Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Amandeep, Girdhar"'
Autor:
Miyuki Hayashi, Amandeep Girdhar, Ying-Hui Ko, Kevin M. Kim, Jacquelyn A. DePierro, Joseph R. Buchler, Nikhita Arunprakash, Aditya Bajaj, Gino Cingolani, Lin Guo
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-20 (2024)
Abstract Importin β-superfamily nuclear import receptors (NIRs) mitigate mislocalization and aggregation of RNA-binding proteins (RBPs), like FUS and TDP-43, which are implicated in neurodegenerative diseases. NIRs potently disaggregate RBPs by reco
Externí odkaz:
https://doaj.org/article/5cf3c1d8b89a4dc78f404d31b0c86da0
Autor:
Amandeep Girdhar, Lin Guo
Publikováno v:
Biology, Vol 11, Iss 7, p 1009 (2022)
RNA-binding proteins (RBPs) with a low-complexity prion-like domain (PLD) can undergo aberrant phase transitions and have been implicated in neurodegenerative diseases such as ALS and FTD. Several nuclear RBPs mislocalize to cytoplasmic inclusions in
Externí odkaz:
https://doaj.org/article/47fae1944bf341b0a329734390c40c59
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 12 (2019)
TAR DNA binding protein 43 (TDP-43) is a versatile RNA/DNA binding protein involved in RNA-related metabolism. Hyper-phosphorylated and ubiquitinated TDP-43 deposits act as inclusion bodies in the brain and spinal cord of patients with the motor neur
Externí odkaz:
https://doaj.org/article/ffc3826b175a4d0db983b19f9ebe3be3
Autor:
Meenakshi Verma, Amandeep Girdhar, Basant Patel, Nirmal K. Ganguly, Ritushree Kukreti, Vibha Taneja
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 11 (2018)
Interactions amongst different amyloid proteins have been proposed as a probable mechanism of aggregation and thus an important risk factor for the onset as well as progression of various neurodegenerative disorders including Alzheimer's, Parkinson's
Externí odkaz:
https://doaj.org/article/7b2bf04c64514bdeba33a136ebe802e3
Autor:
Junli, Gao, Quinlan T, Mewborne, Amandeep, Girdhar, Udit, Sheth, Alyssa N, Coyne, Ritika, Punathil, Bong Gu, Kang, Morgan, Dasovich, Austin, Veire, Mariely, DeJesus Hernandez, Shuaichen, Liu, Zheng, Shi, Ruxandra, Dafinca, Elise, Fouquerel, Kevin, Talbot, Tae-In, Kam, Yong-Jie, Zhang, Dennis, Dickson, Leonard, Petrucelli, Marka, van Blitterswijk, Lin, Guo, Ted M, Dawson, Valina L, Dawson, Anthony K L, Leung, Thomas E, Lloyd, Tania F, Gendron, Jeffrey D, Rothstein, Ke, Zhang
Publikováno v:
Science translational medicine. 14(662)
Arginine-rich dipeptide repeat proteins (R-DPRs), abnormal translational products of a GGGGCC hexanucleotide repeat expansion in
Publikováno v:
Bio-Protocol, Vol 7, Iss 15 (2017)
The yeast Saccharomyces cerevisiae (S. cerevisiae) harboring ade1 or ade2 mutations manifest red colony color phenotype on rich yeast medium YPD. In these mutants, intermediate metabolites of adenine biosynthesis pathway are accumulated. Accumulated
Externí odkaz:
https://doaj.org/article/f756decc535d44ec9d3237468ace3311
Autor:
Gembali Raju, Amandeep Girdhar, Waghela Deeksha, Suman Abhishek, Vidhya Bharathi, Eerappa Rajakumara, Sandeep Singh, Basant K. Patel, Ganesan Prabusankar, Usha Mahawar, Vikas Ramyagya Tiwari
Publikováno v:
International Journal of Biological Macromolecules. 147:117-130
TDP-43 is an RNA/DNA-binding protein which is also implicated in the pathogenesis of amyotrophic lateral sclerosis (ALS) disease. TDP-43's cytoplasmic mis-localization, liquid-liquid phase separation (LLPS) due to RNA depletion and aggregation, are p
Publikováno v:
TDP-43 and Neurodegeneration
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aa0f3d1f259bd2dee3dc6f85127494bc
https://doi.org/10.1016/b978-0-12-820066-7.00002-3
https://doi.org/10.1016/b978-0-12-820066-7.00002-3
Autor:
Nikita Admane, Md Sheeraz Anwar, Pasha Apontes, Vidhya Bharathi, Oxana V. Galzitskaya, Amandeep Girdhar, Mohd Maksuf Ul Haque, Manoj Kumar Jaiswal, Himanshi Kukrety, Vijay Kumar, Md Zubbair Malik, Basant K. Patel, Samir Rahman, Saurabh Kumar Sharma, R.K. Brojen Singh, Shiv Pratap Singh Yadav, Ankit Srivastava, Anil Kumar Tomar, Nidhi Verma, Savita Yadav
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::478ec3c44281f490218faf9870da9f3f
https://doi.org/10.1016/b978-0-12-820066-7.01002-x
https://doi.org/10.1016/b978-0-12-820066-7.01002-x
Autor:
Amandeep, Girdhar, Vidhya, Bharathi, Vikas Ramyagya, Tiwari, Suman, Abhishek, Waghela, Deeksha, Usha Saraswat, Mahawar, Gembali, Raju, Sandeep Kumar, Singh, Ganesan, Prabusankar, Eerappa, Rajakumara, Basant K, Patel
Publikováno v:
International journal of biological macromolecules. 147
TDP-43 is an RNA/DNA-binding protein which is also implicated in the pathogenesis of amyotrophic lateral sclerosis (ALS) disease. TDP-43's cytoplasmic mis-localization, liquid-liquid phase separation (LLPS) due to RNA depletion and aggregation, are p