Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Amani, Sorour"'
Publikováno v:
American Journal of Molecular Biology. :49-72
Background: Circulating microRNAs are potential biomarkers of diagnostic and prognostic impact in various inflammatory and malignant diseases. Aim: Linking inflammation with malignancy, we studied miRNA-21 in sera of hepatitis-C-virus (HCV) and none
Autor:
Mohamed Eldafrawi, Zeinab I Mourad, Amani Sorour, Nabil A Elhalawani, Omar Ghallab, Nahla A M Hamed
Publikováno v:
American Journal of Molecular Biology. :1-10
Background: MicroRNAs (miRNAs) are short noncoding RNAs of ~21 to 23 nucleotides in length that post-transcriptionally regulate mRNA expression. Highthroughput methodologies have shown deregulated miRNA expression in an increasing number of human can
Publikováno v:
Genetic Testing and Molecular Biomarkers. 17:195-201
To investigate if there is an association between the different DNA repair gene polymorphisms and the risk of development of acute myeloid leukemia (AML) in a sample of the Egyptian population and to find out if there is any interaction between these
Publikováno v:
The Egyptian Journal of Haematology. 43:103
Background Numerous recurrent chromosomal aberrations have been identified in acute myeloid leukemia (AML), and their detection has become essential for accurate diagnosis, classification, and prognosis of the disease. Fluorescence in-situ hybridizat
Autor:
Paul Sinclair, M Martineau, Amani Sorour, Elena O’Neill, Wayne A. Mitchell, Letizia Foroni, Christine J. Harrison
Publikováno v:
Cancer Research. 64:4089-4098
With the objective of identifying candidate tumor suppressor genes, we used fluorescence in situ hybridization to map leukemia-related deletions of the long arm of chromosome 6 (6q). Twenty of 24 deletions overlapped to define a 4.8-Mb region of mini
Publikováno v:
Cancer Genetics and Cytogenetics. 121:128-132
Chromosome 8 abnormalities are seen in 80% of patients with T-cell prolymphocytic leukemia (T-PLL). The abnormalities described are idic(8)(p11),t(8;8)(p11;q12),+8, and 8p+ with the involvement of 8p. To localize 8p11–p12 breakpoints in T-PLL, meta
Autor:
Amani, Sorour, Dalia, Nafea
Publikováno v:
The Egyptian journal of immunology. 15(2)
In acute myeloid leukemia (AML), clonal chromosomal aberrations constitute markers of diagnostic value and the molecular characterization of numerous abnormalities has greatly improved the understanding of the biology of distinct subtypes of the dise
Autor:
Paul B, Sinclair, Amani, Sorour, Mary, Martineau, Christine J, Harrison, Wayne A, Mitchell, Elena, O'Neill, Letizia, Foroni
Publikováno v:
Cancer research. 64(12)
With the objective of identifying candidate tumor suppressor genes, we used fluorescence in situ hybridization to map leukemia-related deletions of the long arm of chromosome 6 (6q). Twenty of 24 deletions overlapped to define a 4.8-Mb region of mini
Publikováno v:
Experimental Hematology. 42:S61
Autor:
Junia V. Melo, Paul Sinclair, Michael W. Deininger, Letizia Foroni, Amani Sorour, John M. Goldman, Sara A. D. Vieira
Publikováno v:
Genes, chromosomescancer. 32(4)
Expression of BCR/ABL, a constitutively active tyrosine kinase, is a primary event in the pathogenesis of chronic myeloid leukemia (CML) and Ph-positive acute lymphoblastic leukemia (Ph+ALL). Inhibition of the BCR/ABL kinase activity in the BV173 CML