Sequencing‐based microsatellite instability testing using as few as six markers for high‐throughput clinical diagnostics

Autor: Ciaron McAnulty, Ghanim Alhilal, Michael S. Jackson, Richard Gallon, Harsh Sheth, Sira Moreno Laguna, Gillian M. Borthwick, Angel Alonso, John Burn, Mauro Santibanez-Koref, Amanda Waltham, C Hayes, Helena L. Spiewak, Lisa Redford, Osagie G. Izuogu, Mark J. Arends, O. O'brien, Anca Oniscu

Publikováno v: Human Mutation
Gallon, R, Sheth, H, Hayes, C, Redford, L, Alhilal, G, O’Brien, O, Spiewak, H, Waltham, A, McAnulty, C, Izuogu, O, Arends, M, Oniscu, A, Miguel Alonso, Á, Moreno Laguna, S, Borthwick, G, Santibanez Koref, M, Jackson, M S & Burn, J 2019, ' Sequencing-based microsatellite instability testing using as few as six markers for high throughput clinical diagnostics ', Human Mutation . https://doi.org/10.1002/humu.23906

Microsatellite instability (MSI) testing of colorectal cancers (CRCs) is used to screen for Lynch syndrome (LS), a hereditary cancer‐predisposition, and can be used to predict response to immunotherapy. Here, we present a single‐molecule molecula

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dcf7107f845710b3b720be0ba8b2b221
https://doi.org/10.1002/humu.23906