Zobrazeno 1 - 10
of 63
pro vyhledávání: '"Amar Sahay"'
Publikováno v:
eLife, Vol 11 (2022)
Memories encoded in the dentate gyrus (DG) ‒ CA3 circuit of the hippocampus are routed from CA1 to anterior cingulate cortex (ACC) for consolidation. Although CA1 parvalbumin inhibitory neurons (PV INs) orchestrate hippocampal-cortical communicatio
Externí odkaz:
https://doaj.org/article/9b0367d36053449cb4b981b2dbca829f
Autor:
Nannan Guo, Kelsey D McDermott, Yu-Tzu Shih, Haley Zanga, Debolina Ghosh, Charlotte Herber, William R Meara, James Coleman, Alexia Zagouras, Lai Ping Wong, Ruslan Sadreyev, J Tiago Gonçalves, Amar Sahay
Publikováno v:
eLife, Vol 11 (2022)
Experience governs neurogenesis from radial-glial neural stem cells (RGLs) in the adult hippocampus to support memory. Transcription factors (TFs) in RGLs integrate physiological signals to dictate self-renewal division mode. Whereas asymmetric RGL d
Externí odkaz:
https://doaj.org/article/0e24b10980c34ec5a18e2dfb551081df
Publikováno v:
Cell Reports, Vol 30, Iss 7, Pp 2360-2373.e5 (2020)
Summary: Considerable work emphasizes a role for hippocampal circuits in governing contextual fear discrimination. However, the intra- and extrahippocampal pathways that route contextual information to cortical and subcortical circuits to guide adapt
Externí odkaz:
https://doaj.org/article/2ff836b4e25d4bfd8d7a1e3da662825e
Autor:
Antoine Besnard, Tomer Langberg, Sally Levinson, Duong Chu, Cinzia Vicidomini, Kimberly N. Scobie, Andrew J. Dwork, Victoria Arango, Gorazd B. Rosoklija, J. John Mann, René Hen, E. David Leonardo, Maura Boldrini, Amar Sahay
Publikováno v:
Cell Reports, Vol 23, Iss 11, Pp 3183-3196 (2018)
Summary: Stress exposure is associated with the pathogenesis of psychiatric disorders, including post-traumatic stress disorder (PTSD) and major depressive disorder (MDD). Here, we show in rodents that chronic stress exposure rapidly and transiently
Externí odkaz:
https://doaj.org/article/3c57edd6b6b14a11979a871628b1efed
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
While oxytocin is known to be critical for social recognition, the functions of oxytocin receptors (Oxtrs) in the hippocampus are not known. This study shows that Oxtrs in anterior dentate gyrus and CA2/CA3 pyramidal cells recruit population-based co
Externí odkaz:
https://doaj.org/article/ebf2b63d30ed4f07927a547ba3ada6f2
Autor:
Shai Kaluski, Miguel Portillo, Antoine Besnard, Daniel Stein, Monica Einav, Lei Zhong, Uwe Ueberham, Thomas Arendt, Raul Mostoslavsky, Amar Sahay, Debra Toiber
Publikováno v:
Cell Reports, Vol 18, Iss 13, Pp 3052-3062 (2017)
The histone deacetylase SIRT6 promotes DNA repair, but its activity declines with age with a concomitant accumulation of DNA damage. Furthermore, SIRT6 knockout mice exhibit an accelerated aging phenotype and die prematurely. Here, we report that bra
Externí odkaz:
https://doaj.org/article/2d6330c2933042aeba10c132fa2db6f9
Author Correction: Hippocampal oxytocin receptors are necessary for discrimination of social stimuli
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-1 (2018)
The original version of this Article contained an error in the spelling of the author Alexa H. Veenema, which was incorrectly given as Alexa Veenema. This has now been corrected in both the PDF and HTML versions of the Article.
Externí odkaz:
https://doaj.org/article/9ffa1a457473407e8e68da021e0b836d
Autor:
Travis Goode, Delara Chizari, Nina Sachdev, Antoine Besnard, Michael Kritzer, Devesh Pathak, Evan Macosko, Amar Sahay
Publikováno v:
Biological Psychiatry. 93:S151
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0b0810376f41d0577740f99bbeef3c4c
https://doi.org/10.1016/j.biopsych.2023.02.381
https://doi.org/10.1016/j.biopsych.2023.02.381
Publikováno v:
Neuron
The hippocampus and its extended network contribute to encoding and recall of episodic experiences. Drawing from recent anatomical, physiological, and behavioral studies, we propose that hippocampal engrams function as indices to mediate memory recal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ced48528b904fa57d5ea862b0a6ddf4b
http://id.nii.ac.jp/1394/00001546/
http://id.nii.ac.jp/1394/00001546/