Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Amanda Scherer"'
Autor:
Qierra R. Brockman, Amanda Scherer, Gavin R. McGivney, Wade R. Gutierrez, Jeffrey Rytlewski, Alexa Sheehan, Akshaya Warrier, Emily A. Laverty, Grace Roughton, Nina C. Carnevale, Vickie Knepper-Adrian, Rebecca D. Dodd
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract CRISPR/Cas9 gene editing has evolved from a simple laboratory tool to a powerful method of in vivo genomic engineering. As the applications of CRISPR/Cas9 technology have grown, the need to characterize the breadth and depth of indels genera
Externí odkaz:
https://doaj.org/article/36c28b8809a147058959426b72e59f6f
Autor:
Wade R. Gutierrez, Jeffrey D. Rytlewski, Amanda Scherer, Grace A. Roughton, Nina C. Carnevale, Krisha Y. Vyas, Gavin R. McGivney, Qierra R. Brockman, Vickie Knepper-Adrian, Rebecca D. Dodd
Publikováno v:
Current Issues in Molecular Biology, Vol 45, Iss 2, Pp 1218-1232 (2023)
Rhabdomyosarcoma (RMS) is an aggressive form of cancer that accounts for half of all pediatric soft tissue sarcomas. Little progress has been made in improving survival outcomes over the past three decades. Mouse models of rhabdomyosarcoma are a crit
Externí odkaz:
https://doaj.org/article/aadfd4285500410b8d0e896539fe86c7
Autor:
Wade R. Gutierrez, Amanda Scherer, Jeffrey D. Rytlewski, Emily A. Laverty, Alexa P. Sheehan, Gavin R. McGivney, Qierra R. Brockman, Vickie Knepper-Adrian, Grace A. Roughton, Dawn E. Quelle, David J. Gordon, Varun Monga, Rebecca D. Dodd
Publikováno v:
JCI Insight, Vol 7, Iss 22 (2022)
The DNA methyltransferase inhibitor decitabine has classically been used to reactivate silenced genes and as a pretreatment for anticancer therapies. In a variation of this idea, this study explores the concept of adding low-dose decitabine (DAC) fol
Externí odkaz:
https://doaj.org/article/f1f2ba4470e1443796a237d00e963599
Autor:
Qierra R. Brockman, Amanda Scherer, Gavin R. McGivney, Wade R. Gutierrez, Andrew P. Voigt, Alexandra L. Isaacson, Emily A. Laverty, Grace Roughton, Vickie Knepper-Adrian, Benjamin Darbro, Munir R. Tanas, Christopher S. Stipp, Rebecca D. Dodd
Publikováno v:
JCI Insight, Vol 7, Iss 20 (2022)
The histone methyltransferase PRC2 plays a complex role in cancer. Malignant peripheral nerve sheath tumors (MPNSTs) are aggressive sarcomas with frequent loss-of-function mutations in PRC2 that are associated with poor outcome. Here, we identify a c
Externí odkaz:
https://doaj.org/article/72aae0cfd35e4271a50d462f47391a87
Autor:
Wade R. Gutierrez, Amanda Scherer, Gavin R. McGivney, Qierra R. Brockman, Vickie Knepper-Adrian, Emily A. Laverty, Grace A. Roughton, Rebecca D. Dodd
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Immune cells play critical functions in cancer, and mice with intact immune systems are vital to understanding tumor immunology. Both genetically engineered mouse models (GEMMs) and syngeneic cell transplant approaches use immunocompetent mi
Externí odkaz:
https://doaj.org/article/8c80128f3ad64d2eaaee4e5ea0d6de23
Publikováno v:
Signo y Seña, Vol 0, Iss 24, Pp 21-34 (2016)
Este artigo objetiva a compreensão da constituição disciplinar contemporânea, explicitando os modos de nomear e designar uma disciplina no espaço institucional. Trata-se do caso especifico da Análise de Discurso nos Programas de Pós-Graduaçã
Externí odkaz:
https://doaj.org/article/60496a23fe0a4a28aa750d0f0d80f9ae
Autor:
Amanda Scherer, Spencer Kuhl, Deborah Wessels, Daniel F Lusche, Brett Hanson, Joseph Ambrose, Edward Voss, Emily Fletcher, Charles Goldman, David R Soll
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0118628 (2015)
We have developed a 4D computer-assisted reconstruction and motion analysis system, J3D-DIAS 4.1, and applied it to the reconstruction and motion analysis of tumorigenic cells in a 3D matrix. The system is unique in that it is fast, high-resolution,
Externí odkaz:
https://doaj.org/article/291e48cb433140c2b091b710160c2dbf
Autor:
David G. Kirsch, Ashutosh Chilkoti, William C. Eward, Diana M. Cardona, Eric M. Mastria, Yan Ma, Mark Chen, Warren Floyd, Vickie Knepper-Adrian, Soumen Saha, Parisa Yousefpour, Victoria R. Stephens, Kathleen A. Ashcraft, Emily A. Laverty, Wade R. Gutierrez, Gavin R. McGivney, Wesley Huang, Amanda Scherer, Rebecca D. Dodd
Purpose:Nanoparticle-encapsulated drug formulations can improve responses to conventional chemotherapy by increasing drug retention within the tumor and by promoting a more effective antitumor immune response than free drug. New drug delivery modalit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b4ef0d49969e1326a047182705f3490
https://doi.org/10.1158/1078-0432.c.6529004
https://doi.org/10.1158/1078-0432.c.6529004
Autor:
David G. Kirsch, Ashutosh Chilkoti, William C. Eward, Diana M. Cardona, Eric M. Mastria, Yan Ma, Mark Chen, Warren Floyd, Vickie Knepper-Adrian, Soumen Saha, Parisa Yousefpour, Victoria R. Stephens, Kathleen A. Ashcraft, Emily A. Laverty, Wade R. Gutierrez, Gavin R. McGivney, Wesley Huang, Amanda Scherer, Rebecca D. Dodd
Supplementary Figures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b718e8b90fbefc5054afdf86244901d6
https://doi.org/10.1158/1078-0432.22475132.v1
https://doi.org/10.1158/1078-0432.22475132.v1
Autor:
Amanda Scherer, Emily A. Laverty, David G. Kirsch, Victoria R. Stephens, William C. Eward, Ashutosh Chilkoti, Eric M. Mastria, Gavin R. McGivney, Warren Floyd, Soumen Saha, Kathleen A. Ashcraft, Parisa Yousefpour, Rebecca D. Dodd, Wade R. Gutierrez, Wesley Huang, Yan Ma, Mark Chen, Diana M. Cardona, Vickie Knepper-Adrian
Publikováno v:
Clin Cancer Res
Purpose: Nanoparticle-encapsulated drug formulations can improve responses to conventional chemotherapy by increasing drug retention within the tumor and by promoting a more effective antitumor immune response than free drug. New drug delivery modali
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c485de789b18189ee02b81a67028d0c
https://doi.org/10.1158/1078-0432.ccr-19-2597
https://doi.org/10.1158/1078-0432.ccr-19-2597