Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Amarachi V. Oleru"'
Autor:
Krishan K. Pandey, Sibes Bera, Ke Shi, Michael J. Rau, Amarachi V. Oleru, James A. J. Fitzpatrick, Alan N. Engelman, Hideki Aihara, Duane P. Grandgenett
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-10 (2021)
Pandey, Bera, Shi et al. report the cryo-electron microscopy structure of the Rous sarcoma virus octameric intasome complex stabilized by a HIV-1 integrase strand transfer inhibitor. This new structure highlights the intrinsic flexibility of the dist
Externí odkaz:
https://doaj.org/article/4d6bb66107444b65b39f3f0bed53819a
Autor:
Wen Li, Parmit K. Singh, Gregory A. Sowd, Gregory J. Bedwell, Sooin Jang, Vasudevan Achuthan, Amarachi V. Oleru, Doris Wong, Hind J. Fadel, KyeongEun Lee, Vineet N. KewalRamani, Eric M. Poeschla, Alon Herschhorn, Alan N. Engelman
Publikováno v:
mBio, Vol 11, Iss 5 (2020)
ABSTRACT Lentiviral DNA integration favors transcriptionally active chromatin. We previously showed that the interaction of human immunodeficiency virus type 1 (HIV-1) capsid with cleavage and polyadenylation specificity factor 6 (CPSF6) localizes vi
Externí odkaz:
https://doaj.org/article/7f4eaeb2c24147479988497d78e83da7
Autor:
Sibes Bera, Ke Shi, Amarachi V. Oleru, James A. J. Fitzpatrick, Michael J. Rau, Hideki Aihara, Duane P. Grandgenett, Krishan K. Pandey, Alan Engelman
Publikováno v:
Communications Biology
Communications Biology, Vol 4, Iss 1, Pp 1-10 (2021)
Communications Biology, Vol 4, Iss 1, Pp 1-10 (2021)
Despite conserved catalytic integration mechanisms, retroviral intasomes composed of integrase (IN) and viral DNA possess diverse structures with variable numbers of IN subunits. To investigate intasome assembly mechanisms, we employed the Rous sarco