Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Amanda S. Gentilello"'
Autor:
Masashi Takahashi, Ahmed Z. Balboula, Karen Schindler, Amanda S. Gentilello, Cecilia S. Blengini
Publikováno v:
Biology of Reproduction. 96:1197-1209
During oocyte meiotic maturation, Aurora kinase C (AURKC) is required to accomplish many critical functions including destabilizing erroneous kinetochore–microtubule (K-MT)attachments and regulating bipolar spindle assembly. How localized activity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c5fc6020dccb64ab1bcbc3b3968c415
https://doi.org/10.1093/biolre/iox047
https://doi.org/10.1093/biolre/iox047
Autor:
Marcos Malumbres, Alexandra L. Nguyen, Berta N. Vazquez, Karen Schindler, David Drutovic, Warif El Yakoubi, Amanda S. Gentilello, Petr Solc
SUMMARY: Errors in chromosome segregation during female meiosis I occur frequently, and aneuploid embryos account for 1/3 of all miscarriages in humans [1]. Unlike mitotic cells that require two Aurora kinase (AURK) homologs to help prevent aneuploid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99ae8eb961cb0d518e046c7e9fd12491
https://europepmc.org/articles/PMC6234855/
https://europepmc.org/articles/PMC6234855/
Autor:
Alexandra L. Nguyen, Karen Schindler, David Drutovic, Ahmed Z. Balboula, Petr Solc, Amanda S. Gentilello, Suzanne M. Quartuccio
Publikováno v:
Journal of Cell Science.
Meiotic oocytes lack classic centrosomes and therefore, bipolar spindle assembly depends on clustering of acentriolar microtubule-organizing centers (MTOCs) into two poles. However, the molecular mechanism regulating MTOCs assembly into two poles is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc3ca29273ecf473647df5e7d4fe1179
https://doi.org/10.1242/jcs.189340
https://doi.org/10.1242/jcs.189340
Autor:
Jacob Ohring, Karen Schindler, Ahmed Z. Balboula, Alexandra L. Nguyen, Amanda S. Gentilello, Vibha Shrivastava
Publikováno v:
Journal of Cell Science.
Meiosis I (MI), the division that generates haploids, is prone to errors that lead to aneuploidy in females. Haspin is a kinase that phosphorylates histone H3 on threonine 3, thereby recruiting Aurora kinase B (AURKB) and the chromosomal passenger co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcbef20e8b416640eb947a12f1f84863
https://doi.org/10.1242/jcs.158840
https://doi.org/10.1242/jcs.158840