Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Amanuiel Z. Taddese"'
Autor:
Magdalene K. Montgomery, Jacqueline Bayliss, Shuai Nie, William de Nardo, Stacey N. Keenan, Marziyeh Anari, Amanuiel Z. Taddese, Nicholas A. Williamson, Geraldine J. Ooi, Wendy A. Brown, Paul R. Burton, Paul Gregorevic, Craig A. Goodman, Kevin I. Watt, Matthew J. Watt
Publikováno v:
Diabetes. 72:715-727
Non-alcoholic fatty liver disease (NAFLD) and impaired glycaemic control are closely linked, however, the pathophysiological mechanisms underpinning this bidirectional relationship remain unresolved. The high secretory capacity of the liver and impai
Autor:
Jacqueline Bayliss, Magdalene K. Montgomery, Shuai Nie, Matthew J. Watt, Nicholas A. Williamson, Amanuiel Z. Taddese
Publikováno v:
The FASEB Journal. 35
Hexosaminidase A (HexA), a heterodimer consisting of HEXA and HEXB, converts the ganglioside sphingolipid GM2 to GM3 by removing a terminal N-acetyl-d-galactosamine. HexA enzyme deficiency in humans leads to GM2 accumulation in cells, particularly in