Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Amanda Y Chong"'
Autor:
Weerachai Jaratlerdsiri, Janine Deakin, Ricardo M Godinez, Xueyan Shan, Daniel G Peterson, Sylvain Marthey, Eric Lyons, Fiona M McCarthy, Sally R Isberg, Damien P Higgins, Amanda Y Chong, John St John, Travis C Glenn, David A Ray, Jaime Gongora
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e114631 (2014)
The major histocompatibility complex (MHC) is a dynamic genome region with an essential role in the adaptive immunity of vertebrates, especially antigen presentation. The MHC is generally divided into subregions (classes I, II and III) containing gen
Externí odkaz:
https://doaj.org/article/4b4f6cf4129a43dc8c740bb4d15544a2
Autor:
Alexander J. Mentzer, Nicole Brenner, Naomi Allen, Thomas J. Littlejohns, Amanda Y. Chong, Adrian Cortes, Rachael Almond, Michael Hill, Simon Sheard, Gil McVean, UKB Infection Advisory Board, Rory Collins, Adrian V. S. Hill, Tim Waterboer
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
Here, the authors design a multiplex serology platform to quantitatively measure antibodies against 20 infectious agents in UK Biobank participants and confirm associations of antibody responses with sociodemographic characteristics, HLA genetic vari
Externí odkaz:
https://doaj.org/article/086909a39d6a4b8bbe11b080ee7709f7
Autor:
Andrés Jiménez-Kaufmann, Amanda Y. Chong, Adrián Cortés, Consuelo D. Quinto-Cortés, Selene L. Fernandez-Valverde, Leticia Ferreyra-Reyes, Luis Pablo Cruz-Hervert, Santiago G. Medina-Muñoz, Mashaal Sohail, María J. Palma-Martinez, Gudalupe Delgado-Sánchez, Norma Mongua-Rodríguez, Alexander J. Mentzer, Adrian V. S. Hill, Hortensia Moreno-Macías, Alicia Huerta-Chagoya, Carlos A. Aguilar-Salinas, Michael Torres, Hie Lim Kim, Namrata Kalsi, Stephan C. Schuster, Teresa Tusié-Luna, Diego Ortega Del-Vecchyo, Lourdes García-García, Andrés Moreno-Estrada
Publikováno v:
Frontiers in Genetics, Vol 12 (2022)
Current Genome-Wide Association Studies (GWAS) rely on genotype imputation to increase statistical power, improve fine-mapping of association signals, and facilitate meta-analyses. Due to the complex demographic history of Latin America and the lack
Externí odkaz:
https://doaj.org/article/f94af263ed674e53806cd4fa4ebf32e7
Autor:
Gil McVean, Adrian Cortes, Simon Sheard, Alexander J. Mentzer, Hill Avs., Thomas J. Littlejohns, Naomi E. Allen, Nicole Brenner, R Almond, Tim Waterboer, Rory Collins, Michael Hill, Amanda Y. Chong
BackgroundCertain infectious agents are recognised causes of cancer and potentially other chronic diseases. Identifying associations and understanding pathological mechanisms involving infectious agents and subsequent chronic disease risk will be pos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4e80cc588f70292ab1093749f31146c
http://hdl.handle.net/10029/626407
http://hdl.handle.net/10029/626407
Autor:
Alexander J. Mentzer, Alexander T. Dilthey, Martin Pollard, Deepti Gurdasani, Emre Karakoc, Tommy Carstensen, Allan Muhwezi, Clare Cutland, Amidou Diarra, Ricardo da Silva Antunes, Sinu Paul, Gaby Smits, Susan Wareing, HwaRan Kim, Cristina Pomilla, Amanda Y. Chong, Debora Y.C. Brandt, Rasmus Nielsen, Samuel Neaves, Nicolas Timpson, Austin Crinklaw, Cecilia S. Lindestam Arlehamn, Anna Rautanen, Dennison Kizito, Tom Parks, Kathryn Auckland, Kate E. Elliott, Tara Mills, Katie Ewer, Nick Edwards, Segun Fatumo, Sarah Peacock, Katie Jeffery, Fiona R.M. van der Klis, Pontiano Kaleebu, Pandurangan Vijayanand, Bjorn Peters, Alessandro Sette, Nezih Cereb, Sodiomon Sirima, Shabir A. Madhi, Alison M. Elliott, Gil McVean, Adrian V.S. Hill, Manjinder S. Sandhu
How human genetic variation contributes to vaccine immunogenicity and effectiveness is unclear, particularly in infants from Africa. We undertook genome-wide association analyses of eight vaccine antibody responses in 2,499 infants from three African
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6d03a43aecccb408d4ee8b3d67cc171a
https://doi.org/10.1101/2022.11.24.22282715
https://doi.org/10.1101/2022.11.24.22282715
Autor:
Mashaal Sohail, Amanda Y. Chong, Consuelo D. Quinto-Cortes, María J. Palma-Martínez, Aaron Ragsdale, Santiago G. Medina-Muñoz, Carmina Barberena-Jonas, Guadalupe Delgado-Sánchez, Luis Pablo Cruz-Hervert, Leticia Ferreyra-Reyes, Elizabeth Ferreira-Guerrero, Norma Mongua-Rodríguez, Andrés Jimenez-Kaufmann, Hortensia Moreno-Macías, Carlos A. Aguilar-Salinas, Kathryn Auckland, Adrián Cortés, Víctor Acuña-Alonzo, Alexander G. Ioannidis, Christopher R. Gignoux, Genevieve L. Wojcik, Selene L. Fernández-Valverde, Adrian V.S. Hill, María Teresa Tusié-Luna, Alexander J. Mentzer, John Novembre, Lourdes García-García, Andrés Moreno-Estrada
Latin America continues to be severely underrepresented in genomics research, and fine-scale genetic histories as well as complex trait architectures remain hidden due to the lack of Big Data. To fill this gap, the Mexican Biobank project genotyped 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7b7dfd5bc2e5e24739ab44dc3536ed62
https://doi.org/10.1101/2022.07.11.499652
https://doi.org/10.1101/2022.07.11.499652
Autor:
Alexander J, Mentzer, Nicole, Brenner, Naomi, Allen, Thomas J, Littlejohns, Amanda Y, Chong, Adrian, Cortes, Rachael, Almond, Michael, Hill, Simon, Sheard, Gil, McVean, Rory, Collins, Adrian V S, Hill, David, Wyllie
Certain infectious agents are recognised causes of cancer and other chronic diseases. To understand the pathological mechanisms underlying such relationships, here we design a Multiplex Serology platform to measure quantitative antibody responses aga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0a4e59d87981b214cf8096f053d655d
https://doi.org/10.1038/s41467-022-29307-3
https://doi.org/10.1038/s41467-022-29307-3
Autor:
Adrian V. S. Hill, Christian Hammer, Jacques Fellay, Peter Vollenweider, S. Rüeger, Flavia Hodel, Z. M. Xu, Nicole Brenner, Christian W. Thorball, Pedro Marques-Vidal, Olivier Naret, Hannelore Ehrenreich, Alexander J. Mentzer, Amanda Y. Chong, Petar Scepanovic, Tim Waterboer, Noemi Bender, Martin Begemann
Human polyomaviruses are widespread in human populations and are able to cause severe disease in immunocompromised individuals. There remains an incomplete understanding of the potential impact of human genetic variation on inter-individual responses
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2c6c9161bbfd3bebb60b44a857fbb567
https://doi.org/10.1101/2020.11.02.20224402
https://doi.org/10.1101/2020.11.02.20224402
Autor:
Marco Moroldo, Sylvain Marthey, Núria Mach, Amanda Y. Chong, Claire Rogel-Gaillard, Simon Y. W. Ho, Carol Lee, Jérôme Lecardonnel, Per Wahlberg, Jaime Gongora, Alvaro Perdomo-Sabogal, Jordi Estellé
Publikováno v:
Immunogenetics
Immunogenetics, Springer Verlag, 2018, 70 (6), pp.401-417. ⟨10.1007/s00251-017-1048-9⟩
Immunogenetics, Springer Verlag, 2018, 70 (6), pp.401-417. ⟨10.1007/s00251-017-1048-9⟩
International audience; The major histocompatibility complex (MHC) is a key genomic model region for understanding the evolution of gene families and the co-evolution between host and pathogen. To date, MHC studies have mostly focused on species from
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea5dc99b752cee61bc7a4ee820972be1
https://doi.org/10.1007/s00251-017-1048-9
https://doi.org/10.1007/s00251-017-1048-9
Publikováno v:
Virus Genes. 50:329-332
Endogenous retroviruses (ERVs) are one of many families of transposable elements present in vertebrate genomes. We have examined the ERV complement of the freshwater crocodile (Crocodylus johnstoni) in order to investigate the diversity of ERVs prese