A new strategy to count and sort neutrophil‐derived extracellular vesicles: Validation in infectious disorders

Autor: Amandine Bonifay, Stéphane Robert, Belinda Champagne, Paul‐Rémi Petit, Aude Eugène, Corinne Chareyre, Anne‐Claire Duchez, Mélanie Vélier, Shirley Fritz, Loris Vallier, Romaric Lacroix, Françoise Dignat‐George

Publikováno v: Journal of Extracellular Vesicles, Vol 11, Iss 4, Pp n/a-n/a (2022)

Abstract Newly recognized polymorphonuclear neutrophil (PMNs) functions include the ability to release subcellular mediators such as neutrophil‐derived extracellular vesicles (NDEVs) involved in immune and thrombo‐inflammatory responses. Elevatio

Externí odkaz: https://doaj.org/article/12117ce56d534d6fac6a5cdf99098b32

Blood coagulation and beyond

Autor: Asim Cengiz Akbulut, Ryanne A. Arisz, Constance C. F. M. J. Baaten, Gaukhar Baidildinova, Aarazo Barakzie, Rupert Bauersachs, Jur ten Berg, Wout W. A. van den Broek, H. C. de Boer, Amandine Bonifay, Vanessa Bröker, Richard J. Buka, Hugo ten Cate, Arina J. ten Cate-Hoek, S. Cointe, Ciro De Luca, Ilaria De Simone, Rocio Vacik Diaz, Françoise Dignat-George, Kathleen Freson, Giulia Gazzaniga, Eric C. M. van Gorp, Anxhela Habibi, Yvonne M. C. Henskens, Aaron F. J. Iding, Abdullah Khan, Gijsje H. Koenderink, Akhil Konkoth, Romaric Lacroix, Trisha Lahiri, Wilbur Lam, Rachel E. Lamerton, Roberto Lorusso, Qi Luo, Coen Maas, Owen J. T. McCarty, Paola E. J. van der Meijden, Joost C. M. Meijers, Adarsh K. Mohapatra, Neta Nevo, Alejandro Pallares Robles, Philippe Poncelet, Christoph Reinhardt, Wolfram Ruf, Ronald Saraswat, Claudia Schönichen, Roger Schutgens, Paolo Simioni, Stefano Spada, Henri M. H. Spronk, Karlygash Tazhibayeva, Jecko Thachil, L. Vallier, Alicia Veninga, Peter Verhamme, Chantal Visser, Steve P. Watson, Philip Wenzel, Ruth A. L. Willems, Anne Willers, Pengyu Zhang, Konstantinos Zifkos, Anton Jan van Zonneveld

Publikováno v: Thrombosis and Haemostasis. Georg Thieme Verlag
Thrombosis and haemostasis. Schattauer GmbH

The Fourth Maastricht Consensus Conference on Thrombosis included the following themes. Theme 1: The “coagulome” as a critical driver of cardiovascular disease. Blood coagulation proteins also play divergent roles in biology and pathophysiology,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd95dbe34ad6519ebc8bd48af7de3f1d
https://cris.maastrichtuniversity.nl/en/publications/24c748a9-e928-4dca-9834-d6c9dad4cd6a

Extracellular vesicles-associated biomarkers: Opportunities and challenges in cardiovascular diseases and cancer

Autor: Amandine, Bonifay, Sandra, Ghayad, Romaric, Lacroix, Françoise, Dignat-George

Publikováno v: médecine/sciences
médecine/sciences, 2021, 37 (12), pp.1158-1165. ⟨10.1051/medsci/2021208⟩

Cardiovascular diseases and cancer are the leading causes of mortality and morbidity in the world. The search for pertinent biomarkers for risk stratification and treatment monitoring is a challenge. Rapid advances in the identification of the molecu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::1ed647a7340b0e52d1533dd8f5b38c03
https://hal.science/hal-03498240/file/msc200723.pdf

Dissemination of extreme levels of extracellular vesicles: tissue factor activity in patients with severe COVID-19

Autor: Françoise Dignat-George, Evelyne Abdili, Raphael Cauchois, Gilles Kaplanski, Christophe Guervilly, Léa Pietri, Laurent Papazian, Romaric Lacroix, Laurent Arnaud, Florence Sabatier, Jacques Albanèse, Thomas Robert, Amandine Bonifay, Mélanie Velier, Guillaume Lano, Stéphane Burtey

Publikováno v: Blood Advances
Blood Advances, 2021, 5 (3), pp.628-634. ⟨10.1182/bloodadvances.2020003308⟩
Blood Advances, The American Society of Hematology, 2021, 5 (3), pp.628-634. ⟨10.1182/bloodadvances.2020003308⟩

Key Points EV-TF activity is dramatically increased in patients with severe COVID-19 and is associated with an increased thrombotic risk. Compared with patients with septic shock, those with severe COVID-19 display a distinct EV profile with higher p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13278c6ae35601e17e6177fc6e352c24
https://pubmed.ncbi.nlm.nih.gov/33560376

A new assay to evaluate microvesicle plasmin generation capacity: validation in disease with fibrinolysis imbalance

Autor: Romain Armand, Stéphane Robert, Karim Harti Souab, Sylvie Cointe, Loris Vallier, Jacques Albanèse, Tarik Bouriche, Philippe Poncelet, Coralie Judicone, Romaric Lacroix, Amandine Bonifay, Françoise Dignat-George

Publikováno v: Journal of Extracellular Vesicles
Journal of Extracellular Vesicles, Taylor & Francis, 2018, 7 (1), pp.1494482. ⟨10.1080/20013078.2018.1494482⟩
Journal of Extracellular Vesicles 1 (7), . (2018)
Journal of Extracellular Vesicles, Vol 7, Iss 1 (2018)
Journal of Extracellular Vesicles, 2018, 7 (1), pp.1494482. ⟨10.1080/20013078.2018.1494482⟩

International audience; Among extracellular vesicles, leukocyte-derived microvesicles (LMVs) have emerged as complex vesicular structures. Primarily identified as procoagulant entities, they were more recently ascribed to plasmin generation capacity

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebe273428b8ab6062ad6a8cb52515f45
https://hal-amu.archives-ouvertes.fr/hal-02060265/document