Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Amarylis C B A, Wanschel"'
Autor:
Coen van Solingen, Scott R. Oldebeken, Alessandro G. Salerno, Amarylis C. B. A. Wanschel, Kathryn J. Moore
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 8 (2021)
Investigations into the regulatory mechanisms controlling cholesterol homeostasis have proven fruitful in identifying low-density lipoprotein (LDL)-lowering therapies to reduce the risk of atherosclerotic cardiovascular disease. A major advance was t
Externí odkaz:
https://doaj.org/article/d7a3d43ee4e840f0bee2edb841757972
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 8 (2021)
Externí odkaz:
https://doaj.org/article/94e05bb43c8141e8afc5c2014beb6c5f
Autor:
Thiago Rentz, Amarylis C. B. A. Wanschel, Leonardo de Carvalho Moi, Estela Lorza-Gil, Jane C. de Souza, Renata R. dos Santos, Helena C. F. Oliveira
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
An early event in atherogenesis is the recruitment and infiltration of circulating monocytes and macrophage activation in the subendothelial space. Atherosclerosis subsequently progresses as a unresolved inflammatory disease, particularly in hypercho
Externí odkaz:
https://doaj.org/article/d2946ae866844d6abd0f5a91b3eff3dd
Autor:
Alessandro G. Salerno, Coen van Solingen, Elena Scotti, Amarylis C. B. A. Wanschel, Milessa S. Afonso, Scott R. Oldebeken, Westley Spiro, Peter Tontonoz, Katey J. Rayner, Kathryn J. Moore
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 7 (2020)
MicroRNAs (miRNA) have emerged as important post-transcriptional regulators of metabolic pathways that contribute to cellular and systemic lipoprotein homeostasis. Here, we identify two conserved miRNAs, miR-224, and miR-520d, which target gene netwo
Externí odkaz:
https://doaj.org/article/dd888e03050d4c62a7d61d2593abde3f
Autor:
Raul A Dulce, Rosemeire M Kanashiro-Takeuchi, Lauro M Takeuchi, Alessandro G Salerno, Amarylis C B A Wanschel, Shathiyah Kulandavelu, Wayne Balkan, Marilia S S R Zuttion, Renzhi Cai, Andrew V Schally, Joshua M Hare
Publikováno v:
Cardiovascular Research. 118:3586-3601
Aims To test the hypothesis that the activation of the growth hormone-releasing hormone (GHRH) receptor signalling pathway within the myocardium both prevents and reverses diastolic dysfunction and pathophysiologic features consistent with heart fail
Autor:
Amarylis C. B. A. Wanschel, Daniele M. Guizoni, Estela Lorza-Gil, Alessandro G. Salerno, Adriene A. Paiva, Gabriel G. Dorighello, Ana Paula Davel, Wayne Balkan, Joshua M. Hare, Helena C. F. Oliveira
Publikováno v:
Biomolecules, Vol 11, Iss 1, p 69 (2021)
Endothelial dysfunction precedes atherosclerosis and is an independent predictor of cardiovascular events. Cholesterol levels and oxidative stress are key contributors to endothelial damage, whereas high levels of plasma high-density lipoproteins (HD
Externí odkaz:
https://doaj.org/article/6e5b59f4fb194832873252fbe9e0250e
Autor:
Raul A, Dulce, Rosemeire M, Kanashiro-Takeuchi, Lauro M, Takeuchi, Alessandro G, Salerno, Amarylis C B A, Wanschel, Shathiyah, Kulandavelu, Wayne, Balkan, Marilia S S R, Zuttion, Renzhi, Cai, Andrew V, Schally, Joshua M, Hare
Publikováno v:
Cardiovasc Res
To test the hypothesis that the activation of the growth hormone-releasing hormone (GHRH) receptor signaling pathway within the myocardium both prevents and reverses diastolic dysfunction and pathophysiologic features consistent with heart failure wi
Autor:
Rosemeire M. Kanashiro-Takeuchi, Alessandro Salerno, Andrew V. Schally, Amarylis C. B. A. Wanschel, Peter Buchwald, Joshua M. Hare, Ivonne Hernandez Schulman, Raul A Dulce, Victoria Florea, Marcos Rosado, Darren Turner, Luiza Bagno, Wayne Balkan, Angela C. Rieger, Jose Rodriguez, Lauro M Takeuchi
Publikováno v:
Proc Natl Acad Sci U S A
Therapies for heart failure with preserved ejection fraction (HFpEF) are lacking. Growth hormone-releasing hormone agonists (GHRH-As) have salutary effects in ischemic and nonischemic heart failure animal models. Accordingly, we hypothesized that GHR
Autor:
Alessandro Salerno, Ana Paula Davel, Joshua M. Hare, Estela Lorza-Gil, Adriene Alexandra Paiva, Wayne Balkan, Amarylis C. B. A. Wanschel, Gabriel G. Dorighello, Helena C. F. Oliveira, Daniele M. Guizoni
Publikováno v:
Biomolecules
Volume 11
Issue 1
Biomolecules, Vol 11, Iss 69, p 69 (2021)
Volume 11
Issue 1
Biomolecules, Vol 11, Iss 69, p 69 (2021)
Endothelial dysfunction precedes atherosclerosis and is an independent predictor of cardiovascular events. Cholesterol levels and oxidative stress are key contributors to endothelial damage, whereas high levels of plasma high-density lipoproteins (HD
Autor:
Amarylis C. B. A. Wanschel, Raul A Dulce, Alessandro Salerno, Wayne Balkan, Joshua M. Hare, Konstantinos E. Hatzistergos
Publikováno v:
J Cardiovasc Aging
INTRODUCTION: Induced pluripotent stem cells (iPSCs) provide a model of cardiomyocyte (CM) maturation. Nitric oxide signaling promotes CM differentiation and maturation, although the mechanisms remain controversial. AIM: The study tested the hypothes