Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Amanda Redfern"'
Publikováno v:
Journal of Surgical Education. 78:342-345
Background Downloadable audio files called podcasts have become popular within many areas of medical education. They can be a valuable supplement to traditional teaching methods. Medical educators may wish to incorporate podcasts into their curriculu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e0dfcf8331dd0ddc04fc90fb842e213
https://doi.org/10.1016/j.jsurg.2020.06.041
https://doi.org/10.1016/j.jsurg.2020.06.041
Autor:
Barbara Vollmayr, Luca Marchetti, Mario Lauria, Lucia Carboni, Amanda Redfern, Maria Razzoli, Aleksander A. Mathé, Karim Malki, Enrico Domenici, Lesley Jones, Peter Gass, Marco A. Riva, Veronica Begni, Laura Caberlotto
An enhanced understanding of the pathophysiology of depression would facilitate the discovery of new efficacious medications. To this end, we examined hippocampal transcriptional changes in rat models of disease and in humans to identify common disea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a613b609b3404b6171ca748543b621a
http://hdl.handle.net/11585/658652
http://hdl.handle.net/11585/658652
Autor:
A. Jennifer Morton, Stephen B. Dunnett, Amanda Redfern, Lesley Jones, Paul D. Lewis, Angela Hodges, Mark J. Hunt
Publikováno v:
European Journal of Neuroscience. 21:855-870
Huntington's disease is a genetic disease caused by a single mutation. It is characterized by progressive movement, emotional and cognitive deficits. R6/2 mice transgenic for exon 1 of the HD gene with 150+ CAG repeats have a progressive neurological
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::87c55285a9a94b9af907dcd8ccf4aba2
https://doi.org/10.1111/j.1460-9568.2005.03895.x
https://doi.org/10.1111/j.1460-9568.2005.03895.x
Publikováno v:
Prostaglandins, Leukotrienes and Essential Fatty Acids (PLEFA). 62:119-127
Gamma linolenic acid (GLA) is a polyunsaturated fatty acid, which induces cytotoxicity and regulates cell adhesion in cancer cells. The molecular mechanism of these actions is not clear. We have shown that GLA acts via peroxisome proliferator activat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96f1a977db2399003111411eb5204289
https://doi.org/10.1054/plef.1999.0131
https://doi.org/10.1054/plef.1999.0131
Autor:
Lesley Jones, Sophie Aubert, Nicole Déglon, Aurore Bugi, Peter Giles, Marta Ruiz, Fany Bourgois-Rocha, Anselme L. Perrier, Nathalie Lefort, Nicholas D. Allen, Marc Peschanski, Amanda Redfern, Caroline Bonnefond, Maxime Feyeux
Publikováno v:
Human molecular genetics. 21(17)
Huntington's disease (HD) is characterized by a late clinical onset despite ubiquitous expression of the mutant gene at all developmental stages. How mutant huntingtin impacts on signalling pathways in the pre-symptomatic period has remained essentia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d771fe5cd0c04b137d33df72d4470da2
https://pubmed.ncbi.nlm.nih.gov/22678061
https://pubmed.ncbi.nlm.nih.gov/22678061
Autor:
Erin Watkin, Jian Hong Li, Guo Li Ming, Marco Onorati, Ranjit Singh Atwal, James A. Thomson, Vanessa C. Wheeler, Robert N. Cole, Amanda R. Mason, Woon Roung Kim, Nicholas D. Allen, Tammy Gillis, Gayani Batugedara, Allison D. Ebert, Yu Zhu, Alvin R. King, Jason H. Chiang, Peter J. Donovan, Julia A. Kaye, Jamshid Arjomand, Christopher A. Ross, Junying Yu, Marquis P. Vawter, Sara T. Winokur, Amanda Redfern, Sergey S Akimov, Georgia Makri, Stephen P. Brazier, Alysia Battersby, Xiaoli Chen, Valentina Castiglioni, Aaron C. Daub, Punita Sharma, Elisa Fossale, Clive N. Svendsen, Ihn Sik Seong, James F. Gusella, Malcolm Casale, Tamara Ratovitski, Paul J. Kemp, Nicolas Arbez, Hongjun Song, Elena Cattaneo, Leslie M. Thompson, Jayalakshmi S. Mysore, Virginia B. Mattis, Leslie F. Lock, Russell L. Margolis, Soshana P. Svendsen, David Rushton, Yiping Shen, Chun Zhong, Steven Finkbeiner, Tarja A. Juopperi, Marcy E. MacDonald, Hsui Er Tseng, Alexander William John Harrison, Eka Chighladze
Publikováno v:
Cell stem cell. 11(2)
SummaryHuntington's disease (HD) is an inherited neurodegenerative disorder caused by an expanded stretch of CAG trinucleotide repeats that results in neuronal dysfunction and death. Here, The HD Consortium reports the generation and characterization
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::220351e85ee7daa05622d72e75cf00ea
https://pubmed.ncbi.nlm.nih.gov/22748968
https://pubmed.ncbi.nlm.nih.gov/22748968
Publikováno v:
Cancer Metastasis, Molecular and Cellular Mechanisms and Clinical Intervention ISBN: 0792363957
Highly unsaturated fatty acids (HUFAs) have been demonstrated to have anticancer functions in the past decade. Recently, these fatty acids have been shown to exert a regulatory action on tumour cell motility, invasion and metastatic behaviour via suc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::58f1c1b97e6ff9f6e197248ce82bcc8f
https://doi.org/10.1007/0-306-48388-2_9
https://doi.org/10.1007/0-306-48388-2_9
Autor:
Peter J. Donovan, Julia A. Kaye, Guo Li Ming, Yiping Shen, Tammy Gillis, Steven Finkbeiner, Tarja A. Juopperi, Y Zhu, James A. Thomson, Allison D. Ebert, E Chighladze, J-h Li, Amanda R. Mason, Christopher A. Ross, Paul J. Kemp, Junying Yu, JH Chiang, Stephen P. Brazier, Alexander William John Harrison, Ranjit Singh Atwal, Ihn Sik Seong, Valentina Castiglioni, Chun Zhong, James F. Gusella, Leslie F. Lock, Elena Cattaneo, Nicolas Arbez, H-E Tseng, RN Cole, WR Kim, Marquis P. Vawter, Elisa Fossale, Hongjun Song, Gayani Batugedara, Georgia Makri, Tamara Ratovitski, Clive N. Svendsen, Alysia Battersby, Virginia B. Mattis, E Watkin, Malcolm Casale, Ar King, Aaron C. Daub, Punita Sharma, Amanda Redfern, Jayalakshmi S. Mysore, Leslie M. Thompson, Russell L. Margolis, Soshana P. Svendsen, David Rushton, Sergey S Akimov, Marco Onorati, Nicholas D. Allen, Vanessa C. Wheeler, Marcy E. MacDonald, Jamshid Arjomand, Sara T. Winokur, X Chen
Publikováno v:
Journal of Neurology, Neurosurgery & Psychiatry. 83:A3.2-A4
Background The expression of mutant HTT leads to many cellular alterations, including abnormal vesicle recycling, loss of signalling by brain-derived neurotrophic factor, excitotoxicity, perturbation of Ca 2+ signalling, decreases in intracellular AT
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cc83aaf4fe0cb7630cafcdd3d79831f9
https://doi.org/10.1136/jnnp-2012-303524.11
https://doi.org/10.1136/jnnp-2012-303524.11
Publikováno v:
Biochemical Society Transactions. 22:308S-308S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29eadba147591061ccdda21142d93650
https://doi.org/10.1042/bst022308s
https://doi.org/10.1042/bst022308s