Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Amandine, Caillaud"'
Autor:
Meryl Roudaut, Amandine Caillaud, Zied Souguir, Lise Bray, Aurore Girardeau, Antoine Rimbert, Mikaël Croyal, Gilles Lambert, Murielle Patitucci, Gaspard Delpouve, Élodie Vandenhaute, Cédric Le May, Nathalie Maubon, Bertrand Cariou, Karim Si‐Tayeb
Publikováno v:
Bioengineering & Translational Medicine, Vol 9, Iss 4, Pp n/a-n/a (2024)
Abstract The liver plays a key role in the metabolism of lipoproteins, controlling both production and catabolism. To accelerate the development of new lipid‐lowering therapies in humans, it is essential to have a relevant in vitro study model avai
Externí odkaz:
https://doaj.org/article/53835cc8b72d4f2bb753a350085e434f
Autor:
Amandine Caillaud, Lise Bray, Aurore Girardeau, Zoé Begué-Racapé, Lucie Vince, Murielle Patitucci, Cédric Le May, Gilles Lambert, Bertrand Cariou, Antoine Rimbert
Publikováno v:
Stem Cell Research, Vol 72, Iss , Pp 103205- (2023)
Elevated circulating lipoprotein(a) (Lp(a)) is a genetically determined risk factor for coronary artery disease and aortic valve stenosis (Tsimikas, 2017). Importantly, the LPA gene, which encodes the apolipoprotein(a) (protein-component of Lp(a)), i
Externí odkaz:
https://doaj.org/article/e345a600cf6a4dfa9de0005f00980a21
Autor:
Marine Delamare, Amandine Le Roy, Mathilde Pacault, Loïc Schmitt, Céline Garrec, Nada Maaziz, Matti Myllykoski, Antoine Rimbert, Valéna Karaghiannis, Bernard Aral, Mark Catherwood, Fabrice Airaud, Lamisse Mansour-Hendili, David Hoogewijs, Edoardo Peroni, Salam Idriss, Valentine Lesieur, Amandine Caillaud, Karim Si-Tayeb, Caroline Chariau, Anne Gaignerie, Minke Rab, Torsten Haferlach, Manja Meggendorfer, Stéphane Bézieau, Andrea Benetti, Nicole Casadevall, Pierre Hirsch, Christian Rose, Mathieu Wemeau, Frédéric Galacteros, Bruno Cassinat, Beatriz Bellosillo, Celeste Bento, Richard van Wijk, Petro E. Petrides, Maria Luigia Randi, Mary Frances McMullin, Peppi Koivunen, François Girodon, Betty Gardie, ECYT consortium
Publikováno v:
Haematologica, Vol 108, Iss 11 (2023)
Hereditary erythrocytosis is a rare hematologic disorder characterized by an excess of red blood cell production. Here we describe a European collaborative study involving a collection of 2,160 patients with erythrocytosis sequenced in ten different
Externí odkaz:
https://doaj.org/article/3f9446a9e07d45d496f7af7a30c39bce
Autor:
Amandine Caillaud, Antoine Lévêque, Aurélie Thédrez, Aurore Girardeau, Robin Canac, Lise Bray, Manon Baudic, Julien Barc, Nathalie Gaborit, Guillaume Lamirault, Betty Gardie, Salam Idriss, Antoine Rimbert, Cédric Le May, Bertrand Cariou, Karim Si-Tayeb
Publikováno v:
STAR Protocols, Vol 3, Iss 4, Pp 101680- (2022)
Summary: This manuscript proposes an efficient and reproducible protocol for the generation of genetically modified human induced pluripotent stem cells (hiPSCs) by genome editing using CRISPR-Cas9 technology. Here, we describe the experimental strat
Externí odkaz:
https://doaj.org/article/5abbb31c95e14d87806374946c01203d
Autor:
Lise Bray, Amandine Caillaud, Aurore Girardeau, Murielle Patitucci, Cédric Le May, Bertrand Cariou, Antoine Rimbert
Publikováno v:
Stem Cell Research, Vol 60, Iss , Pp 102721- (2022)
Dyslipidemia is a key modifiable causal risk factor involved in the development of atherosclerotic cardiovascular disease. Recently, the G protein-coupled receptor 146 (GPR146), a member of the G-coupled protein receptors’ family, has been shown to
Externí odkaz:
https://doaj.org/article/91ae641bbee14723a56feea438de6d5d
Autor:
Aurore Girardeau, Diane Atticus, Robin Canac, Bastien Cimarosti, Amandine Caillaud, Caroline Chariau, Floriane Simonet, Bertrand Cariou, Flavien Charpentier, Jean-Baptiste Gourraud, Vincent Probst, Nadjet Belbachir, Laurence Jesel, Patricia Lemarchand, Julien Barc, Richard Redon, Nathalie Gaborit, Guillaume Lamirault
Publikováno v:
Stem Cell Research, Vol 59, Iss , Pp 102647- (2022)
Four human induced pluripotent stem cell (hiPSC) lines have been generated from healthy control European donors, and validated. This resource represents a useful tool for stem cell-based research, as references for developmental studies and disease m
Externí odkaz:
https://doaj.org/article/e451cd47ad734a8bbbb3a51ae1564c13
Autor:
Robin Canac, Amandine Caillaud, Bastien Cimarosti, Aurore Girardeau, Hanan Hamamy, Bruno Reversade, Carine Bonnard, Zeina R. Al Sayed, Laurent David, Jeremie Poschmann, Patricia Lemarchand, Guillaume Lamirault, Nathalie Gaborit
Publikováno v:
Stem Cell Research, Vol 58, Iss , Pp 102627- (2022)
Studies on animal models have shown that Irx5 is an important regulator of cardiac development and that it regulates ventricular electrical repolarization gradient in the adult heart. Mutations in IRX5 have also been linked in humans to cardiac condu
Externí odkaz:
https://doaj.org/article/a5200d83fcab486da903e7e399073f5b
Autor:
Karim Si-Tayeb, Salam Idriss, Benoite Champon, Amandine Caillaud, Matthieu Pichelin, Lucie Arnaud, Patricia Lemarchand, Cédric Le May, Kazem Zibara, Bertrand Cariou
Publikováno v:
Disease Models & Mechanisms, Vol 9, Iss 1, Pp 81-90 (2016)
Proprotein convertase subtilisin kexin type 9 (PCSK9) is a critical modulator of cholesterol homeostasis. Whereas PCSK9 gain-of-function (GOF) mutations are associated with autosomal dominant hypercholesterolemia (ADH) and premature atherosclerosis,
Externí odkaz:
https://doaj.org/article/25a1d3f503b14c22b8fd68999092740d
Autor:
E. Luce, Etienne Bur, Anne Dubart-Kupperschmitt, Bertrand Cariou, Amandine Caillaud, Antonietta Messina, Jean-Charles Duclos-Vallée, Karim Si-Tayeb
Publikováno v:
médecine/sciences. 37:902-909
L’étude et la compréhension de l’organogenèse du foie ont permis le développement de protocoles de différenciation des cellules souches pluripotentes afin de pallier le manque de cellules primaires, offrant ainsi une source quasi illimitée
Autor:
Antoine, Rimbert, Ming W, Yeung, Nawar, Dalila, Chris H L, Thio, Haojie, Yu, Natalia, Loaiza, Federico, Oldoni, Adriaan, van der Graaf, Siqi, Wang, M Abdullah, Said, Lisanne L, Blauw, Aurore, Girardeau, Lise, Bray, Amandine, Caillaud, Vincent W, Bloks, Marie, Marrec, Philippe, Moulin, Patrick C N, Rensen, Bart, van de Sluis, Harold, Snieder, Mathilde, Di Filippo, Pim, van der Harst, Anne, Tybjaerg-Hansen, Philip, Zimmerman, Bertrand, Cariou, Jan Albert, Kuivenhoven
Publikováno v:
Arteriosclerosis, thrombosis, and vascular biology. 42(10)
In mice, GPR146 (G-protein-coupled receptor 146) deficiency reduces plasma lipids and protects against atherosclerosis. Whether these findings translate to humans is unknown.Common and rare genetic variants in theIn the UK Biobank, carriers of the co