Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Amanda Tallon"'
Electrophilic small molecules that can reversibly modify proteins are of growing interest in drug discovery. However, the ability to study reversible covalent probes in live cells can be limited by their reversible reactivity after cell lysis and in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bf684902025e2264e40dcc5eea4c9189
https://doi.org/10.26434/chemrxiv-2023-w0p5m
https://doi.org/10.26434/chemrxiv-2023-w0p5m
α-Chiral Amines via Thermally Promoted Deaminative Addition of Alkylpyridinium Salts to Sulfinimines
Autor:
Mary P. Watson, Amanda Tallon, Kristen M. Baker, Matthew A. Perry, Olivia P. Bercher, Richard P. Loach
Publikováno v:
Org Lett
A deaminative reaction of Katritzky alkylpyridinium salts and sulfinimines has been developed to deliver enantiopure α-chiral amines. The success of this method relied on the discovery of a thermally promoted deamination via single-electron transfer
Publikováno v:
Angew Chem Int Ed Engl
As tetrazines are important tools to the field of bioorthogonal chemistry, there is a need for new approaches to synthesize unsymmetrical and 3-monosubstituted tetrazines. Described here is a general, one-pot method for converting (3methyloxetan-3-yl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7df9a04121ccef055122d779cb9ed293
https://doi.org/10.26434/chemrxiv.12141189.v1
https://doi.org/10.26434/chemrxiv.12141189.v1