Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Amaya Puig-Kroger"'
Autor:
Esther Caparrós, Oriol Juanola, Isabel Gómez-Hurtado, Amaya Puig-Kroger, Paula Piñero, Pedro Zapater, Raquel Linares, Fabián Tarín, Sebastián Martínez-López, Jordi Gracia-Sancho, José M. González-Navajas, Rubén Francés
Publikováno v:
Cells, Vol 9, Iss 5, p 1227 (2020)
Hepatic immune function is compromised during cirrhosis. This study investigated the immune features of liver sinusoidal endothelial cells (LSECs) in two experimental models of cirrhosis. Dendritic cells, hepatic macrophages, and LSECs were isolated
Externí odkaz:
https://doaj.org/article/bb98d19e0bff42cbb7320aff21933b7a
Autor:
Israel Ríos, Baltasar López-Navarro, Mónica Torres-Torresano, Blanca Soler Palacios, Miriam Simón-Fuentes, Ángeles Domínguez-Soto, Ittai B. Muller, Gerrit Jansen, Ángel L. Corbí, Amaya Puig-Kröger
Publikováno v:
Journal of Innate Immunity, Pp 1-14 (2022)
Methotrexate (MTX) is an antifolate drug used as a chemotherapeutic agent for acute lymphoblastic leukemia, where MTX improves patients’ prognosis. Macrophage reprogramming is being increasingly assessed as an antitumor therapeutic strategy. Howeve
Externí odkaz:
https://doaj.org/article/2e2410ee239c488892b15234b443fcdb
Autor:
Arturo González de la Aleja, Cristina Herrero, Mónica Torres-Torresano, Juan Vladimir de la Rosa, Bárbara Alonso, Enrique Capa-Sardón, Ittai B. Muller, Gerrit Jansen, Amaya Puig-Kröger, Miguel A. Vega, Antonio Castrillo, Ángel L. Corbí
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Liver X Receptors (LXR) control cholesterol metabolism and exert anti-inflammatory actions but their contribution to human macrophage polarization remains unclear. The LXR pathway is enriched in pro-inflammatory macrophages from rheumatoid arthritis
Externí odkaz:
https://doaj.org/article/74a9cd2489134bd39bba68edb1a38025
Autor:
Sara Fuentelsaz-Romero, Celia Barrio-Alonso, Raquel García Campos, Mónica Torres Torresano, Ittai B. Muller, Ana Triguero-Martínez, Laura Nuño, Alejandro Villalba, Rosario García-Vicuña, Gerrit Jansen, María-Eugenia Miranda-Carús, Isidoro González-Álvaro, Amaya Puig-Kröger
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
The identification of “trained immunity/tolerance” in myeloid cells has changed our perception of the performance of monocytes and macrophages during inflammatory and immune responses. Pemetrexed (PMX) and methotrexate (MTX) are blockers of the o
Externí odkaz:
https://doaj.org/article/0c17ff55e2564e3295c528665d899119
Autor:
Sara Fuentelsaz-Romero, Andrea Cuervo, Lizbeth Estrada-Capetillo, Raquel Celis, Raquel García-Campos, Julio Ramírez, Sergi Sastre, Rafael Samaniego, Amaya Puig-Kröger, Juan D. Cañete
Publikováno v:
Frontiers in Immunology, Vol 11 (2021)
Background and AimsGM-CSF-dependent macrophage polarization has been demonstrated in rheumatoid arthritis (RA). Our aim was to seek diagnostic/prognostic biomarkers for undifferentiated arthritis (UA) by analyzing GM-CSF expression and source, macrop
Externí odkaz:
https://doaj.org/article/f963dba0a75f43d589c8b4d1e93ba7dd
Autor:
Ramon M. Rodriguez, Beatriz Suarez-Alvarez, Jose L. Lavín, Alex M. Ascensión, Monika Gonzalez, Juan J. Lozano, Aroa B. Raneros, Paula D. Bulnes, Jose R. Vidal-Castiñeira, Covadonga Huidobro, Cristina Martin-Martin, Ana B. Sanz, Marta Ruiz-Ortega, Amaya Puig-Kröger, Angel L. Corbí, Marcos J. Araúzo-Bravo, Ana M. Aransay, Carlos Lopez-Larrea
Publikováno v:
Cell Reports, Vol 29, Iss 4, Pp 860-872.e5 (2019)
Summary: In recent years, the macrophage colony-stimulating factor (M-CSF) and granulocyte-macrophage CSF (GM-CSF) cytokines have been identified as opposing regulators of the inflammatory program. However, the two cytokines are simultaneously presen
Externí odkaz:
https://doaj.org/article/69b31ac581ed459390e887cfe1dc0c24
Autor:
Rafael Samaniego, Ángeles Domínguez-Soto, Manohar Ratnam, Takami Matsuyama, Paloma Sánchez-Mateos, Ángel L. Corbí, Amaya Puig-Kröger
Publikováno v:
Cells, Vol 9, Iss 6, p 1445 (2020)
As macrophages exhibit a huge functional plasticity under homeostasis and pathological conditions, they have become a therapeutic target for chronic inflammatory diseases. Hence, the identification of macrophage subset-specific markers is a requisite
Externí odkaz:
https://doaj.org/article/406d4dac6a5e4b6680290e20c23de92c
Autor:
Concha Nieto, Rafael Bragado, Cristina Municio, Elena Sierra-Filardi, Bárbara Alonso, María M. Escribese, Jorge Domínguez-Andrés, Carlos Ardavín, Antonio Castrillo, Miguel A. Vega, Amaya Puig-Kröger, Angel L. Corbí
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
GM-CSF promotes the functional maturation of lung alveolar macrophages (A-MØ), whose differentiation is dependent on the peroxisome proliferator-activated receptor gamma (PPARγ) transcription factor. In fact, blockade of GM-CSF-initiated signaling
Externí odkaz:
https://doaj.org/article/d299462ea31449ff9660b4339cdd9b88
Autor:
María-Belén Bautista-Caro, Eugenio de Miguel, Diana Peiteado, Chamaida Plasencia-Rodríguez, Alejandro Villalba, Irene Monjo-Henry, Amaya Puig-Kröger, Paloma Sánchez-Mateos, Emilio Martín-Mola, María-Eugenia Miranda-Carús
Publikováno v:
PLoS ONE, Vol 12, Iss 7, p e0180726 (2017)
Our objective was to study the frequency of circulating CD19+CD24hiCD38hi B cells (Breg) in AS patients. To this end, peripheral blood was drawn from AS patients naïve for TNF blockers (AS/nb) (n = 42) and healthy controls (HC) (n = 42). Six patient
Externí odkaz:
https://doaj.org/article/0ed5f09979824be3a835a922ba7f3443
Autor:
María-Belén Bautista-Caro, Irene Arroyo-Villa, Concepción Castillo-Gallego, Eugenio de Miguel, Diana Peiteado, Chamaida Plasencia-Rodríguez, Alejandro Villalba, Paloma Sánchez-Mateos, Amaya Puig-Kröger, Emilio Martín-Mola, María-Eugenia Miranda-Carús
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e107086 (2014)
Follicular helper T cells (Tfh), localized in lymphoid organs, promote B cell differentiation and function. Circulating CD4 T cells expressing CXCR5, ICOS and/or PD-1 are counterparts of Tfh. Three subpopulations of circulating CD4+CXCR5+ cells have
Externí odkaz:
https://doaj.org/article/3fd4e9206cfe4626843910fc27d6e2c0