Zobrazeno 1 - 10
of 524
pro vyhledávání: '"Amar, Gajjar"'
Autor:
Quynh T. Tran, Alex Breuer, Tong Lin, Ruth Tatevossian, Sariah J. Allen, Michael Clay, Larissa V. Furtado, Mark Chen, Dale Hedges, Tylman Michael, Giles Robinson, Paul Northcott, Amar Gajjar, Elizabeth Azzato, Sheila Shurtleff, David W. Ellison, Stanley Pounds, Brent A. Orr
Publikováno v:
npj Precision Oncology, Vol 8, Iss 1, Pp 1-12 (2024)
Abstract As part of the advancement in therapeutic decision-making for brain tumor patients at St. Jude Children’s Research Hospital (SJCRH), we developed three robust classifiers, a deep learning neural network (NN), k-nearest neighbor (kNN), and
Externí odkaz:
https://doaj.org/article/04b24c66871347abb0fb60d227703a96
Autor:
Rozalyn L. Rodwin, Fang Wang, Lu Lu, Zhenghong Li, Deo Kumar Srivastava, Nicholas S. Phillips, Raja B. Khan, Tara M. Brinkman, Kevin R. Krull, Frederick A. Boop, Gregory T. Armstrong, Thomas E. Merchant, Amar Gajjar, Leslie L. Robison, Melissa M. Hudson, Nina S. Kadan‐Lottick, Kirsten K. Ness
Publikováno v:
Cancer Medicine, Vol 13, Iss 14, Pp n/a-n/a (2024)
Abstract Background Survivors of childhood central nervous system (CNS) tumors can develop motor and sensory impairment from their cancer and treatment history. We estimated the prevalence of motor and sensory impairment in survivors compared with co
Externí odkaz:
https://doaj.org/article/278b0ae0302d475590d0b7d315855523
Autor:
Josue L. Dalboni da Rocha, Ping Zou Stinnett, Matthew A. Scoggins, Samuel S. McAfee, Heather M. Conklin, Amar Gajjar, Ranganatha Sitaram
Publikováno v:
Brain Sciences, Vol 14, Iss 9, p 904 (2024)
Medulloblastoma, a malignant brain tumor primarily affecting children, poses significant challenges to patients and clinicians due to its complex treatment and potential long-term cognitive consequences. While recent advancements in treatment have si
Externí odkaz:
https://doaj.org/article/7209534172dc44558e04c3d860d95c5d
Autor:
Supriya Sarvode, Amar Gajjar
Publikováno v:
Pediatric Hematology Oncology Journal, Vol 8, Iss 2, Pp 121-128 (2023)
Medulloblastoma (MB) is a brain tumor composed of distinct molecularly defined subgroups. Recent advances in genomics and transcriptomics have revealed >12 subtypes within the previously identified four subgroups. Molecular classification has improve
Externí odkaz:
https://doaj.org/article/1ad7096428154a66bdbb11acb6245809
Autor:
Daniel C. Moreira, Catherine G. Lam, Nickhill Bhakta, Frederick A. Boop, Jason Chiang, Thomas E. Merchant, Carlos Rodriguez-Galindo, Amar Gajjar, Ibrahim Qaddoumi
Publikováno v:
JCO Global Oncology, Vol , Iss 9 (2023)
Externí odkaz:
https://doaj.org/article/bcd581bc9ce94eabaae8929fd715afe9
Autor:
Chen He, Ke Xu, Xiaoyan Zhu, Paige S. Dunphy, Brian Gudenas, Wenwei Lin, Nathaniel Twarog, Laura D. Hover, Chang-Hyuk Kwon, Lawryn H. Kasper, Junyuan Zhang, Xiaoyu Li, James Dalton, Barbara Jonchere, Kimberly S. Mercer, Duane G. Currier, William Caufield, Yingzhe Wang, Jia Xie, Alberto Broniscer, Cynthia Wetmore, Santhosh A. Upadhyaya, Ibrahim Qaddoumi, Paul Klimo, Frederick Boop, Amar Gajjar, Jinghui Zhang, Brent A. Orr, Giles W. Robinson, Michelle Monje, Burgess B. Freeman III, Martine F. Roussel, Paul A. Northcott, Taosheng Chen, Zoran Rankovic, Gang Wu, Jason Chiang, Christopher L. Tinkle, Anang A. Shelat, Suzanne J. Baker
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
Patient-derived xenografts provide a resource for basic and translational cancer research. Here, the authors generate multiple pediatric high-grade glioma xenografts, use omics technologies to show that they are representative of primary tumours and
Externí odkaz:
https://doaj.org/article/879be8929790465bbe548678fef6db02
Autor:
Anthony P. Y. Liu, Qi Liu, Matthew M. K. Shing, Dennis T. L. Ku, Eric Fu, Chung-Wing Luk, Siu-Cheung Ling, Kevin K. F. Cheng, Dora L. W. Kwong, Wilson W. S. Ho, Ho-Keung Ng, Amar Gajjar, Yutaka Yasui, Godfrey C. F. Chan, Gregory T. Armstrong
Publikováno v:
JCO Global Oncology, Vol , Iss 6, Pp 704-721 (2020)
PURPOSE Despite being the most common pediatric solid tumors, incidence and outcome of CNS tumors in Chinese children have not been systematically reported. We addressed this knowledge gap by comparing the epidemiology of pediatric CNS tumors in Hong
Externí odkaz:
https://doaj.org/article/c005d0a9f6ca4072a98e35fc9a5f7ad6
Autor:
Jason Chiang, Alexander K. Diaz, Lydia Makepeace, Xiaoyu Li, Yuanyuan Han, Yimei Li, Paul Klimo, Frederick A. Boop, Suzanne J. Baker, Amar Gajjar, Thomas E. Merchant, David W. Ellison, Alberto Broniscer, Zoltan Patay, Christopher L. Tinkle
Publikováno v:
Acta Neuropathologica Communications, Vol 8, Iss 1, Pp 1-12 (2020)
Abstract Diffuse intrinsic pontine glioma (DIPG) is most commonly diagnosed based on imaging criteria, with biopsy often reserved for pontine tumors with imaging features not typical for DIPG (atypical DIPG, ‘aDIPG’). The histopathologic and mole
Externí odkaz:
https://doaj.org/article/2975b5b4fe224850879f46dfd3e6eae4
Autor:
Anthony P. Y. Liu, Julie H. Harreld, Lisa M. Jacola, Madelyn Gero, Sahaja Acharya, Yahya Ghazwani, Shengjie Wu, Xiaoyu Li, Paul Klimo, Amar Gajjar, Jason Chiang, Ibrahim Qaddoumi
Publikováno v:
Acta Neuropathologica Communications, Vol 6, Iss 1, Pp 1-12 (2018)
Abstract Tectal glioma (TG) is a rare low-grade tumor occurring predominantly in the pediatric population. There has been no detailed analysis of molecular alterations in TG. Risk factors associated with inferior outcome and long-term sequelae of TG
Externí odkaz:
https://doaj.org/article/3b3750daf3cc4b09b688c4851ce19f1c
Autor:
Anthony P. Y. Liu, Sandeep K. Dhanda, Tong Lin, Edgar Sioson, Aksana Vasilyeva, Brian Gudenas, Ruth G. Tatevossian, Sujuan Jia, Geoffrey Neale, Daniel C. Bowers, Tim Hassall, Sonia Partap, John R. Crawford, Murali Chintagumpala, Eric Bouffet, Geoff McCowage, Alberto Broniscer, Ibrahim Qaddoumi, Greg Armstrong, Karen D. Wright, Santhosh A. Upadhyaya, Anna Vinitsky, Christopher L. Tinkle, John Lucas, Jason Chiang, Daniel J. Indelicato, Robert Sanders, Paul Klimo, Frederick A. Boop, Thomas E. Merchant, David W. Ellison, Paul A. Northcott, Brent A. Orr, Xin Zhou, Arzu Onar-Thomas, Amar Gajjar, Giles W. Robinson
Publikováno v:
Acta Neuropathologica. 144:733-746
Methylation profiling has radically transformed our understanding of tumors previously called central nervous system primitive neuro-ectodermal tumors (CNS-PNET). While this marks a momentous step toward defining key differences, reclassification has