Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Amar Koleti"'
Autor:
Marcin Pilarczyk, Mehdi Fazel-Najafabadi, Michal Kouril, Behrouz Shamsaei, Juozas Vasiliauskas, Wen Niu, Naim Mahi, Lixia Zhang, Nicholas A. Clark, Yan Ren, Shana White, Rashid Karim, Huan Xu, Jacek Biesiada, Mark F. Bennett, Sarah E. Davidson, John F. Reichard, Kurt Roberts, Vasileios Stathias, Amar Koleti, Dusica Vidovic, Daniel J. B. Clarke, Stephan C. Schürer, Avi Ma’ayan, Jarek Meller, Mario Medvedovic
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
There are only a few platforms that integrate multiple omics data types, bioinformatics tools, and interfaces for integrative analyses and visualization that do not require programming skills. Here the authors present an integrative web-based platfor
Externí odkaz:
https://doaj.org/article/08ffc15267ee4c3faac75343be39e39f
Autor:
Yu Lin, Saurabh Mehta, Hande Küçük-McGinty, John Paul Turner, Dusica Vidovic, Michele Forlin, Amar Koleti, Dac-Trung Nguyen, Lars Juhl Jensen, Rajarshi Guha, Stephen L. Mathias, Oleg Ursu, Vasileios Stathias, Jianbin Duan, Nooshin Nabizadeh, Caty Chung, Christopher Mader, Ubbo Visser, Jeremy J. Yang, Cristian G. Bologa, Tudor I. Oprea, Stephan C. Schürer
Publikováno v:
Journal of Biomedical Semantics, Vol 8, Iss 1, Pp 1-16 (2017)
Abstract Background One of the most successful approaches to develop new small molecule therapeutics has been to start from a validated druggable protein target. However, only a small subset of potentially druggable targets has attracted significant
Externí odkaz:
https://doaj.org/article/c7f21332499a4a20a9198a03f5457353
Autor:
Raymond Terryn, Alexander Lachmann, Vasileios Stathias, John Paul Turner, Afoma C. Umeano, Daniel J.B. Clarke, Dusica Vidovic, John Erol Evangelista, Amar Koleti, Marcin Pilarczyk, Stephan C. Schürer, Mehdi Fazel-Najafabadi, Caty Chung, Daniel J. Cooper, Avi Ma'ayan, Mario Medvedovic
Publikováno v:
Nucleic Acids Research
The Library of Integrated Network-Based Cellular Signatures (LINCS) is an NIH Common Fund program with the goal of generating a large-scale and comprehensive catalogue of perturbation-response signatures by utilizing a diverse collection of perturbat
Autor:
Giovanni Bocci, Noel Southall, Dusica Vidovic, Cristian Bologa, Lars Juhl Jensen, Stephan C. Schürer, Tudor I. Oprea, Jayme Holmes, Vishal B. Siramshetty, Amar Koleti, Poorva Dharkar, Dac-Trung Nguyen, Anna Waller, Jeremy J. Yang, Timothy Sheils, Keith J. Kelleher, Anton Simeonov, Stephen L. Mathias, Ewy Mathé
Publikováno v:
Sheils, T K, Mathias, S L, Kelleher, K J, Siramshetty, V B, Nguyen, D T, Bologa, C G, Jensen, L J, Vidović, D, Koleti, A, Schürer, S C, Waller, A, Yang, J J, Holmes, J, Bocci, G, Southall, N, Dharkar, P, Mathé, E, Simeonov, A & Oprea, T I 2021, ' TCRD and Pharos 2021 : mining the human proteome for disease biology ', Nucleic Acids Research, vol. 49, no. D1, pp. D1334-D1346 . https://doi.org/10.1093/nar/gkaa993
Nucleic Acids Research
Nucleic Acids Research
In 2014, the National Institutes of Health (NIH) initiated the Illuminating the Druggable Genome (IDG) program to identify and improve our understanding of poorly characterized proteins that can potentially be modulated using small molecules or biolo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6b704a90589085c564c27e01092a99c
https://curis.ku.dk/ws/files/256214286/gkaa993_1.pdf
https://curis.ku.dk/ws/files/256214286/gkaa993_1.pdf
Autor:
Shana White, Marcin Pilarczyk, Lixia Zhang, Juozas Vasiliauskas, Sarah E. Davidson, Amar Koleti, Dusica Vidovic, Nicholas A. Clark, Stephan C. Schürer, Rashid Saadman Karim, Jacek Biesiada, Avi Ma'ayan, Daniel J.B. Clarke, John F. Reichard, Mark F. Bennett, Yan Ren, Vasileios Stathias, Behrouz Shamsaei, Naim Al Mahi, Jarek Meller, Mario Medvedovic, Wen Niu, Michal Kouril, Huan Xu, Kurt Roberts
There are only a few platforms that integrate multiple omics data types, bioinformatics tools, and interfaces for integrative analyses and visualization that do not require programming skills. Among these, iLINCS is unique in scope and versatility of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bfeea46ff70141c67a3f6ec14a71981
Autor:
Nicholas A. Clark, Marc R. Birtwistle, Jennifer E. Van Eyk, Moshe C. Silverstein, Caitlin E. Mills, Mario Niepel, Marcin Pilarczyk, Alexander Lachmann, Elizabeth H. Williams, Simon Koplev, Nathanael S. Gray, Uzma Hussain, Albert Lee, Ajay Pillai, Edward He, Mark A. Dane, Evren U. Azeloglu, Dusica Vidovic, Jeannette Osterloh, Maria G. Banuelos, Maxim V. Kuleshov, Rick J. Koch, Stephan C. Schürer, Karen Sachs, Damir Sudar, Divya Ramamoorthy, Dhruv Sareen, Shana White, Heidi S. Feiler, Siva Sivaganesan, Kathleen M. Jagodnik, Clive N. Svendsen, Mohammad Fallahi-Sichani, Miriam Adam, Jaroslaw Meller, Todd R. Golub, Ravi Iyengar, Jennifer Stocksdale, Amar Koleti, David Wrobel, Sherry L. Jenkins, Jacob D. Jaffe, Alexandra B Keenan, Renan Escalante-Chong, Daniel J. Cooper, Loren Ornelas, Joe W. Gray, Alexander LeNail, Ritchie Ho, Alyssa Coye, Avi Ma'ayan, Steve Finkbiener, Lixia Zhang, Andrea Matlock, Eric A. Sobie, Vidya Venkatraman, Anders B. Dohlman, Jeffrey D. Rothstein, Michele Forlin, Jonathan Z. Li, Rebecca Smith, Naim Al Mahi, Kaylyn Devlin, Caty Chung, Marc Hafner, Malvina Papanastasiou, Wen Niu, Michal Kouril, Ryan G. Lim, Yan Ren, Julia A. Kaye, Malcolm Casale, Jie Wu, Mario Medvedovic, Jeremy L. Muhlich, Victoria Dardov, Jouzas Vasiliauskas, Kelly Haston, Caroline E. Shamu, Raymond Terryn, John F. Reichard, Michel Nederlof, David Kilburn, Leslie M. Thompson, Jia-Ren Lin, Vasileios Stathias, Zichen Wang, Behrouz Shamsaei, James E. Korkola, Pamela Milani, Berhan Mandefro, Terri G. Thompson, Laura M. Heiser, Gavin Daigle, Denis Torre, Ron Margolis, Aravind Subramanian, Elmar Bucher, Sean D. Erickson, Ernest Fraenkel, Jaslin Kalra, Mark A. LaBarge, Gordon B. Mills, Peter K. Sorger, Sean M. Gross, Leslie Derr, Mehdi Fazel
Publikováno v:
Cell Systems. 6:13-24
The Library of Integrated Network-Based Cellular Signatures (LINCS) is an NIH Common Fund program that catalogs how human cells globally respond to chemical, genetic, and disease perturbations. Resources generated by LINCS include experimental and co
Autor:
Caty Chung, Nicholas A. Clark, Michele Forlin, John Paul Turner, Christopher C. Mader, Mehdi Fazel, Sherry L. Jenkins, Amar Koleti, Naim Al Mahi, John F. Reichard, Tanya T. Kelley, Alessandro D'Urso, Kathleen M. Jagodnik, Dusica Vidovic, Mario Medvedovic, Marcin Pilarczyk, Vasileios Stathias, Behrouz Shamsaei, Lily Wang, Wen Niu, Avi Ma'ayan, Stephan C. Schürer, Daniel J. Cooper, Denis Torre, Bryce K. Allen, Raymond Terryn, Juozas Vasiliauskas, Jarek Meller, Ajay Pillai
Publikováno v:
Nucleic Acids Research
The Library of Integrated Network-based Cellular Signatures (LINCS) program is a national consortium funded by the NIH to generate a diverse and extensive reference library of cell-based perturbation-response signatures, along with novel data analyti
Autor:
Dusica Vidovic, Cristian Bologa, Christopher Mader, Jeremy J. Yang, Stephan C. Schürer, Tudor I. Oprea, Vasileios Stathias, Lars Juhl Jensen, Stephen L. Mathias, Yu Lin, Hande Küçük-McGinty, Nooshin Nabizadeh, Saurabh Mehta, Oleg Ursu, Rajarshi Guha, Michele Forlin, Dac-Trung Nguyen, Ubbo Visser, Jianbin Duan, Amar Koleti, John Paul Turner, Caty Chung
Publikováno v:
Lin, Y, Mehta, S, Küçük-McGinty, H, Turner, J P, Vidovic, D, Forlin, M, Koleti, A, Nguyen, D-T, Jensen, L J, Guha, R, Mathias, S L, Ursu, O, Stathias, V, Duan, J, Nabizadeh, N, Chung, C, Mader, C, Visser, U, Yang, J J, Bologa, C G, Oprea, T I & Schürer, S C 2017, ' Drug target ontology to classify and integrate drug discovery data ', Journal of Biomedical Semantics, vol. 8, no. 1, 50 . https://doi.org/10.1186/s13326-017-0161-x
Journal of Biomedical Semantics
Journal of Biomedical Semantics, Vol 8, Iss 1, Pp 1-16 (2017)
Journal of Biomedical Semantics
Journal of Biomedical Semantics, Vol 8, Iss 1, Pp 1-16 (2017)
BackgroundOne of the most successful approaches to develop new small molecule therapeutics has been to start from a validated druggable protein target. However, only a small subset of potentially druggable targets has attracted significant research a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a607e862d3e37df637108b26ea053b73
https://curis.ku.dk/portal/da/publications/drug-target-ontology-to-classify-and-integrate-drug-discovery-data(c8da5b40-158d-4821-9130-1662a4ef2cb7).html
https://curis.ku.dk/portal/da/publications/drug-target-ontology-to-classify-and-integrate-drug-discovery-data(c8da5b40-158d-4821-9130-1662a4ef2cb7).html
Autor:
Raymond Terryn, Dusica Vidovic, Caty Chung, Denis Torre, Kathleen M. Jagodnik, Mario Medvedovic, Vasileios Stathias, Nagi G. Ayad, Ajay Pillai, Amar Koleti, Michele Forlin, Daniel J. Cooper, Avi Ma'ayan, Stephan C. Schürer
Publikováno v:
Scientific Data
The NIH-funded LINCS Consortium is creating an extensive reference library of cell-based perturbation response signatures and sophisticated informatics tools incorporating a large number of perturbagens, model systems, and assays. To date, more than
Publikováno v:
Frontiers in Genetics, Vol 5 (2014)
Frontiers in Genetics
Frontiers in Genetics
The Library of Integrated Network-based Cellular Signatures (LINCS) project is a large-scale coordinated effort to build a comprehensive systems biology reference resource. The goals of the program include the generation of a very large multidimensio