostasis, Vol 4, Iss 7, Pp 1203-1210 (2020)
Research and Practice in Thrombosis and Haemostasis, Vol 4, Iss 7, Pp 1203-1210 (2020)
Background In multiple myeloma, venous thromboembolism (VTE) is common, and treatments for myeloma, such as lenalidomide, increase the risk of thrombosis while improving survival. The association between VTE and survival is not well known. Objectives
Publikováno v:
Blood. 136:4-5
Background: Elevated INR values are common among patients with chronic liver disease (CLD), and signify a decrease in the synthesis of clotting factors II, V, VII, IX and X. Preclinical evidence suggests that the decrease in these factors is balanced