Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Amaya I Wolf"'
Autor:
Brian J Laidlaw, Vilma Decman, Mohammed-Alkhatim A Ali, Michael C Abt, Amaya I Wolf, Laurel A Monticelli, Krystyna Mozdzanowska, Jill M Angelosanto, David Artis, Jan Erikson, E John Wherry
Publikováno v:
PLoS Pathogens, Vol 9, Iss 3, p e1003207 (2013)
Seasonal epidemics of influenza virus result in ∼36,000 deaths annually in the United States. Current vaccines against influenza virus elicit an antibody response specific for the envelope glycoproteins. However, high mutation rates result in the e
Externí odkaz:
https://doaj.org/article/994408610fd6416fb404109389d65902
Autor:
Amaya I Wolf, Krystyna Mozdzanowska, Katie L Williams, David Singer, Monique Richter, Ralf Hoffmann, Andrew J Caton, Laszlo Otvos, Jan Erikson
Publikováno v:
PLoS ONE, Vol 6, Iss 12, p e28445 (2011)
The extracellular domain of the influenza A virus protein matrix protein 2 (M2e) is remarkably conserved between various human isolates and thus is a viable target antigen for a universal influenza vaccine. With the goal of inducing protection in mul
Externí odkaz:
https://doaj.org/article/f73533fac96b4b488c6d21521ca56604
Autor:
Craig Tipple, Naiem S. Moiemen, Chris Ioannou, Marcella Paglione, Summer Goodson, Kirsty McGee, Donna O'Neil, Catherine L. Winder, Carly Barnett, Amaya I. Wolf, Amy L. Bamford, Warwick B. Dunn, Janet M. Lord, Scott Berger
Publikováno v:
Burns Open, Vol 4, Iss 3, Pp 94-102 (2020)
Objectives: Severe thermal injury (TI) has been associated with increased intestinal permeability and the development of multiple organ dysfunction syndrome. The aim of this case series from a prospective, longitudinal study is to describe the impact
Externí odkaz:
https://doaj.org/article/3c0b20ae1a2b46dc8a1c99203aeebaf3
Autor:
Scott B. Berger, Warwick B. Dunn, Amaya I. Wolf, Catherine L. Winder, Kirsty McGee, Carly Barnett, Naiem Moiemen, Marcella Paglione, Amy Bamford, Donna M. O'Neil, Chris Ioannou, Craig Tipple, Janet M. Lord, Summer Goodson
Publikováno v:
Burns Open, Vol 4, Iss 3, Pp 94-102 (2020)
Objectives Severe thermal injury (TI) has been associated with increased intestinal permeability and the development of multiple organ dysfunction syndrome. The aim of this case series from a prospective, longitudinal study is to describe the impact
Autor:
Zhang Wang, James R. Brown, Victoria N Yi, Katja Remlinger, Ryan C. Fields, Roopa Srinivasan, Amaya I. Wolf, David J. Figueroa, Scott B. Berger, Michael L Washburn, William G. Hawkins, Julie G. Grossman, Stephanie Van Horn, Richard S. Hotchkiss, Heather Madsen, Andrew H. Walton, S. Peter Goedegebuure
Publikováno v:
J Immunol
Sepsis is characterized as life-threatening organ dysfunction caused by a dysregulated host immune response to infection. The purpose of this investigation was to determine the differential effect of sepsis on innate versus adaptive immunity, in huma
Autor:
Radhika Goenka, Fabien Dépis, Julie B. Engiles, Christophe Benoist, Michael P. Cancro, Daniel P. Beiting, Dorothy Cimino Brown, Christoph Konradt, Christopher A. Hunter, Sunglim Cho, Li-Fan Lu, James B. Wing, Jonathan S. Silver, Daniela Gómez Atria, Jan Erikson, Shimon Sakaguchi, William J. Quinn, Arielle Glatman Zaretsky, David Allman, Amaya I. Wolf
Publikováno v:
Cell Reports, Vol 18, Iss 8, Pp 1906-1916 (2017)
Long-lived plasma cells (PCs) in the bone marrow (BM) are a critical source of antibodies after infection or vaccination, but questions remain about the factors that control PCs. We found that systemic infection alters the BM, greatly reducing PCs an
Autor:
Richard G. Carroll, Martha Triantafilou, Evanna L. Mills, Amaya I. Wolf, Kathy Triantafilou, Clare E. Bryant, Silvia Galván-Peña, Robin Olden, Seth L. Masters, Meghana N. Patel
Publikováno v:
Trends in Molecular Medicine. 23:165-180
The inflammasome is a cytoplasmic protein complex that processes interleukins (IL)-1β and IL-18, and drives a form of cell death known as pyroptosis. Oligomerization of this complex is actually the second step of activation, and a priming step must
Autor:
Joshi M. Ramanjulu, G. Scott Pesiridis, Jingsong Yang, Nestor Concha, Robert Singhaus, Shu-Yun Zhang, Jean-Luc Tran, Patrick Moore, Stephanie Lehmann, H. Christian Eberl, Marcel Muelbaier, Jessica L. Schneck, Jim Clemens, Michael Adam, John Mehlmann, Joseph Romano, Angel Morales, James Kang, Lara Leister, Todd L. Graybill, Adam K. Charnley, Guosen Ye, Neysa Nevins, Kamelia Behnia, Amaya I. Wolf, Viera Kasparcova, Kelvin Nurse, Liping Wang, Ana C. Puhl, Yue Li, Michael Klein, Christopher B. Hopson, Jeffrey Guss, Marcus Bantscheff, Giovanna Bergamini, Michael A. Reilly, Yiqian Lian, Kevin J. Duffy, Jerry Adams, Kevin P. Foley, Peter J. Gough, Robert W. Marquis, James Smothers, Axel Hoos, John Bertin
Publikováno v:
Nature. 564(7736)
Stimulator of interferon genes (STING) is a receptor in the endoplasmic reticulum that propagates innate immune sensing of cytosolic pathogen-derived and self DNA1. The development of compounds that modulate STING has recently been the focus of inten
Autor:
David Artis, Krystyna Mozdzanowska, Jeffrey N. Weiser, Qin Liu, Maura C. Strauman, Jan Erikson, Amaya I. Wolf, Hao Shen, Scott E. Hensley, Katie L. Williams, Lisa C. Osborne, David S. Garlick, Andrew J. Caton
Publikováno v:
Virology. :254-265
The response to influenza virus (IAV) infection and severity of disease is highly variable in humans. We hypothesized that one factor contributing to this variability is the presence of specific respiratory tract (RT) microbes. One such microbe is St
Autor:
Ping Jiang, Hui Hu, Jeroen M. J. Tas, Gabriel D. Victora, Li-Yuan Chang, Enguang Bi, Timothy J Day, Lifeng Tian, Emily Becker, Changchun Xiao, Haikun Wang, Jan Erikson, Xinxin Wang, Jianlin Geng, Shane Crotty, Youn Soo Choi, Andrew V. Kossenkov, Hiroshi Takata, Amaya I. Wolf, Haley O. Tucker, Xiaomin Wen, Stephanie L. Sprout, Louise C. Showe, Jessica Willen
Publikováno v:
Nature Immunology. 15:667-675
CD4(+) follicular helper T cells (T(FH) cells) are essential for germinal center (GC) responses and long-lived antibody responses. Here we report that naive CD4(+) T cells deficient in the transcription factor Foxp1 'preferentially' differentiated in