Zobrazeno 1 - 10
of 88
pro vyhledávání: '"Amanda R. Wasylishen"'
Autor:
Chenran Wang, Aarti Nagayach, Harsh Patel, Lan Dao, Hui Zhu, Amanda R. Wasylishen, Yanbo Fan, Ady Kendler, Ziyuan Guo
Publikováno v:
Breast Cancer Research, Vol 26, Iss 1, Pp 1-16 (2024)
Abstract Background Metastasis, the spread, and growth of malignant cells at secondary sites within a patient’s body, accounts for over 90% of cancer-related mortality. Breast cancer is the most common tumor type diagnosed and the leading cause of
Externí odkaz:
https://doaj.org/article/0aeee57c93ca40d9be2c8e2f14adcb42
Autor:
Chang Sun, Yuan Qi, Natalie Fowlkes, Nina Lazic, Xiaoping Su, Guillermina Lozano, Amanda R. Wasylishen
Publikováno v:
Cell Death and Disease, Vol 14, Iss 8, Pp 1-9 (2023)
Abstract Daxx functions as a histone chaperone for the histone H3 variant, H3.3, and is essential for embryonic development. Daxx interacts with Atrx to form a protein complex that deposits H3.3 into heterochromatic regions of the genome, including c
Externí odkaz:
https://doaj.org/article/a2b8e003959247d18bd59dc80dcac901
Autor:
Chang Sun, Jeannelyn S. Estrella, Elizabeth M. Whitley, Gilda P. Chau, Guillermina Lozano, Amanda R. Wasylishen
Publikováno v:
Disease Models & Mechanisms, Vol 15, Iss 8 (2022)
Genome sequencing has revealed the importance of epigenetic regulators in tumorigenesis. The genes encoding the chromatin remodeling complex DAXX:ATRX are frequently mutated in pancreatic neuroendocrine tumors; however, the underlying mechanisms of h
Externí odkaz:
https://doaj.org/article/1d796c1cc30249a89d86ee96573ada87
Autor:
Marc El Beaino, Jiayong Liu, Amanda R. Wasylishen, Rasoul Pourebrahim, Agata Migut, Bryan J. Bessellieu, Ke Huang, Patrick P. Lin
Publikováno v:
BMC Cancer, Vol 20, Iss 1, Pp 1-14 (2020)
Abstract Background Ewing sarcoma is a malignancy of primitive cells, possibly of mesenchymal origin. It is probable that genetic perturbations other than EWS-FLI1 cooperate with it to produce the tumor. Sequencing studies identified STAG2 mutations
Externí odkaz:
https://doaj.org/article/5d2b73d0991a4547b65880f1593634a9
Autor:
Crystal Tonnessen-Murray, Nathan A. Ungerleider, Sonia G. Rao, Amanda R. Wasylishen, Wesley D. Frey, James G. Jackson
Publikováno v:
Translational Oncology, Vol 11, Iss 4, Pp 930-940 (2018)
p53 is a transcription factor that regulates expression of genes involved in cell cycle arrest, senescence, and apoptosis. TP53 harbors mutations that inactivate its transcriptional activity in roughly 30% of breast cancers, and these tumors are much
Externí odkaz:
https://doaj.org/article/219224837bbe40a1ba8df7a8ee501849
Autor:
Guillermina Lozano, Jason B. Fleming, Amanda R. Wasylishen, Michelle C. Barton, Bin Liu, Anirban Maitra, Timothy P. Heffernan, Christopher A. Bristow, Florencia McAllister, Eugene J. Koay, Shunbin Xiong, Joy M. McDaniel, Ya'an Kang, Jithesh J. Augustine, Christian Siangco, Tara G. Hughes, Kendra L. Allton, Bingbing Dai, Yun Zhang, Jenying Deng, Xinqun Li, Michael P. Kim
Supplementary Figure 3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7660d885033ed528f78e469605aeae8c
https://doi.org/10.1158/2159-8290.22539451
https://doi.org/10.1158/2159-8290.22539451
Autor:
Guillermina Lozano, Jason B. Fleming, Amanda R. Wasylishen, Michelle C. Barton, Bin Liu, Anirban Maitra, Timothy P. Heffernan, Christopher A. Bristow, Florencia McAllister, Eugene J. Koay, Shunbin Xiong, Joy M. McDaniel, Ya'an Kang, Jithesh J. Augustine, Christian Siangco, Tara G. Hughes, Kendra L. Allton, Bingbing Dai, Yun Zhang, Jenying Deng, Xinqun Li, Michael P. Kim
Mutant p53-associated genes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69eec2c83bf1dfcb224158947f03f18e
https://doi.org/10.1158/2159-8290.22539442.v1
https://doi.org/10.1158/2159-8290.22539442.v1
Immunohistochemical staining of tumors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::047fbe080761b23c8f3246bb6c01af4c
https://doi.org/10.1158/1541-7786.22513396
https://doi.org/10.1158/1541-7786.22513396
Autor:
Guillermina Lozano, Swathi Arur, Paul J. Goodfellow, David G. Mutch, Adel K. El-Naggar, Laura Baseler, Bobbie J. Rimel, Amanda R. Wasylishen, Vinod Pant, Neeraj K. Aryal
Tumors and Metastasis in KRas+/LA1;Dicer+/2SD mice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cde849e5158b7c2ba3fc9ba794d8bc7
https://doi.org/10.1158/0008-5472.22418319.v1
https://doi.org/10.1158/0008-5472.22418319.v1
Autor:
Guillermina Lozano, Swathi Arur, Paul J. Goodfellow, David G. Mutch, Adel K. El-Naggar, Laura Baseler, Bobbie J. Rimel, Amanda R. Wasylishen, Vinod Pant, Neeraj K. Aryal
Dicer1 functions as a tumor suppressor in mouse models. In humans, somatic mutations are associated with many cancers in adults, and patients with DICER1 syndrome with DICER1 germline mutations are susceptible to childhood cancers. Dicer is phosphory
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::27a1f4ff00ef5131adf00d80e9f9005d
https://doi.org/10.1158/0008-5472.c.6510096.v1
https://doi.org/10.1158/0008-5472.c.6510096.v1