Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Amanda R. Weyerbacher"'
Publikováno v:
Pain. 148:237-246
Following peripheral inflammation, NMDA receptor (NMDAR) activation in spinal cord dorsal horn neurons facilitates the generation of pain in response to low threshold inputs (allodynia) and signals the phosphorylation of protein kinase C (pPKC) and e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2caf33a64e7b1204b8b8efee8f1657a
https://doi.org/10.1016/j.pain.2009.11.003
https://doi.org/10.1016/j.pain.2009.11.003
Publikováno v:
The Journal of Neuroscience. 28:14087-14096
Extracellular signal-regulated kinase 1 (ERK1) and ERK2 signaling in the spinal cord dorsal horn (SCDH) has been implicated in injury-induced pain hypersensitivity. Available ERK pathway inhibitors cannot distinguish between ERK1 and ERK2, nor can th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::463db10725ce82a5e4ad22c5ad540c9f
https://doi.org/10.1523/jneurosci.2406-08.2008
https://doi.org/10.1523/jneurosci.2406-08.2008
Autor:
Hsinlin T Cheng, Qinghao Xu, Megumi Ohata, Samantha M. South, Masahiro Suzuki, Deborah M. Hegarty, Amanda R. Weyerbacher, Charles E. Inturrisi
Publikováno v:
Neuroscience. 155:948-958
The N-methyl-d-aspartate (NMDA) receptor in the spinal cord dorsal horn (SCDH) is one of the mechanisms involved in central sensitization during chronic pain. Previously, this laboratory created a spatio-temporal knockout (KO) of the N-methyl-d-aspar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37bd13631be14a392398d6af7b39932b
https://doi.org/10.1016/j.neuroscience.2008.06.024
https://doi.org/10.1016/j.neuroscience.2008.06.024
Autor:
Baruch Brenner, Gary K. Schwartz, Marija Drobnjak, Mithat Gonen, Monica Motwani, David P. Kelsen, Sandy Yi, Carlos Cordon-Cardo, Jeremy S. Kortmansky, William P. Tong, Leonard B. Saltz, Manish A. Shah, Amanda R. Weyerbacher, Eileen M. O'Reilly, Robert A. Lefkowitz
Publikováno v:
Clinical Cancer Research. 11:3836-3845
Purpose: Flavopiridol potently enhances the effect of irinotecan with cures in colorectal cancer xenografts, and is associated with modulation of several molecular targets, including p21, Differentiation-related gene 1 (Drg1), and p53. We initiated a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ed992240b0c2cfe02be10be98ef71eb
https://doi.org/10.1158/1078-0432.ccr-04-2651
https://doi.org/10.1158/1078-0432.ccr-04-2651
Autor:
Manish A. Shah, Robert G. Maki, David P. Kelsen, Sandy Yi, Amanda R. Weyerbacher, Jeremy S. Kortmansky, Leonard B. Saltz, Gary K. Schwartz, William P. Tong, Eileen M. O'Reilly, Nancy E. Kemeny, D. Ilson, Andreas Kaubisch, Mithat Gonen, Rebecca Sowers
Publikováno v:
Journal of Clinical Oncology. 23:1875-1884
Purpose Preclinical studies indicate that the cyclin-dependent kinase and protein kinase C inhibitor 7-hydroxystaurosporine (UCN-01) potentiates the cytotoxic effects of fluorouracil (FU). We designed a phase I clinical trial of FU in combination wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::142974f98246b703df67757550b002c2
https://doi.org/10.1200/jco.2005.03.116
https://doi.org/10.1200/jco.2005.03.116
Publikováno v:
The Journal of Pain. 10:S28
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aa26a63bc6a411f97fdf1b7e9b723952
https://doi.org/10.1016/j.jpain.2009.01.120
https://doi.org/10.1016/j.jpain.2009.01.120
Publikováno v:
The Journal of Pain. 9:10
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::91683836f2ebae00892a5ea67e49cb03
https://doi.org/10.1016/j.jpain.2008.01.056
https://doi.org/10.1016/j.jpain.2008.01.056
Autor:
Eugenie Obbens, Natalie Moryl, Dana Tarcatu, Charles E. Inturrisi, A. Faskowitz, Amanda R. Weyerbacher, M. Jahdi, Cristina Tamasdan
Publikováno v:
The Journal of Pain. 9:24
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::874bd3ae69c9a0b2390f5c7356e2f143
https://doi.org/10.1016/j.jpain.2008.01.115
https://doi.org/10.1016/j.jpain.2008.01.115