Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Amaya Montserat Austrich-Olivares"'
Autor:
Héctor Alonso Romero-Sánchez, Gabriela Garza-Mouriño, Liliana Mendieta, Marcela Ivonne Benítez-Díaz Mirón, Beatriz Godínez-Chaparro, Arrigo Coen, Amaya Montserat Austrich-Olivares
Publikováno v:
European Journal of Pharmacology. 869:172814
Pain is the non-motor symptom with the highest prevalence in patients with Parkinson's Disease (PD) affecting 40–85%. This study aimed to investigate the development of tactile allodynia and mechanical hyperalgesia after the nigrostriatal dopaminer
Autor:
Bernhard Wünsch, Sergio Hidalgo-Figueroa, Héctor Torres-Gómez, Emanuel Hernández-Núñez, Beatriz Godínez-Chaparro, Dirk Schepmann, Amaya Montserat Austrich-Olivares, Gabriel Navarrete-Vázquez, Samuel Estrada-Soto
Publikováno v:
Biomedicinepharmacotherapy = Biomedecinepharmacotherapie. 79
Compound 2-(3,4-dichlorophenoxy)-N-(2-morpholin-4-ylethyl)acetamide (1) was designed, prepared and the in vitro binding evaluation against σ1 and σ2 receptors was measured. Compound 1 showed high σ1 receptor affinity (Ki=42 nM) and it was 36-times