Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Amanda R. Taylor"'
Publikováno v:
Frontiers in Veterinary Science, Vol 10 (2023)
Novel therapies are needed for treatment of gliomas. Mebendazole previously demonstrated anti-neoplastic effects on canine glioma cell lines at in vitro mean inhibitory concentrations (IC50) of 10 ng/mL. Our study aimed to titrate the oral dose of me
Externí odkaz:
https://doaj.org/article/b132ae9caf3b454ba3044a1e10ac0164
Autor:
Irene B. Vazquez Fuster, Amanda R. Taylor, Annette N. Smith, Sue H. Duran, William R. Ravis, Shanese L. Jasper, Robert D. Arnold
Publikováno v:
Journal of Veterinary Internal Medicine, Vol 34, Iss 4, Pp 1563-1569 (2020)
Abstract Background Prolonged cytotoxic concentrations of cytarabine (CA) are required for maximum cytotoxicity. DepoCyt is a human liposomal cytarabine (LC) product that lasts longer in plasma and CSF compared with free CA (FC). The use of LC has no
Externí odkaz:
https://doaj.org/article/7c3801370dfc4426bede529a55a4420f
Autor:
Heather L. Gray-Edwards, Anne S. Maguire, Nouha Salibi, Lauren E. Ellis, Taylor L. Voss, Elise B. Diffie, Jey Koehler, Ashley N. Randle, Amanda R. Taylor, Brandon L. Brunson, Thomas S. Denney, Ronald J. Beyers, Atoska S. Gentry, Amanda L. Gross, Ana R. Batista, Miguel Sena-Esteves, Douglas R. Martin
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 17, Iss , Pp 258-270 (2020)
GM1 gangliosidosis (GM1) is a fatal neurodegenerative lysosomal storage disease that occurs most commonly in young children, with no effective treatment available. Long-term follow-up of GM1 cats treated by bilateral thalamic and deep cerebellar nucl
Externí odkaz:
https://doaj.org/article/e5a002b5c4934f989fe4e2733f002031
Autor:
Heather L. Gray-Edwards, Xuntian Jiang, Ashley N. Randle, Amanda R. Taylor, Taylor L. Voss, Aime K. Johnson, Victoria J. McCurdy, Miguel Sena-Esteves, Daniel S. Ory, Douglas R. Martin
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 6, Iss C, Pp 135-142 (2017)
GM1 gangliosidosis is a fatal lysosomal disorder, for which there is no effective treatment. Adeno-associated virus (AAV) gene therapy in GM1 cats has resulted in a greater than 6-fold increase in lifespan, with many cats remaining alive at >5.7 year
Externí odkaz:
https://doaj.org/article/3e3a1ecbcf1a457a8a1a35bcff0c25d7
Autor:
Sharon C. Kerwin, Amanda R. Taylor
Publikováno v:
Veterinary Clinics of North America: Small Animal Practice. 51:253-261
Diagnosis of forelimb lameness may be challenging, as it not only can be due to multiple common orthopedic diseases but also may occasionally be caused by neurologic disease. A thorough orthopedic and neurologic examination is key to determining whic
Autor:
Ronald J. Beyers, Ana Rita Batista, Heather L. Gray-Edwards, Miguel Sena-Esteves, Thomas S. Denney, Ashley N. Randle, Lauren E. Ellis, Jey W. Koehler, Nouha Salibi, Anne S Maguire, Taylor L. Voss, Amanda L. Gross, Elise B. Diffie, Amanda R. Taylor, Atoska S. Gentry, Douglas R. Martin, Brandon L. Brunson
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 17, Iss, Pp 258-270 (2020)
Molecular Therapy. Methods & Clinical Development
Molecular Therapy. Methods & Clinical Development
GM1 gangliosidosis (GM1) is a fatal neurodegenerative lysosomal storage disease that occurs most commonly in young children, with no effective treatment available. Long-term follow-up of GM1 cats treated by bilateral thalamic and deep cerebellar nucl
Autor:
William R. Ravis, Shanese L. Jasper, S. H. Duran, Annette N. Smith, Robert D. Arnold, Irene B. Vazquez Fuster, Amanda R. Taylor
Publikováno v:
Journal of Veterinary Internal Medicine
Journal of Veterinary Internal Medicine, Vol 34, Iss 4, Pp 1563-1569 (2020)
Journal of Veterinary Internal Medicine, Vol 34, Iss 4, Pp 1563-1569 (2020)
Background Prolonged cytotoxic concentrations of cytarabine (CA) are required for maximum cytotoxicity. DepoCyt is a human liposomal cytarabine (LC) product that lasts longer in plasma and CSF compared with free CA (FC). The use of LC has not been ev
Publikováno v:
Journal of Veterinary Emergency and Critical Care. 29:301-308
Objective To demonstrate the utility of advanced imaging in dogs with traumatic atlantoaxial subluxation (TAAS), and to report the presentation, treatment, and outcome for these dogs. Design Retrospective study (2009-2016). Setting University teachin
Autor:
Amanda R. Taylor, Sharon C. Kerwin
Publikováno v:
The Veterinary clinics of North America. Small animal practice. 51(2)
Although lameness of the thoracic limb typically is due to orthopedic disease, there are several important neurologic conditions that result in lameness. Neurologic diseases cause lameness due to disease of the nerves, nerve roots, spinal cord, or mu
Autor:
Jey W. Koehler, Ashley N. Randle, Jillian Gallagher, Amanda L. Gross, Elise B. Diffie, Brett D. Story, Sundeep Chandra, Sara Carl, Kayly Nielsen, Paul Cuddon, Miguel Sena-Esteves, Edwin H. Kolodny, Deborah Fernau, Amanda R. Taylor, Douglas R. Martin, Carly Corado, Xuntian Jiang, Heather L. Gray-Edwards, Annie S. Maguire, Toloo Taghian, Siauna Johnson
Publikováno v:
Mol Genet Metab
Tay-Sachs disease (TSD) is a fatal neurodegenerative disease caused by a deficiency of the enzyme β-N-acetylhexosaminidase A (HexA). TSD naturally occurs in Jacob sheep is the only experimental model of TSD. TSD in sheep recapitulates neurologic fea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69a0c7cda10ecdd0ead870203e1fd7ba
https://europepmc.org/articles/PMC8811770/
https://europepmc.org/articles/PMC8811770/