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pro vyhledávání: '"Amarshi Mukherjee"'
Autor:
Amarshi Mukherjee, Vanessa Jantsch, Rida Khan, Wolfgang Hartung, René Fischer, Jonathan Jantsch, Boris Ehrenstein, Maximilian F. Konig, Felipe Andrade
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Background:Aggregatibacter actinomycetemcomitans (Aa) is a Gram-negative coccobacillus recognized as a pathogen in periodontitis and infective endocarditis. By producing a toxin (leukotoxin A, LtxA) that triggers global hypercitrullination in neutrop
Externí odkaz:
https://doaj.org/article/35247255dbb54785b42ad585a1d925a3
Publikováno v:
Biochemistry and Biophysics Reports
Vibrio cholerae cytolysin/hemolysin (VCC) is a 65 kDa β-pore-forming toxin causing lysis and death of eukaryotic cells. Apart from the core cytolysin domain, VCC has two lectin domains with β-trefoil and β-prism folds. The β-prism domain binds to
Publikováno v:
Journal of Clinical Medicine
Journal of Clinical Medicine, Vol 8, Iss 9, p 1309 (2019)
Journal of Clinical Medicine, Vol 8, Iss 9, p 1309 (2019)
Rheumatoid arthritis (RA) is an autoimmune disease of unknown etiology characterized by immune-mediated damage of synovial joints and antibodies to citrullinated antigens. Periodontal disease, a bacterial-induced inflammatory disease of the periodont
Autor:
Maximilian F. Konig, Boris Ehrenstein, René Fischer, Vanessa Jantsch, Felipe Andrade, Rida Khan, Jonathan Jantsch, Wolfgang Hartung, Amarshi Mukherjee
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, Vol 9 (2018)
Frontiers in Immunology, Vol 9 (2018)
Background: Aggregatibacter actinomycetemcomitans (Aa) is a Gram-negative coccobacillus recognized as a pathogen in periodontitis and infective endocarditis. By producing a toxin (leukotoxin A, LtxA) that triggers global hypercitrullination in neutro
Publikováno v:
The Journal of biological chemistry. 289(7)
Vibrio cholerae cytolysin/hemolysin (VCC) is an amphipathic 65-kDa β-pore-forming toxin with a C-terminal β-prism lectin domain. Because deletion or point mutation of the lectin domain seriously compromises hemolytic activity, it is thought that ca