Development of the Sm14/GLA-SE Schistosomiasis Vaccine Candidate: An Open, Non-Placebo-Controlled, Standardized-Dose Immunization Phase Ib Clinical Trial Targeting Healthy Young Women.

Autor: Santini-Oliveira M; Evandro Chagas National Institute of Infectology, Fiocruz, Rio de Janeiro 21040-360, Brazil., Machado Pinto P; Laboratory of Experimental Schistosomiasis, Oswaldo Cruz Institute, Fiocruz, Rio de Janeiro 21045-900, Brazil., Santos TD; Laboratory of Experimental Schistosomiasis, Oswaldo Cruz Institute, Fiocruz, Rio de Janeiro 21045-900, Brazil., Vilar MM; Laboratory of Experimental Schistosomiasis, Oswaldo Cruz Institute, Fiocruz, Rio de Janeiro 21045-900, Brazil., Grinsztejn B; Evandro Chagas National Institute of Infectology, Fiocruz, Rio de Janeiro 21040-360, Brazil., Veloso V; Evandro Chagas National Institute of Infectology, Fiocruz, Rio de Janeiro 21040-360, Brazil., Paes-de-Almeida EC; Department of Basic Sciences, Fluminense Federal University, Nova Friburgo 28625-650, Brazil., Amaral MAZ; Program for Development of the Mata Atlântica Campus, Fiocruz, Rio de Janeiro 21045-900, Brazil., Ramos CR; Fenix Biotec Treinamento SS LTDA, São Paulo 05591-090, Brazil., Marroquin-Quelopana M; Fenix Biotec Treinamento SS LTDA, São Paulo 05591-090, Brazil., Coler R; Department of Global Health, University of Washington, Seattle, WA 98195, USA., Reed S; HDT Bio, Seattle, WA 98102, USA., Ciol MA; Department of Rehabilitation Medicine, School of Medicine, University of Washington, Seattle, WA 98105, USA., Savino W; Laboratory on Thymus Research, Oswaldo Cruz Institute, Fiocruz, Rio de Janeiro 21040-360, Brazil.; Brazilian National Institute of Science and Technology on Neuroimmunomodulation, Oswaldo Cruz Institute, Fiocruz, Rio de Janeiro 21040-360, Brazil., Parra JC; René Rachou Institute-Fiocruz/Minas, Fiocruz, Belo Horizonte 30190-002, Brazil., Almeida MSDS; Laboratory of Experimental Schistosomiasis, Oswaldo Cruz Institute, Fiocruz, Rio de Janeiro 21045-900, Brazil., Tendler M; Laboratory of Experimental Schistosomiasis, Oswaldo Cruz Institute, Fiocruz, Rio de Janeiro 21045-900, Brazil.

Publikováno v: Vaccines [Vaccines (Basel)] 2022 Oct 15; Vol. 10 (10). Date of Electronic Publication: 2022 Oct 15.