Výsledky vyhledávání - "Amani, Cheikh"

Cross Pharmacological, Biochemical and Computational Studies of a Human Kv3.1b Inhibitor from Androctonus australis Venom

Autor: Rym Benkhalifa, Hager Tabka, Saïd Bendahhou, Sonia Maatoug, Jean-Marie Guigonis, Sylvie Diochot, Zied Landoulsi, Amani Cheikh, Oussema Khamessi

Publikováno v: International Journal of Molecular Sciences
Volume 22
Issue 22
International Journal of Molecular Sciences, Vol 22, Iss 12290, p 12290 (2021)
International Journal of Molecular Sciences, 2021, 22 (22), pp.12290. ⟨10.3390/ijms222212290⟩
International Journal of Molecular Sciences, MDPI, 2021, 22 (22), pp.12290. ⟨10.3390/ijms222212290⟩

International audience; The voltage-gated K+ channels Kv3.1 display fast activation and deactivation kinetics and are known to have a crucial contribution to the fast-spiking phenotype of certain neurons. AahG50, as a natural product extracted from A

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d2bcdf793a39b014236fa9e969861be
https://doi.org/10.3390/ijms222212290

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Xenopus Oocyte’s Conductance for Bioactive Compounds Screening and Characterization

Autor: Noureddine Bouzouaya, Balkiss Bouhaouala-Zahar, Hager Tabka, Yassine Tlili, Rym Benkhalifa, Amani Cheikh, Andrea Santulli

Publikováno v: International Journal of Molecular Sciences, Vol 20, Iss 9, p 2083 (2019)
International Journal of Molecular Sciences
Volume 20
Issue 9

Background: Astaxanthin (ATX) is a lipophilic compound found in many marine organisms. Studies have shown that ATX has many strong biological properties, including antioxidant, antiviral, anticancer, cardiovascular, anti-inflammatory, neuro-protectiv

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0116323d77b5aabd45b748f66215e57a
https://www.mdpi.com/1422-0067/20/9/2083

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First Evidence of Kv3.1b Potassium Channel Subtype Expression during Neuronal Serotonergic 1C11 Cell Line Development

Autor: Hager Tabka, Rym Benkhalifa, Sonia Maatoug, Amani Cheikh, Saïd Bendahhou, Mohamed El Ayeb

Publikováno v: International Journal of Molecular Sciences, Vol 21, Iss 7175, p 7175 (2020)
International Journal of Molecular Sciences
Volume 21
Issue 19
International Journal of Molecular Sciences, MDPI, 2020, 21 (19), pp.7175. ⟨10.3390/ijms21197175⟩

International audience; Kv3.1 channel is abundantly expressed in neurons and its dysfunction causes sleep loss, neurodegenerative diseases and depression. Fluoxetine, a serotonin selective reuptake inhibitor commonly used to treat depression, acts al

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a18e782c06e78b8ec9a31760891b60ef
https://doi.org/10.3390/ijms21197175

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Inhibition of human Kv3.1 current expressed in Xenopus oocytes by the toxic venom fraction of Androctonus australis hector

Autor: Zied Landoulsi, Amani Cheikh, Mohamed El Ayeb, Rym Benkhalifa, Imen Chatti

Publikováno v: Archives of Pharmacal Research. 37:1445-1453

AahG50, the toxic fraction of Androctonus australis hector venom, was studied on human Kv3.1 channels activation, stably expressed in Xenopus oocytes using the two-electrode voltage clamp technique. AahG50 reduced Kv3.1 currents in a reversible conce

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f77934b54d365313b45e87b269dd2eef
https://doi.org/10.1007/s12272-013-0176-5

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Erratum to: Inhibition of human Kv3.1 current expressed in Xenopus oocytes by the toxic venom fraction of Androctonus australis hector

Autor: Amani Cheikh, Rym Benkhalifa, Mohamed El Ayeb, Imen Chatti, Zied Landoulsi

Publikováno v: Archives of Pharmacal Research
Archives of Pharmacal Research, Springer Verlag, 2014, 37, pp.1505. 〈10.1007/s12272-014-0394-5〉

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Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b196e775de59f48846a20da82a3e3abd
https://hal-riip.archives-ouvertes.fr/pasteur-01068211

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A novel depolarizing activity of scorpion venom fraction M1 due to activation of skeletal muscle nicotinic receptors

Autor: Rym Benkhalifa, Christian Cognard, Guy Raymond, Mohamed El Ayeb, Amani Cheikh, Daniel Potreau

Publikováno v: Toxicon
Toxicon, Elsevier, 2007, 49 (1), pp.117-22. ⟨10.1016/j.toxicon.2006.09.011⟩

A depolarizing activity following interaction with nicotinic acetylcholine receptors (nAchRs) in skeletal muscle cells, was observed for the first time in the non-toxic venom fraction (M1) of the yellow scorpion Buthus occitanus tunetanus (Bot). The

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d42df15cf1cc7045ed3715c12ce337de
https://hal-riip.archives-ouvertes.fr/pasteur-00614376

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Depression of cardiac L-type calcium current by a scorpion venom fraction M1 following muscarinic receptors interaction involving adenylate cyclase pathway

Autor: Jocelyn Bescond, Guy Raymond, Daniel Potreau, Amani Cheikh, Rym Benkhalifa, Christian Cognard, Mohamed El Ayeb

Publikováno v: Toxicon
Toxicon, Elsevier, 2006, 48 (4), pp.373-87. ⟨10.1016/j.toxicon.2006.06.016⟩

The effects of a non-toxic fraction, called M1, from Buthus occitanus tunetanus (Bot) scorpion were studied on rat cardiac contraction and calcium transient and current. A decrease in both rate and tension on isolated intact hearts as well as in calc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d4ca54f9e941ea6b5c92d6a413b82ea
https://hal-riip.archives-ouvertes.fr/pasteur-00614365

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A new type of scorpion Na+-channel-toxin-like polypeptide active on K+ channels

Autor: Manel Ben Aissa, Amani Cheikh, Mohamed El Ayeb, Najet Srairi-Abid, Joseba Iñaki Guijarro, Rym Benkhalifa, Massimo Mantegazza, Muriel Delepierre, Pierre Yves Haumont

Publikováno v: Biochemical Journal
Biochemical Journal, Portland Press, 2005, 388, pp.455-464. ⟨10.1042/BJ20041407⟩
Biochemical Journal, 2005, 388, pp.455-464. ⟨10.1042/BJ20041407⟩

We have purified and characterized two peptides, named KAaH1 and KAaH2 (AaH polypeptides 1 and 2 active on K+ channels, where AaH stands for Androctonus australis Hector), from the venom of A. australis Hector scorpions. Their sequences contain 58 am

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f52e0583423c7dfdf9127ce917d3da01
https://europepmc.org/articles/PMC1138952/

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