Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Amanda S, Machado"'
Autor:
Fernanda F. Ramos, Flávia F. Bagno, Paula F. Vassallo, João A. Oliveira-da-Silva, Thiago A. R. Reis, Raquel S. Bandeira, Amanda S. Machado, Daniela P. Lage, Vivian T. Martins, Ana P. Fernandes, Myron Christodoulides, Cecilia G. Ravetti, Vandack Nobre, Flávio G. da Fonseca, Eduardo A. F. Coelho, Fernanda Ludolf
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Serological assays have been widely used to detect anti-SARS-CoV-2 antibodies, which are generated from previous exposure to the virus or after vaccination. The presence of anti-SARS-CoV-2 Nucleocapsid antibodies was recently reported in pat
Externí odkaz:
https://doaj.org/article/9aeb16b80f8f40768e7585e07a9d9e5f
Autor:
Danniele L. Vale, Camila S. Freitas, Vívian T. Martins, Gabriel J. L. Moreira, Amanda S. Machado, Fernanda F. Ramos, Isabela A. G. Pereira, Raquel S. Bandeira, Marcelo M. de Jesus, Grasiele S. V. Tavares, Fernanda Ludolf, Miguel A. Chávez-Fumagalli, Alexsandro S. Galdino, Ricardo T. Fujiwara, Lílian L. Bueno, Bruno M. Roatt, Myron Christodoulides, Eduardo A. F. Coelho, Daniela P. Lage
Publikováno v:
Biology, Vol 12, Iss 6, p 851 (2023)
Visceral leishmaniasis (VL) in the Americas is a chronic systemic disease caused by infection with Leishmania infantum parasites. The toxicity of antileishmanial drugs, long treatment course and limited efficacy are significant concerns that hamper a
Externí odkaz:
https://doaj.org/article/02ab76904ab1425b9580143214a0b6b9
Autor:
Tauane G. Soyer, Fernanda F. Ramos, Isabela A. G. Pereira, Daniela P. Lage, Raquel S. Bandeira, Marcelo M. de Jesus, Guilherme P. Costa, Amanda S. Machado, Camila S. Freitas, Danniele L. Vale, Vívian T. Martins, Alexsandro S. Galdino, Miguel A. Chávez-Fumagalli, Daniel Menezes-Souza, Mariana C. Duarte, Bruno M. Roatt, Eduardo A. F. Coelho, Grasiele S. V. Tavares
Publikováno v:
Pathogens, Vol 12, Iss 2, p 314 (2023)
Leishmania amazonensis can cause cutaneous and visceral clinical manifestations of leishmaniasis in infected hosts. Once the treatment against disease is toxic, presents high cost, and/or there is the emergence of parasite-resistant strains, alternat
Externí odkaz:
https://doaj.org/article/0e72ffa459d24221bdbdd07350467a1d
Autor:
Daniela P. Lage, Danniele L. Vale, Flávia P. Linhares, Camila S. Freitas, Amanda S. Machado, Jamille M. O. Cardoso, Daysiane de Oliveira, Nathália C. Galvani, Marcelo P. de Oliveira, João A. Oliveira-da-Silva, Fernanda F. Ramos, Grasiele S. V. Tavares, Fernanda Ludolf, Raquel S. Bandeira, Isabela A. G. Pereira, Miguel A. Chávez-Fumagalli, Bruno M. Roatt, Ricardo A. Machado-de-Ávila, Myron Christodoulides, Eduardo A. F. Coelho, Vívian T. Martins
Publikováno v:
Vaccines, Vol 10, Iss 7, p 1146 (2022)
Currently, there is no licensed vaccine to protect against human visceral leishmaniasis (VL), a potentially fatal disease caused by infection with Leishmania parasites. In the current study, a recombinant chimeric protein ChimT was developed based on
Externí odkaz:
https://doaj.org/article/73eb6f48a1ba4ae29ec937b48a427241
Autor:
Daniela P. Lage, Amanda S. Machado, Camila S. Freitas, Danniele L. Vale, Flávia P. Linhares, Jamille M.O. Cardoso, João A. Oliveira-da-Silva, Fernanda F. Ramos, Isabela A.G. Pereira, Fernanda Ludolf, Grasiele S.V. Tavares, Raquel S. Bandeira, Jamil S. Oliveira, Daniel Menezes-Souza, Mariana C. Duarte, Alexsandro S. Galdino, Myron Christodoulides, Miguel A. Chávez-Fumagalli, Bruno M. Roatt, Vívian T. Martins, Eduardo A.F. Coelho
Publikováno v:
Molecular Immunology. 155:79-90
Autor:
Lage, Danniele L. Vale, Camila S. Freitas, Vívian T. Martins, Gabriel J. L. Moreira, Amanda S. Machado, Fernanda F. Ramos, Isabela A. G. Pereira, Raquel S. Bandeira, Marcelo M. de Jesus, Grasiele S. V. Tavares, Fernanda Ludolf, Miguel A. Chávez-Fumagalli, Alexsandro S. Galdino, Ricardo T. Fujiwara, Lílian L. Bueno, Bruno M. Roatt, Myron Christodoulides, Eduardo A. F. Coelho, Daniela P.
Publikováno v:
Biology; Volume 12; Issue 6; Pages: 851
Visceral leishmaniasis (VL) in the Americas is a chronic systemic disease caused by infection with Leishmania infantum parasites. The toxicity of antileishmanial drugs, long treatment course and limited efficacy are significant concerns that hamper a
Autor:
Daniela P. Lage, Patrícia A.F. Ribeiro, Daniel S. Dias, Débora V.C. Mendonça, Fernanda F. Ramos, Lívia M. Carvalho, Bethina T. Steiner, Grasiele S.V. Tavares, Vívian T. Martins, Amanda S. Machado, João A. Oliveira-da-Silva, Thaís T.O. Santos, Camila S. Freitas, Jamil S. Oliveira, Bruno M. Roatt, Ricardo A. Machado-de-Ávila, Maria V. Humbert, Myron Christodoulides, Eduardo A.F. Coelho
Publikováno v:
Vaccines, Vol 8, Iss 2, p 289 (2020)
Background: Leishmaniases are neglected diseases caused by infection with Leishmania parasites and there are no human vaccines in use routinely. The purpose of this study was to examine the immunogenicity of ChimeraT, a novel synthetic recombinant va
Externí odkaz:
https://doaj.org/article/0d348c69932349ab9c3924f3d9114030
Autor:
Amanda S. Machado, Ricardo Andrez Machado-de-Ávila, Grasiele S.V. Tavares, Vívian T. Martins, Daniela P. Lage, Camila S. Freitas, Débora V.C. Mendonça, João A. Oliveira-da-Silva, Myron Christodoulides, Gláucia Fernandes Cota, Unaí Tupinambás, Fernanda Ludolf, Thiago A.R. Reis, Nathalia Sernizon Guimarães, Danniele L. Vale, Fernanda F. Ramos, Eduardo A.F. Coelho, Gabriel Paulino Luiz, Daysiane de Oliveira, Nathália C. Galvani, Ana Thereza Chaves, Maria Victoria Humbert, Bruna B. Fernandes
Publikováno v:
Parasitology Research
Visceral leishmaniasis (VL) is a neglected tropical disease of global importance caused by parasites of the genus Leishmania, and coinfection with human immunodeficiency virus (HIV) is common in countries where both diseases are endemic. In particula
Autor:
Daniela P. Lage, Rafaella R Costa, Gabriela Silva Ramos, João A. Oliveira-da-Silva, Débora V.C. Mendonça, Rodrigo Maia de Pádua, Bruno Mendes Roatt, Rory Cristiane Fortes de Brito, Fernanda F. Ramos, Priscilla R. V. Campana, Fernão Castro Braga, Camila S. Freitas, Amanda S. Machado, Fernanda Ludolf, Luciana M.R. Antinarelli, Flaviano Melo Ottoni, Miguel A. Chávez-Fumagalli, Elaine Soares Coimbra, Thiago A.R. Reis, Vinicio T.S. Coelho, Maria Victoria Humbert, Jennifer Munkert, Vívian T. Martins, Grasiele S.V. Tavares, Eduardo A.F. Coelho
Publikováno v:
Parasitology Research
Treatment for visceral leishmaniasis (VL) is hampered mainly by drug toxicity, their high cost, and parasite resistance. Drug development is a long and pricey process, and therefore, drug repositioning may be an alternative worth pursuing. Cardenolid
Autor:
Jamil S. Oliveira, Myron Christodoulides, Ricardo Andrez Machado-de-Ávila, Patrícia A.F. Ribeiro, Lívia M. Carvalho, Bethina T. Steiner, Vívian T. Martins, Grasiele S.V. Tavares, Daysiane de Oliveira, Luísa Perin, Thaís T.O. Santos, Fernanda F. Ramos, Eduardo A.F. Coelho, Daniel Dias, Débora V.C. Mendonça, Bruno Mendes Roatt, Daniela P. Lage, Antônio Lúcio Teixeira, Amanda S. Machado, Maria Victoria Humbert, João A. Oliveira-da-Silva
Publikováno v:
npj Vaccines, Vol 5, Iss 1, Pp 1-13 (2020)
Leishmaniases are neglected diseases caused by infection with Leishmania parasites and there are currently no prophylactic vaccines. In this study, we designed in silico a synthetic recombinant vaccine against visceral leishmaniasis (VL) called Chime