Dendritic Cells Require TMEM176A/B Ion Channels for Optimal MHC Class II Antigen Presentation to Naive CD4 + T Cells

Autor: Saeed Abdu Rahiman, Melanie Lancien, Amandine Even, Séverine Remy, Maria-Cristina Cuturi, Veronica De Simone, Lucile Gueno, Elise Chiffoleau, Sonia Salle, Aurélie Moreau, Geraldine Bienvenu, Steven M. Kerfoot, Alice Molle, Gaelle Beriou, Flora Coulon, Régis Josien, Magalie Feyeux, Franck Perez, Susan Chan, Cynthia Fourgeux, Emmanuel Merieau, Gianluca Matteoli, Peggy Kirstetter, Laurence Bouchet-Delbos, Jeremie Poschmann, Cédric Louvet, Gaelle Boncompain

Publikováno v: Journal of Immunology
Journal of Immunology, Publisher : Baltimore : Williams & Wilkins, c1950-. Latest Publisher : Bethesda, MD : American Association of Immunologists, 2021, 207 (2), pp.421-435. ⟨10.4049/jimmunol.2000498⟩
Journal of Immunology, 2021, 207 (2), pp.421-435. ⟨10.4049/jimmunol.2000498⟩

Intracellular ion fluxes emerge as critical actors of immunoregulation but still remain poorly explored. In this study, we investigated the role of the redundant cation channels TMEM176A and TMEM176B (TMEM176A/B) in retinoic acid–related orphan rec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e126d8e7d0d0168c2845b097dd19d0f1
https://hal.archives-ouvertes.fr/hal-03375841

Preclinical Assessment of Autologous Tolerogenic Dendritic Cells From End-stage Renal Disease Patients

Autor: Laurence Bouchet-Delbos, Régis Josien, Soraya Saiagh, Emilie Varey, Amandine Even, Gilles Blancho, Maria-Cristina Cuturi, Cécile Braudeau, Aurélie Moreau, Brigitte Dréno, Sylvain Bercegeay

Publikováno v: Transplantation
Transplantation, 2020, 105 (4), pp.832-841. ⟨10.1097/tp.0000000000003315⟩

Background Kidney transplantation is the therapeutic of choice for patients suffering from kidney failure. Whilst immunosuppressive drugs can control graft rejection, their use is associated with increased infections and cancer, and they do not effec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3edbe1b409d6efcaf89fd98bd03c6ce
https://doi.org/10.1097/tp.0000000000003315