Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Amani M.R. Alsaedi"'
Publikováno v:
Arabian Journal of Chemistry, Vol 15, Iss 5, Pp 103782- (2022)
The present article deals with the synthesis of novel nano-sized fluorinated thiazoles and studying their anticancer potentiality. The targeted azoles could be accessed via trifluoro-methylated thiosemicarbazone (3) prepared by reaction of with thios
Externí odkaz:
https://doaj.org/article/4a5232a9af09498694c83d98aecb4e51
Autor:
Sobhi M. Gomha, Thoraya A. Farghaly, Amani M.R. Alsaedi, Jihan Qurban, AbdElAziz A. Nayl, Yasser H. Zaki
Publikováno v:
Current Organic Chemistry. 26:1431-1452
Abstract: A literature survey revealed that a great deal of interest had been focused on the synthesis of functionalized heterocyclic compounds due to their wide range of biological activities such as antimicrobial, antitumor, anti-inflammatory, anti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::155a033dbe53a9077466b12966b96a4a
https://doi.org/10.2174/1385272827666221102145301
https://doi.org/10.2174/1385272827666221102145301
Autor:
Thoraya A. Farghaly, Hanan Gaber Abdulwahab, Hanadi Y. Medrasi, Mariam A. Al-sheikh, Dina F. Katowah, Amani M.R. Alsaedi
Publikováno v:
Bioorganic Chemistry. 128:106043
Novel tetracyclic pyrazolo[1,5-a]pyrimidine derivatives; namely benzo[3,4]cyclohepta[1,2-e]pyrazolo[1,5-a]pyrimidin-2-amines 6a-e and benzo[3,4]cyclohepta[1,2-e]pyrazolo[1,5-a]pyrimidin-2(6H)-ones 15a-d, were designed and synthesized as topoisomerase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04452c5d78c5601e7535e1d5b903c262
https://doi.org/10.1016/j.bioorg.2022.106043
https://doi.org/10.1016/j.bioorg.2022.106043
Autor:
Abrar Bayazeed, Noof A. Alenazi, Amani M.R. Alsaedi, Mona H. Ibrahim, Nadia T. Al-Qurashi, Thoraya A. Farghaly
Publikováno v:
Journal of Molecular Structure. 1258:132653
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::502a6b8d198604836486f24ef38d4679
https://doi.org/10.1016/j.molstruc.2022.132653
https://doi.org/10.1016/j.molstruc.2022.132653
Autor:
Khaled D. Khalil, Thoraya A. Farghaly, Marwa F. Harras, Samar J. Almehmadi, Amani M.R. Alsaedi
Publikováno v:
Journal of Molecular Structure. 1250:131832
The vascular endothelial growth factor receptor 2 (VEGFR2) is considered as a significant target for inhibition in the discovery of novel molecules with anti-proliferative activity. Here, we report the synthesis of novel derivatives of 1,2,4-triazole
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1a702f26ae7385fa3c50fc4c00d50595
https://doi.org/10.1016/j.molstruc.2021.131832
https://doi.org/10.1016/j.molstruc.2021.131832
Publikováno v:
Bioorganic Chemistry. 117:105431
Based on the structural study of previously known CDK2 inhibitors, a new series of pyrazolo[1,5-a]pyrimidine derivatives was designed and synthesized. The target compounds were biologically assessed as potent CDK2 inhibitors and promising anti-leukem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3254c2b47a7c53b86cc00d7a6a57c90
https://doi.org/10.1016/j.bioorg.2021.105431
https://doi.org/10.1016/j.bioorg.2021.105431