Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Amaury Guillou"'
Autor:
Daniel F. Earley, Amaury Guillou, Simon Klingler, Rachael Fay, Melanie Gut, Faustine d’Orchymont, Shamisa Behmaneshfar, Linus Reichert, Jason P. Holland
Publikováno v:
JACS Au, Vol 2, Iss 3, Pp 646-664 (2022)
Externí odkaz:
https://doaj.org/article/33351dd3157747ecaf4e4c64f6038143
Autor:
Jennifer Lamb, Faustine d'Orchymont, Rachael Fay, Florian Gribi, Jose Esteban Flores, Melanie Gut, Simon Klingler, Patricia Pires, Jan Bühler, Shamisa Behmaneshfar, Amaury Guillou, Daniel F. Earley, Jason P. Holland
Publikováno v:
CHIMIA, Vol 74, Iss 12, Pp 946-952 (2020)
The synthesis, characterisation and application of radiolabelled compounds for use in diagnostic and therapeutic medicine requires a diverse skill set. This article highlights a selection of our ongoing projects that aim to provide new synthetic meth
Externí odkaz:
https://doaj.org/article/5d95a102eb33480c8a8fd891fd2c6f10
Publikováno v:
Molecules, Vol 26, Iss 3, p 764 (2021)
89Zr-radiolabelled proteins functionalised with desferrioxamine B are a cornerstone of diagnostic positron emission tomography. In the clinical setting, 89Zr-labelled proteins are produced manually. Here, we explore the potential of using a microflui
Externí odkaz:
https://doaj.org/article/bd6db6684f0f4b05a321a54d253406f8
Publikováno v:
Chemistry – A European Journal. 26:7185-7189
Protein‐conjugates are vital tools in biomedical research, drug discovery and imaging science. For example, functionalised monoclonal antibodies (mAbs) coupled to the desferrioxamine B (DFO) chelate and radiolabelled with 89Zr are used as radiophar
Publikováno v:
Inorganic chemistry frontiers. 9(12)
Herein, we report the synthesis of three new bifunctional heptadentate metal ion binding chelates derived from desferrioxamine B (DFO) linked to a tripeptide unit that comprises of a glutamic acid and two glycine residues. The three DFO derivatives w
Autor:
Axia Marlin, Ina Hierlmeier, Amaury Guillou, Mark Bartholomä, Raphaël Tripier, Véronique Patinec
Publikováno v:
Metallomics. 14
Three new bifunctional copper chelators based on the 1,4,7-triazacyclononane (tacn) platform have been synthesized and conjugated to peptides. The first one is constituted of the tacn with two methylpyridinyl and one methylthiazolyl carboxylic acid p
Autor:
Daniel F, Earley, Amaury, Guillou, Simon, Klingler, Rachael, Fay, Melanie, Gut, Faustine, d'Orchymont, Shamisa, Behmaneshfar, Linus, Reichert, Jason P, Holland
Publikováno v:
JACS Au. 2(3)
The creation of discrete, covalent bonds between a protein and a functional molecule like a drug, fluorophore, or radiolabeled complex is essential for making state-of-the-art tools that find applications in basic science and clinical medicine. Photo
Autor:
Henry VanBrocklin, Cyril Fong, Denis Beckford-Vera, Joseph Blecha, Amaury Guillou, Jason Holland, Timothy Henrich
Publikováno v:
Nuclear Medicine and Biology. :S52
Publikováno v:
Nuclear Medicine and Biology. :S119-S120
Autor:
Véronique Patinec, Luís M. P. Lima, Nicolas Le Poul, Amaury Guillou, Raphaël Tripier, David Esteban-Gómez, Carlos Platas-Iglesias, Rita Delgado, Mark Bartholomä
Publikováno v:
Inorganic Chemistry
Inorganic Chemistry, American Chemical Society, In press, ⟨10.1021/acs.inorgchem.8b03280⟩
Inorganic Chemistry, American Chemical Society, In press, ⟨10.1021/acs.inorgchem.8b03280⟩
International audience; We present here the synthesis of two new bifunctionalized azachelators, no2th-EtBzNCS and Hno2th1tha, as bioconjugable analogues of two previously described di- and trimethylthiazolyl 1,4,7-triazacyclononane (tacn) ligands, no