Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Amanda Sheets"'
Autor:
Sandra McCurdy, Ashley Nenninger, Amanda Sheets, Kara Keedy, Laura Lawrence, Megan Quintas, Sue Cammarata
Publikováno v:
International Journal of Infectious Diseases, Vol 97, Iss , Pp 374-379 (2020)
Objectives: To report atypical pathogens from clinical trial data comparing delafloxacin to moxifloxacin in the treatment of adults with community-acquired bacterial pneumonia (CABP). Methods: Multiple diagnostic methods were employed to diagnose aty
Externí odkaz:
https://doaj.org/article/8753cdbf01a943f1b490eb3d22e34b28
Autor:
Megan Quintas, Sandra P. McCurdy, Amanda Sheets, Kara Keedy, Laura Lawrence, Sue Cammarata, Ashley Nenninger
Publikováno v:
International Journal of Infectious Diseases, Vol 97, Iss, Pp 374-379 (2020)
Objectives To report atypical pathogens from clinical trial data comparing delafloxacin to moxifloxacin in the treatment of adults with community-acquired bacterial pneumonia (CABP). Methods Multiple diagnostic methods were employed to diagnose atypi
Autor:
Megan Quintas, Sandra P. McCurdy, Amanda Sheets, Kara Keedy, Sue Cammarata, Laura Lawrence, Ashley Nenninger
Publikováno v:
Antimicrobial Agents and Chemotherapy
Delafloxacin is a novel fluoroquinolone with activity against Gram-positive, Gram-negative, and atypical pathogens, including fluoroquinolone-nonsusceptible methicillin-resistant Staphylococcus aureus (MRSA). The microbiological results of a phase 3
Autor:
Dirkie Johanna Van Rensburg, Prabhavathi Fernandes, Carlos Barrera, Anita Das, Ismail Mitha, Pablo Alexis Doreski, Kay Clark, Kara Keedy, Jose Flores-Figueroa, Barbara Rewerska, Brian D. Jamieson, Amanda Sheets, David Oldach, Najumuddin Karimjee, Hristo Metev, Yuri Antonovsky, Joseph McDermott Molina, Cristina Mihaela Tanaseanu, Gary Horwith, Analia Mykietiuk, Mimi Floarea Nitu, Brian H. Rowe, Drusilla Scott
Publikováno v:
The Lancet Infectious Diseases. 16:421-430
Summary Background Community-acquired bacterial pneumonia (CABP) is a leading cause of morbidity and mortality, and treatment recommendations, each with specific limitations, vary globally. We aimed to compare the efficacy and safety of solithromycin
Autor:
Megan Quintas, Ashley Nenninger, Amanda Sheets, Sandra P. McCurdy, Sue Cammarata, Kara Keedy, Laura Lawrence, Yang Li
Publikováno v:
Chest. 156:A422-A423
Publikováno v:
Open Forum Infectious Diseases
Background DLX is a novel fluoroquinolone (FQ) antibiotic with Gram-positive/MRSA, Gram-negative and atypical activity. It offers IV and oral treatment with no QT restrictions. In a Phase 3 study in CABP patients, DLX was non-inferior to moxifloxacin
Publikováno v:
Open Forum Infectious Diseases
Background Fusidic acid (FA) is an anti-staphylococcal agent used to treat chronic bone and joint infections (BJI) due to the availability of an oral formulation and its MRSA activity. Though used widely throughout the world for decades, FA is not ap
Autor:
Joven Gonong, Brian D. Jamieson, Thomas M. File, David N. Taylor, Violeta Vucinic-Mihailovic, Prabhavathi Fernandes, Barbara Rewerska, Anita Das, Amanda Sheets, David Oldach, Kara Keedy
Publikováno v:
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 63(8)
Background Solithromycin, a novel macrolide antibiotic with both intravenous and oral formulations dosed once daily, has completed 2 global phase 3 trials for treatment of community-acquired bacterial pneumonia. Methods A total of 863 adults with com
Autor:
Carol S. Inatsuka, Michael W. Henderson, Corinne L. Williams, David J. Benaron, Erik L. Hewlett, Mary C. Gray, Gina M. Donato, Peggy A. Cotter, Amanda Sheets
Publikováno v:
Infection and Immunity. 80:2061-2075
Bordetella pertussis and Bordetella bronchiseptica establish respiratory infections with notorious efficiency. Our previous studies showed that the fhaB genes of B. pertussis and B. bronchiseptica , which encode filamentous hemagglutinin (FHA), are f
Autor:
Joseph W. St. Geme, Amanda Sheets
Publikováno v:
Journal of Bacteriology. 193:329-339
The Haemophilus cryptic genospecies is an important cause of maternal genital tract and neonatal systemic infections and initiates infection by colonizing the genital or respiratory epithelium. In recent work, we identified a unique Haemophilus crypt