Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Amanda R Robinson"'
Publikováno v:
PLoS Pathogens, Vol 8, Iss 2, p e1002516 (2012)
The Epstein-Barr virus (EBV) latent-lytic switch is mediated by the BZLF1 immediate-early protein. EBV is normally latent in memory B cells, but cellular factors which promote viral latency specifically in B cells have not been identified. In this re
Externí odkaz:
https://doaj.org/article/92ddfa3a88204ec9a40ece68d2426f37
Autor:
Sarah J Dickerson, Yongna Xing, Amanda R Robinson, William T Seaman, Henri Gruffat, Shannon C Kenney
Publikováno v:
PLoS Pathogens, Vol 5, Iss 3, p e1000356 (2009)
The switch between latent and lytic Epstein-Barr virus (EBV) infection is mediated by the viral immediate-early (IE) protein, BZLF1 (Z). Z, a homologue of c-jun that binds to AP1-like motifs (ZREs), induces expression of the BRLF1 (R) and BRRF1 (Na)
Externí odkaz:
https://doaj.org/article/8f261fa6325e48f2a2f688a2e99484ae
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Vol 8, Iss 2, p e1002516 (2012)
PLoS Pathogens, Vol 8, Iss 2, p e1002516 (2012)
The Epstein-Barr virus (EBV) latent-lytic switch is mediated by the BZLF1 immediate-early protein. EBV is normally latent in memory B cells, but cellular factors which promote viral latency specifically in B cells have not been identified. In this re
Autor:
Eveline K Hoebe, Erik S. Hopmans, Coral K. Wille, Jaap M. Middeldorp, Shannon C. Kenney, Astrid E. Greijer, Amanda R. Robinson
Publikováno v:
Journal of Virology, 86(20), 11322-11332. American Society for Microbiology
Journal of virology, 86(20), 11322-11332. American Society for Microbiology
Hoebe, E K, Wille, C, Hopmans, E S, Robinson, A R, Middeldorp, J M, Kenney, S C & Greijer, A E 2012, ' Epstein-Barr Virus Transcription Activator R Upregulates BARF1 Expression by Direct Binding to Its Promoter, Independent of Methylation ', Journal of Virology, vol. 86, no. 20, pp. 11322-11332 . https://doi.org/10.1128/JVI.01161-12
Journal of virology, 86(20), 11322-11332. American Society for Microbiology
Hoebe, E K, Wille, C, Hopmans, E S, Robinson, A R, Middeldorp, J M, Kenney, S C & Greijer, A E 2012, ' Epstein-Barr Virus Transcription Activator R Upregulates BARF1 Expression by Direct Binding to Its Promoter, Independent of Methylation ', Journal of Virology, vol. 86, no. 20, pp. 11322-11332 . https://doi.org/10.1128/JVI.01161-12
Epstein-Barr virus (EBV) BamHI-A rightward frame 1 (BARF1) is considered a major viral oncogene in epithelial cells and has immune-modulating properties. However, in B cells and lymphomas, BARF1 expression is restricted to the viral lytic replication
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50cf228956775788c2a12f59532a5c31
https://research.vumc.nl/en/publications/47bde26e-b176-4686-b8fc-03e5140c1e16
https://research.vumc.nl/en/publications/47bde26e-b176-4686-b8fc-03e5140c1e16
Publikováno v:
Journal of virology. 85(17)
The Epstein-Barr virus (EBV) latent-to-lytic switch is an essential part of the viral life cycle, but the cellular factors that promote viral reactivation are not well defined. In this report, we demonstrate that the cellular transcription factor Oct
Publikováno v:
Journal of virology. 84(23)
The Epstein-Barr virus immediate-early protein, BZLF1 (Z), initiates the switch between latent and lytic infection and plays an essential role in mediating viral replication. Z also inhibits expression of the major receptor for tumor necrosis factor