Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Amareeta K. Besra"'
Autor:
Liam R. Cox, Amareeta K. Besra, Himanshu Kharkwal, Natacha Veerapen, Gurdyal S. Besra, Alan Howell, Christopher T. Johndrow, Lianjun Zhang, Noemi Alejandra Saavedra-Avila, Peter J. Jervis, Leandro J. Carreño, Elizabeth E. Evans, Steven A. Porcelli, Samantha Rothberg, Alena Donda, Steven C. Almo, Maurice Zauderer, Shalu Sharma Kharkwal, Scott J. Garforth, Jinghang Zhang
Publikováno v:
Cancer Res
CD1d-restricted invariant natural killer T cells (iNKT cells) mediate strong antitumor immunity when stimulated by glycolipid agonists. However, attempts to develop effective iNKT cell agonists for clinical applications have been thwarted by potentia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c9e51cc5ecf1296bf2eb078435815ad
https://europepmc.org/articles/PMC8137529/
https://europepmc.org/articles/PMC8137529/
Publikováno v:
Molecular immunology. 129
Mucosal-associated invariant T cells (MAIT cells) represent a potential therapeutic target as they can tune or enhance immune responses. They recognise and become activated by antigens, presented by the monomorphic MHC-I related molecule, MR1. To ass
Autor:
Himanshu Kharkwal, Steven A. Porcelli, Judith V. Hobrath, Anne Dell, Patrick J. Moynihan, Peter J. Jervis, Gurdyal S. Besra, Liam R. Cox, Amareeta K. Besra, Simon J. North, Veemal Bhowruth, Stuart M. Haslam, Natacha Veerapen, Shalu Sharma Kharkwal, Maurice Zauderer, Padraic J. Quaid
Publikováno v:
Bioconjugate Chemistry. 29:3161-3173
Activation of invariant natural killer T lymphocytes (iNKT cells) by α-galactosylceramide (α-GC) elicits a range of pro-inflammatory or anti-inflammatory immune responses. We report the synthesis and characterization of a series of α-GC analogues