Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Amanda R. Magli"'
Autor:
Xiao-Jie Yan, Chao Gao, Yun Liu, Rosa Catera, Nicholas Chiorazzi, Kanti R. Rai, Steven L. Allen, Kostas Stamatopoulos, Charles C. Chu, Ten Feizi, Amanda R. Magli, Jonathan E. Kolitz
Publikováno v:
Molecular Medicine, Vol 23, Iss 1, Pp 1-12 (2017)
Amino acid replacement mutations in certain chronic lymphocytic leukemia (CLL) stereotyped B cell receptor (BCR) immunoglobulins (IGs) at defined positions within antigen-binding sites strongly imply antigen selection. Prime examples of this are CLL
Autor:
Jonathan E. Kolitz, Matthew D. Scharff, Patricia K. A. Mongini, Thomas MacCarthy, Lu Zhang, Kanti R. Rai, Rajendra N. Damle, Sergio Roa, Amanda R. Magli, Steven L. Allen, Piers E.M. Patten, Charles C. Chu, Emilia Albesiano, Xiao-Jie Yan, Dorothy Kim, Jacqueline C. Barrientos, Nicholas Chiorazzi
Publikováno v:
Blood. 120:4802-4811
Clonal evolution occurs during the course of chronic lymphocytic leukemia (CLL) and activation-induced deaminase (AID) could influence this process. However, this possibility has been questioned in CLL because the number of circulating AID mRNA+ cell
Autor:
Lu Zhang, Sebastien Didier, Saul Teichberg, Arjun Dhayalan, William J. Kennedy, Jonathan E. Kolitz, Rajendra N. Damle, Charles C. Chu, Amanda R. Magli, Briana M. Agagnina, Prasad Koduru, Gia Fraher, Xiao-Jie Yan, Steven L. Allen, Piers E.M. Patten, Kanti R. Rai, Nicholas Chiorazzi, Linda P. Johnson
Publikováno v:
Molecular Medicine. 17:1338-1348
An infectious etiology has been proposed for many human cancers, but rarely have specific agents been identified. One difficulty has been the need to propagate cancer cells in vitro to produce the infectious agent in detectable quantity. We hypothesi
Autor:
Nicholas Chiorazzi, Amanda R. Magli, Shabirul Haque, Steven L. Allen, Jonathan E. Kolitz, Charles C. Chu, Rajendra N. Damle, Kanti R. Rai, Emilia Albesiano, Lu Zhang, Xiao-Jie Yan, Patricia K. A. Mongini, Piers E.M. Patten, Dorothy Kim, Linda P. Johnson
Publikováno v:
Clinical Lymphoma Myeloma and Leukemia. 11:S226-S227
Autor:
Amanda R Magli, Veronica A. Rosales, Allyson J. Ocean, Joseph T. Ruggiero, Douglas Eric Guggenheim, Manish A. Shah, Paul J. Christos, Erika Ocampo Florendo, Irene Karpenko, Elizabeta C. Popa
Publikováno v:
Journal of Clinical Oncology. 31:e20549-e20549
e20549 Background: The impact and significance of malnutrition in gastrointestinal oncology is understudied. The Subjective Global Assessment (SGA) is a validated clinical tool to assess nutritional status. We examined baseline SGA to determine its s
Autor:
Lu Zhang, Jonathan E. Kolitz, Xiao-Jie Yan, Amanda R. Magli, Xiaoxuan Cui, Steven L. Allen, Charles C. Chu, Kanti R. Rai, Nicholas Chiorazzi, Jacqueline C. Barrientos
Publikováno v:
Blood. 120:1767-1767
Abstract 1767 B-cell chronic lymphocytic leukemia (CLL) is a clonal CD5+CD19+ B-lymphocyte cancer with a B cell receptor (BCR) immunoglobulin heavy chain variable (IGHV) gene sequence that may be classified as unmutated (U-CLL) or mutated (M-CLL) dep
Autor:
Kanti R. Rai, Steven L. Allen, Lu Zhang, Rosa Catera, Xiao-Jie Yan, Charles C. Chu, Amanda R. Magli, Jonathan E. Kolitz, Xiaoxuan Cui, Nicholas Chiorazzi
Publikováno v:
Blood. 118:624-624
Abstract 624 Clinical outcome in B-cell chronic lymphocytic leukemia (CLL) correlates with the amount of mutation in the leukemic clone's unique B-cell antigen receptor (BCR) sequence. Patients whose CLL clone has a mutated (>2% from germline) IGHV s
Autor:
William J Kennedy, Patricia K. A. Mongini, Nicholas Chiorazzi, Linda P Johnson, Amanda R. Magli, Shabirul Haque, Charles C. Chu, Lu Zhang, Steven L. Allen, Rajendra N. Damle, Emilia Albesiano, Kanti R. Rai, Xiao-Jie Yan, Jonathan E. Kolitz, Piers Em Patten
Publikováno v:
Blood. 116:2415-2415
Abstract 2415 Activation-induced cytidine deaminase (AID) is normally expressed in germinal center B cells and causes immunoglobulin somatic hypermutation and isotype class switching. High AID expression in B-cell chronic lymphocytic leukemia (CLL) a
Autor:
Rosa Catera, Kostas Stamatopoulos, Kanti R. Rai, Nicholas Chiorazzi, Amanda R. Magli, Steven L. Allen, Charles C. Chu, Jonathan E. Kolitz
Publikováno v:
Blood. 116:2444-2444
Abstract 2444 Extensive analysis of immunoglobulin gene sequences from chronic lymphocytic leukemia (CLL) patients reveals that ~30% carry stereotyped B-cell antigen receptors (BCRs) with highly homologous HCDR3s, over-represented in selected IGHV/IG
Autor:
Rosa Catera, Kanti R. Rai, Jonathan E. Kolitz, Amanda R. Magli, Nicholas Chiorazzi, Lu Zhang, Charles C. Chu, Xiaoxuan Cui, Steven L. Allen
Publikováno v:
Blood. 116:3900-3900
Abstract 3900 Many monoclonal antibodies (mAbs) produced by B-cell chronic lymphocytic leukemia (CLL) cells bind a subset of apoptotic cells that expose intracellular myosin on the cell surface. CLL patients with mAbs that bind these myosin-exposed a