Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Amani Makkouk"'
Autor:
Kevin P Nishimoto, Taylor Barca, Aruna Azameera, Amani Makkouk, Jason M Romero, Lu Bai, Mary M Brodey, Jackie Kennedy‐Wilde, Hui Shao, Stephanie Papaioannou, Amy Doan, Cynthia Masri, Ngoc T Hoang, Hayden Tessman, Vidhya Dhevi Ramanathan, Ana Giner‐Rubio, Frank Delfino, Kriti Sharma, Kevin Bray, Matthew Hoopes, Daulet Satpayev, Ranjita Sengupta, Marissa Herrman, Stewart E Abbot, Blake T Aftab, Zili An, Swapna Panuganti, Sandra M Hayes
Publikováno v:
Clinical & Translational Immunology, Vol 11, Iss 2, Pp n/a-n/a (2022)
Abstract Objectives Autologous chimeric antigen receptor (CAR) αβ T‐cell therapies have demonstrated remarkable antitumor efficacy in patients with haematological malignancies; however, not all eligible cancer patients receive clinical benefit. E
Externí odkaz:
https://doaj.org/article/be2e5138abef45428e2a323fe55af735
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Obesity has reached global epidemic proportions and its effects on interactions between the immune system and malignancies, particularly as related to cancer immunotherapy outcomes, have come under increasing scrutiny. Although the vast majority of p
Externí odkaz:
https://doaj.org/article/a5b802dd287d4367877452108ac08ad1
Autor:
Peng Li, Amani Makkouk, Jennifer Gordetsky, Eddy Yang, Lewis Thomas, Lakshminarayanan Nandagopal, Hesham Yasin, Rohan Garje, Shannon K Boi, Rachael M Orlandella, Justin Tyler Gibson, William James Turbitt, Gal Wald, Claire Buchta Rosean, Katlyn E Norris, Megan Bing, Laura Bertrand, Brett P Gross, Dmytro Starenki, Kristine I Farag, Robert E Sorge, James A Brown, David M Lubaroff, Rebecca C Arend, Kenneth Nepple, Tatiana T Marquez-Lago, Lyse A Norian
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 2 (2020)
Background Obesity is a major risk factor for renal cancer, yet our understanding of its effects on antitumor immunity and immunotherapy outcomes remains incomplete. Deciphering these associations is critical, given the growing clinical use of immune
Externí odkaz:
https://doaj.org/article/e32b1f2582bd4a1abceb494628d92ae8
Autor:
Susanne M. Steggerda, Mark K. Bennett, Jason Chen, Ethan Emberley, Tony Huang, Julie R. Janes, Weiqun Li, Andrew L. MacKinnon, Amani Makkouk, Gisele Marguier, Peter J. Murray, Silinda Neou, Alison Pan, Francesco Parlati, Mirna L. M. Rodriguez, Lee-Ann Van de Velde, Tracy Wang, Melissa Works, Jing Zhang, Winter Zhang, Matthew I. Gross
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 5, Iss 1, Pp 1-18 (2017)
Abstract Background Myeloid cells are an abundant leukocyte in many types of tumors and contribute to immune evasion. Expression of the enzyme arginase 1 (Arg1) is a defining feature of immunosuppressive myeloid cells and leads to depletion of L-argi
Externí odkaz:
https://doaj.org/article/e6521eae41ac406fb6124cdd07cf5f4d
Autor:
Jim Li, Lijing Chen, Roland J. Billedeau, Timothy F. Stanton, John T. P. Chiang, Clarissa C. Lee, Weiqun Li, Susanne Steggerda, Ethan Emberley, Matthew Gross, Deepthi Bhupathi, Xiaoying Che, Jason Chen, Rosalyn Dang, Tony Huang, Yong Ma, Andrew MacKinnon, Amani Makkouk, Gisele Marguier, Silinda Neou, Natalija Sotirovska, Sandra Spurlock, Jing Zhang, Winter Zhang, Michael van Zandt, Lin Yuan, Jennifer Savoy, Francesco Parlati, Eric B. Sjogren
Publikováno v:
Journal of Medicinal Chemistry. 66:345-370
Autor:
George J. Weiner, Aliasger K. Salem, Sue E. Blackwell, Alicia K. Olivier, Amaraporn Wongrakpanich, Caitlin D. Lemke, Vijaya B. Joshi, Amani Makkouk
Figure S1. Synthesis and characterization of Dox MPs. Figure S2. Dox MPs enhance phagocytosis of A20 by DCs. Figure S3. Dox MPs exert similar effects to soluble Dox in human cell lines. Figure S4. All therapy components are required for maximum effic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e3841dc716ca8ac0d2cfba4539b1cc6
https://doi.org/10.1158/2326-6066.22537451.v1
https://doi.org/10.1158/2326-6066.22537451.v1
Autor:
George J. Weiner, Aliasger K. Salem, Sue E. Blackwell, Alicia K. Olivier, Amaraporn Wongrakpanich, Caitlin D. Lemke, Vijaya B. Joshi, Amani Makkouk
In situ immunization aims at generating antitumor immune responses through manipulating the tumor microenvironment. On the basis of recent advances in the understanding of antitumor immunity, we designed a three-step approach to in situ immunization
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bdfc505931d2536c04cefcdcacb5026a
https://doi.org/10.1158/2326-6066.c.6548453.v1
https://doi.org/10.1158/2326-6066.c.6548453.v1
Autor:
Lyse A. Norian, Rohan Garje, Lewis Thomas, Shannon K. Boi, Rebecca C. Arend, Claire Buchta Rosean, Brett P. Gross, Lakshminarayanan Nandagopal, David M. Lubaroff, Rachael M. Orlandella, Kenneth G. Nepple, Dmytro Starenki, William J. Turbitt, George J. Weiner, Katlyn E Norris, Gal Wald, Kristine I Farag, Megan Bing, Eddy S. Yang, Jennifer B. Gordetsky, Robert E. Sorge, Amani Makkouk, Hesham A Yasin, James A. Brown, Peng Li, Justin T. Gibson, Tatiana T. Marquez-Lago, Yousef Zakharia, Laura A. Bertrand, Aliasger K. Salem
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 2 (2020)
Journal for Immunotherapy of Cancer
Journal for Immunotherapy of Cancer
BackgroundObesity is a major risk factor for renal cancer, yet our understanding of its effects on antitumor immunity and immunotherapy outcomes remains incomplete. Deciphering these associations is critical, given the growing clinical use of immune
Autor:
Amani Makkouk, Xue (Cher) Yang, Taylor Barca, Anthony Lucas, Mustafa Turkoz, Jonathan T S Wong, Kevin P Nishimoto, Mary M Brodey, Maryam Tabrizizad, Smitha R Y Gundurao, Lu Bai, Arun Bhat, Zili An, Stewart Abbot, Daulet Satpayev, Blake T Aftab, Marissa Herrman
Publikováno v:
Journal for Immunotherapy of Cancer
BackgroundGlypican-3 (GPC-3) is an oncofetal protein that is highly expressed in various solid tumors, but rarely expressed in healthy adult tissues and represents a rational target of particular relevance in hepatocellular carcinoma (HCC). Autologou
Autor:
Amani Makkouk, Daulet Satpayev, Taylor Barca, Jonathan Wong, Zili An, Anthony Lucas, Xue (Cher) Yang, Mustafa Turkoz, Maryam Tabrizizad, Marissa Herrman, Kevin Nishimoto, Mary Brody, Stewart Abbot, Smitha Gundurao, Lu Bai, Arun Bhat
Publikováno v:
Journal for ImmunoTherapy of Cancer. 9:A128-A128
BackgroundGlypican-3 (GPC-3) is an oncofetal protein that is highly expressed in various solid tumors including hepatocellular carcinoma (HCC) but is rarely expressed in healthy adult tissues and serves as a therapeutic target of interest. Autologous