Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Amanda Weyers"'
Autor:
Mitchell Laughlin, Amanda Weyers, Elizabeth Dudley, Adriana Serrata, Elizabeth A. Leadbetter, Devon A. Shipp, Rachel Fromme, Jennifer Yates, Briana Hauff Salas, Robert J. Linhardt, Travis Shute, Jianjun Miao, Chloe Mesa, Brandy Vincent, Olivia Z. Durham, Eyal Amiel, Paula A. Lanthier, Noran Alam, Emilie E. Vomhof-DeKrey, Daniel Angel, Kelly L. Nash, Katya Mohrs
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 206(8)
CD4+ T cells enable the critical B cell humoral immune protection afforded by most effective vaccines. We and others have recently identified an alternative source of help for B cells in mice, invariant NK T (iNKT) cells. iNKT cells are innate glycol
Autor:
Themis R. Kyriakides, Lise Tchouta, Amanda Weyers, John M. Tarbell, Wei Wu, Robert J. Linhardt, Sumati Sundaram, David Slattery, Liqiong Gui, Charles T. Tuggle, Chao Cai, Laura E. Niklason, Sashka Dimitrievska, Tylee Lin, Jenna L. Balestrini
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 36:1847-1853
Objective— It is widely accepted that the presence of a glycosaminoglycan-rich glycocalyx is essential for endothelialized vasculature health; in fact, a damaged or impaired glycocalyx has been demonstrated in many vascular diseases. Currently, the
Autor:
Amanda Weyers, Ashley L. Gard, Mehmet H. Kural, Alan P. Kypson, Nina Kristofik, Sumati Sundaram, Liping Zhao, Guangxin Li, Sashka Dimitrievska, Joseph A. Madri, Chao Cai, Themis R. Kyriakides, Lingfeng Qin, Hualong Bai, Laura E. Niklason, Tylee Lin, Yifan Yuan, Kota Yamamoto, Wei Wu, Robert J. Linhardt, Juan Wang
Publikováno v:
Advanced Functional Materials. 30:1908963
Autor:
Lingyun Li, Kyung Bok Lee, Amanda Weyers, Eun Ji Joo, Leyla Gasimli, Guoyun Li, Robert J. Linhardt, Won Jun Choi
Publikováno v:
OMICS: A Journal of Integrative Biology. 18:231-241
Glycans play a critical role in physiological and pathological processes through interaction with a variety of ligands. Altered expression and dysregulation of these molecules can cause aberrant cellular function such as malignancy. Glycomics provide
Autor:
Kyung Bok Lee, Yong-Seok Kim, Amanda Weyers, Robert J. Linhardt, Bo Yang, Sang-Eok Lee, Fuming Zhang, Jong-Hwan Park, Sun-Moon Kim
Publikováno v:
Glycoconjugate Journal. 30:701-707
Glycosaminoglycans (GAGS) are anionic, linear, polysaccharides involved in cell signaling. The GAG content, composition and structure of human tissue have been suggested to play a role in cancer and might provide useful diagnostic or prognostic marke
Autor:
Amanda Weyers, Robert J. Linhardt
Publikováno v:
FEBS Journal. 280:2511-2522
Proteoglycans, comprised of a core protein to which glycosaminoglycan chains are covalently linked, are an important structural and functional family of macromolecules found in the extracellular matrix. Advances in our understanding of biological int
Autor:
Amanda Weyers, Julie M. Beaudet, Bo Yang, Robert J. Linhardt, Kemal Solakyildirim, Fuming Zhang, Chao Cai
Publikováno v:
Carbohydrate Polymers. 87:822-829
Chondroitin sulfate-E (chondroitin-4,6-disulfate) was prepared from chondroitin sulfate-A (chondroitin-4-sulfate) by regioselective sulfonation, performed using trimethylamine sulfur trioxide in formamide under argon. The structure of semi-synthetic
Autor:
Amanda Weyers, Bo Yang, Kemal Solakyildirim, Julie M. Beaudet, Fuming Zhang, Majde Takieddin, Shaker A. Mousa, Robert J. Linhardt
Publikováno v:
Journal of Pharmaceutical Sciences. 100:3396-3404
The stability of a formulated heparin was examined during its sterilization by autoclaving. A new method to follow loss in heparin binding to the serine protease inhibitor, antithrombin III, and the serine protease, thrombin, and was developed using
Autor:
K. V. Lakshmi, Amanda Weyers, Ashley Meenaghan, Ruchira Chatterjee, Sergey Milikisiyants, Christopher S. Coates
Publikováno v:
The Journal of Physical Chemistry B. 114:10905-10911
The solar water-splitting protein complex, photosystem II, catalyzes the light-driven oxidation of water to dioxygen in Nature. The four-electron oxidation reaction of water occurs at the tetranuclear manganese—calcium—oxo catalytic cl uster that
Autor:
Jianjun Miao, Go Hatachi, Themis R. Kyriakides, Laura E. Niklason, Amanda Weyers, Jenna L. Balestrini, Robert J. Linhardt, David Spiegel, Sumati Sundaram, Tylee Lin, Guoyun Li, Sashka Dimitrievska, Chao Cai
Publikováno v:
Acta biomaterialia. 13
A novel method enabling the engineering of a dense and appropriately oriented heparin-containing layer on decellularized aortas has been developed. Amino groups of decellularized aortas were first modified to azido groups using 3-azidobenzoic acid. A